Proteomic Profiling Reveals Roles of Stress Response, Ca 2+ Transient Dysregulation, and Novel Signaling Pathways in Alcohol‐Induced Cardiotoxicity

Using Death Certificates to Explore Changes in Alcohol‐Related Mortality in the United States, 1999 to 2017

(2020) Aaron M. White et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Corin Overexpression Reduces Myocardial Infarct Size and Modulates Cardiomyocyte Apoptotic Cell Death

(2020) Ryan D. Sullivan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Unchain My Heart: Integrins at the Basis of iPSC Cardiomyocyte Differentiation

(2019) Rosaria Santoro et al.   Stem Cells International

Cardiac Toxicity from Ethanol Exposure in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

(2019) Antonio Rampoldi et al.   TOXICOLOGICAL SCIENCES

hiPSCs in cardio-oncology: deciphering the genomics

(2019) Emily A Pinheiro et al.   CARDIOVASCULAR RESEARCH

Attenuation of doxorubicin-induced cardiotoxicity in a human in vitro cardiac model by the induction of the NRF-2 pathway

(2019) Lauren Tomlinson et al.   BIOMEDICINE & PHARMACOTHERAPY

Alcohol use disorders and the heart

(2019) Ed Day et al.   ADDICTION

MLP-deficient human pluripotent stem cell derived cardiomyocytes develop hypertrophic cardiomyopathy and heart failure phenotypes due to abnormal calcium handling

(2019) Xiaowei Li et al.   Cell Death & Disease

Parental alcohol consumption and the risk of congenital heart diseases in offspring: An updated systematic review and meta-analysis

(2019) Senmao Zhang et al.   European Journal of Preventive Cardiology

Cardiomyocyte-Specific Deficiency of HSPB1 Worsens Cardiac Dysfunction by Activating NFκB-Mediated Leukocyte Recruitment After Myocardial Infarction

(2018) Yana Wang et al.   CARDIOVASCULAR RESEARCH

SR Ca 2+ -leak and disordered excitation-contraction coupling as the basis for arrhythmogenic and negative inotropic effects of acute ethanol exposure

(2018) Julian Mustroph et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Ethanol-induced cardiomyocyte toxicity implicit autophagy and NFkB transcription factor

(2018) Jessica Maiuolo et al.   PHARMACOLOGICAL RESEARCH

Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) Max G Griswold et al.   LANCET

Resveratrol protects cardiomyocytes against anoxia/reoxygenation via dephosphorylation of VDAC1 by Akt-GSK3 β pathway

(2018) Mengyuan Tian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mechanisms of cardiac ethanol toxicity and novel treatment options

(2018) Julian Mustroph et al.   PHARMACOLOGY & THERAPEUTICS

On the contribution of mass spectrometry-based platforms to the field of personalized oncology

(2018) Eleonora Orlando et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Alcohol Abuse and Cardiac Disease

(2017) Isaac R. Whitman et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions

(2017) Vinay Swaminathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CPNE1 Is a Useful Prognostic Marker and Is Associated with TNF Receptor-Associated Factor 2 (TRAF2) Expression in Prostate Cancer

(2017) Jiabei Liang et al.   MEDICAL SCIENCE MONITOR

Is There a Potential Therapeutic Role for Caveolin-1 in Fibrosis?

(2017) Waled A. Shihata et al.   Frontiers in Pharmacology

Worldwide Prevalence of Fetal Alcohol Spectrum Disorders: A Systematic Literature Review Including Meta-Analysis

(2016) Sylvia Roozen et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Animal Models of Congenital Cardiomyopathies Associated With Mutations in Z-Line Proteins

(2016) Marie-Louise Bang   JOURNAL OF CELLULAR PHYSIOLOGY

miR-21-3p controls sepsis-associated cardiac dysfunction via regulating SORBS2

(2016) Hui Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Alcohol and Atrial Fibrillation

(2016) Aleksandr Voskoboinik et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mass-spectrometric exploration of proteome structure and function

(2016) Ruedi Aebersold et al.   NATURE

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Origins of mass spectrometry-based proteomics

(2016) Matthias Mann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart

(2016) Sofia Hirth et al.   PLoS One

NOX2 amplifies acetaldehyde-mediated cardiomyocyte mitochondrial dysfunction in alcoholic cardiomyopathy

(2016) Moritz Brandt et al.   Scientific Reports

Regulation of Cardiac Remodeling by Cardiac Na+/K+-ATPase Isoforms

(2016) Lijun Liu et al.   Frontiers in Physiology

Integrin-Associated Focal Adhesion Kinase Protects Human Embryonic Stem Cells from Apoptosis, Detachment, and Differentiation

(2016) Loriana Vitillo et al.   Stem Cell Reports

Simulated Microgravity and 3D Culture Enhance Induction, Viability, Proliferation and Differentiation of Cardiac Progenitors from Human Pluripotent Stem Cells

(2016) Rajneesh Jha et al.   Scientific Reports

lncRNA H19/miR-675 axis regulates cardiomyocyte apoptosis by targeting VDAC1 in diabetic cardiomyopathy

(2016) Xiangquan Li et al.   Scientific Reports

Na+/Ca2+exchange and Na+/K+-ATPase in the heart

(2015) Michael J. Shattock et al.   JOURNAL OF PHYSIOLOGY-LONDON

Systematic Investigation of Cellular Response and Pleiotropic Effects in Atorvastatin-Treated Liver Cells by MS-Based Proteomics

(2015) Haopeng Xiao et al.   JOURNAL OF PROTEOME RESEARCH

Antioxidant responses and cellular adjustments to oxidative stress

(2015) Cristina Espinosa-Diez et al.   Redox Biology

Top-down Proteomics Reveals Concerted Reductions in Myofilament and Z-disc Protein Phosphorylation after Acute Myocardial Infarction

(2014) Ying Peng et al.   MOLECULAR & CELLULAR PROTEOMICS

Chemically defined generation of human cardiomyocytes

(2014) Paul W Burridge et al.   NATURE METHODS

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Integrin-linked kinase mediates force transduction in cardiomyocytes by modulating SERCA2a/PLN function

(2014) Alexandra Traister et al.   Nature Communications

Role of α-crystallin B as a regulatory switch in modulating cardiomyocyte apoptosis by mitochondria or endoplasmic reticulum during cardiac hypertrophy and myocardial infarction

(2013) A Mitra et al.   Cell Death & Disease

Facilitated ethanol metabolism promotes cardiomyocyte contractile dysfunction through autophagy in murine hearts

(2012) Rui Guo et al.   Autophagy

HSPBs: Small proteins with big implications in human disease

(2012) Harm H. Kampinga et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Angiotensin II Plays a Critical Role in Alcohol-Induced Cardiac Nitrative Damage, Cell Death, Remodeling, and Cardiomyopathy in a Protein Kinase C/Nicotinamide Adenine Dinucleotide Phosphate Oxidase–Dependent Manner

(2012) Yi Tan et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Slow Cardiac Myosin Regulatory Light Chain in Heart Failure

(2011) Daniel F. Pauly   CLINICAL CARDIOLOGY

Pathway analysis of dilated cardiomyopathy using global proteomic profiling and enrichment maps

(2010) Ruth Isserlin et al.   PROTEOMICS

Mutations in Alpha-Actinin-2 Cause Hypertrophic Cardiomyopathy

(2009) Christine Chiu et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Integrin-linked kinase - essential roles in physiology and cancer biology

(2008) P. C. McDonald et al.   JOURNAL OF CELL SCIENCE