Molecular mechanisms mediating asymmetric subcellular localisation of the core planar polarity pathway proteins

Activity of Smurf2 Ubiquitin Ligase Is Regulated by the Wnt Pathway Protein Dishevelled

(2020) Ondrej Bernatik et al.   Cells

Vangl2 interaction plays a role in the proteasomal degradation of Prickle2

(2019) Tadahiro Nagaoka et al.   Scientific Reports

PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling

(2019) Adnan Shami Shah et al.   Cell Reports

Reciprocal action of Casein Kinase Iε on core planar polarity proteins regulates clustering and asymmetric localisation

(2019) Helen Strutt et al.   eLife

Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear

(2019) Cristy Tower-Gilchrist et al.   MOLECULAR BIOLOGY OF THE CELL

The Control Centers of Biomolecular Phase Separation: How Membrane Surfaces, PTMs, and Active Processes Regulate Condensation

(2019) Wilton T. Snead et al.   MOLECULAR CELL

Update on the Role of the Non-Canonical Wnt/Planar Cell Polarity Pathway in Neural Tube Defects

(2019) Wang et al.   Cells

Establishing and transducing cell polarity: common themes and variations

(2018) Daniel St Johnston   CURRENT OPINION IN CELL BIOLOGY

Prickle is phosphorylated by Nemo and targeted for degradation to maintain Prickle/Spiny-legs isoform balance during planar cell polarity establishment

(2018) Giovanna M. Collu et al.   PLoS Genetics

Rapid Disruption of Dishevelled Activity Uncovers an Intercellular Role in Maintenance of Prickle in Core Planar Polarity Protein Complexes

(2018) Margarida Ressurreição et al.   Cell Reports

Planar cell polarity in development and disease

(2017) Mitchell T. Butler et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Planar cell polarity (PCP) proteins and spermatogenesis

(2016) Haiqi Chen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Robust Asymmetric Localization of Planar Polarity Proteins Is Associated with Organization into Signalosome-like Domains of Variable Stoichiometry

(2016) Helen Strutt et al.   Cell Reports

Frizzled-Induced Van Gogh Phosphorylation by CK1ε Promotes Asymmetric Localization of Core PCP Factors in Drosophila

(2016) Lindsay K. Kelly et al.   Cell Reports

Conservation of Planar Polarity Pathway Function Across the Animal Kingdom

(2015) Rosalind Hale et al.   Annual Review of Genetics

Mitotic Control of Planar Cell Polarity by Polo-like Kinase 1

(2015) Rezma Shrestha et al.   DEVELOPMENTAL CELL

Clustering and Negative Feedback by Endocytosis in Planar Cell Polarity Signaling Is Modulated by Ubiquitinylation of Prickle

(2015) Bomsoo Cho et al.   PLoS Genetics

Cellular interpretation of the long-range gradient of Four-jointed activity in the Drosophila wing

(2015) Rosalind Hale et al.   eLife

Planar polarization of Vangl2 in the vertebrate neural plate is controlled by Wnt and Myosin II signaling

(2015) O. Ossipova et al.   Biology Open

The cell biology of planar cell polarity

(2014) Danelle Devenport   JOURNAL OF CELL BIOLOGY

Microtubules provide directional information for core PCP function

(2014) Maja Matis et al.   eLife

A Cul-3-BTB ubiquitylation pathway regulates junctional levels and asymmetry of core planar polarity proteins

(2013) H. Strutt et al.   DEVELOPMENT

Systematic Screening of a Drosophila ORF Library In Vivo Uncovers Wnt/Wg Pathway Components

(2013) Claus Schertel et al.   DEVELOPMENTAL CELL

Wg and Wnt4 provide long-range directional input to planar cell polarity orientation in Drosophila

(2013) Jun Wu et al.   NATURE CELL BIOLOGY

Strabismus Promotes Recruitment and Degradation of Farnesylated Prickle in Drosophila melanogaster Planar Polarity Specification

(2013) Helen Strutt et al.   PLoS Genetics

Planar Polarity Specification through Asymmetric Subcellular Localization of Fat and Dachsous

(2012) Amy Brittle et al.   CURRENT BIOLOGY

Propagation of Dachsous-Fat Planar Cell Polarity

(2012) Abhijit A. Ambegaonkar et al.   CURRENT BIOLOGY

Establishment of Global Patterns of Planar Polarity during Growth of the Drosophila Wing Epithelium

(2012) Andreas Sagner et al.   CURRENT BIOLOGY

Dissecting the molecular bridges that mediate the function of Frizzled in planar cell polarity

(2012) G. Struhl et al.   DEVELOPMENT

Molecular Characterisation of Endogenous Vangl2/Vangl1 Heteromeric Protein Complexes

(2012) Edwige Belotti et al.   PLoS One

Wnt/ -catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled

(2012) D. V. F. Tauriello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical Control of Morphogenesis by Fat/Dachsous/Four-Jointed Planar Cell Polarity Pathway

(2012) F. Bosveld et al.   SCIENCE

Multi-Cellular Rosettes in the Mouse Visceral Endoderm Facilitate the Ordered Migration of Anterior Visceral Endoderm Cells

(2012) Georgios Trichas et al.   PLOS BIOLOGY

Getting to the heart of planar cell polarity signaling

(2011) Deborah J. Henderson et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Principles of planar polarity in animal development

(2011) L. V. Goodrich et al.   DEVELOPMENT

Functional dissection of phosphorylation of Disheveled in Drosophila

(2011) Wang A. Yanfeng et al.   DEVELOPMENTAL BIOLOGY

Dynamics of Core Planar Polarity Protein Turnover and Stable Assembly into Discrete Membrane Subdomains

(2011) Helen Strutt et al.   DEVELOPMENTAL CELL

Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2

(2011) Bo Gao et al.   DEVELOPMENTAL CELL

Mink1 Regulates  -Catenin-Independent Wnt Signaling via Prickle Phosphorylation

(2011) A. M. Daulat et al.   MOLECULAR AND CELLULAR BIOLOGY

Mitotic internalization of planar cell polarity proteins preserves tissue polarity

(2011) Danelle Devenport et al.   NATURE CELL BIOLOGY

Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin–β-catenin

(2011) Ivana Mirkovic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium of Drosophila

(2010) Benoît Aigouy et al.   CELL

Ubiquitin: Same Molecule, Different Degradation Pathways

(2010) Michael J. Clague et al.   CELL

Four-Jointed Modulates Growth and Planar Polarity by Reducing the Affinity of Dachsous for Fat

(2010) Amy L. Brittle et al.   CURRENT BIOLOGY

Modulation of Fat:Dachsous Binding by the Cadherin Domain Kinase Four-Jointed

(2010) Michael A. Simon et al.   CURRENT BIOLOGY

Abelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylation

(2010) J. Singh et al.   GENES & DEVELOPMENT

Modelling and Analysis of Planar Cell Polarity

(2009) S. Schamberg et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases

(2009) Masahiro Narimatsu et al.   CELL

Order and Stochastic Dynamics in Drosophila Planar Cell Polarity

(2009) Yoram Burak et al.   PLoS Computational Biology

Asymmetric Homotypic Interactions of the Atypical Cadherin Flamingo Mediate Intercellular Polarity Signaling

(2008) Wei-Shen Chen et al.   CELL

Differential Stability of Flamingo Protein Complexes Underlies the Establishment of Planar Polarity

(2008) Helen Strutt et al.   CURRENT BIOLOGY

Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles

(2008) Danelle Devenport et al.   NATURE CELL BIOLOGY