A simple open source bioinformatic methodology for initial exploration of GPCR ligands’ agonistic/antagonistic properties
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A simple open source bioinformatic methodology for initial exploration of GPCR ligands’ agonistic/antagonistic properties
Authors
Keywords
-
Journal
Pharmacology Research & Perspectives
Volume 8, Issue 4, Pages -
Publisher
Wiley
Online
2020-07-14
DOI
10.1002/prp2.600
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- 2018 FDA drug approvals
- (2019) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
- (2019) Michael Lückmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacogenomics of GPCR Drug Targets
- (2018) Alexander S. Hauser et al. CELL
- 2017 FDA drug approvals
- (2018) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Subcellular Organization of GPCR Signaling
- (2018) Kelsie Eichel et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Chemical Diversity in the G Protein-Coupled Receptor Superfamily
- (2018) Márton Vass et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- New Insights into Modes of GPCR Activation
- (2018) Wenjing Wang et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727
- (2018) Nathan Robertson et al. NATURE
- Cryo-EM structure of human rhodopsin bound to an inhibitory G protein
- (2018) Yanyong Kang et al. NATURE
- Structure of the adenosine-bound human adenosine A1 receptor–Gi complex
- (2018) Christopher J. Draper-Joyce et al. NATURE
- Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go
- (2018) Javier García-Nafría et al. NATURE
- Structure of the µ-opioid receptor–Gi protein complex
- (2018) Antoine Koehl et al. NATURE
- Computational design of ligand-binding membrane receptors with high selectivity
- (2017) Xiang Feng et al. Nature Chemical Biology
- Trends in GPCR drug discovery: new agents, targets and indications
- (2017) Alexander S. Hauser et al. NATURE REVIEWS DRUG DISCOVERY
- Antagonizing effects of membrane-acting androgens on the eicosanoid receptor OXER1 in prostate cancer
- (2017) Konstantina Kalyvianaki et al. Scientific Reports
- Open source molecular modeling
- (2016) Somayeh Pirhadi et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- A comprehensive map of molecular drug targets
- (2016) Rita Santos et al. NATURE REVIEWS DRUG DISCOVERY
- Galaxy7TM: flexible GPCR–ligand docking by structure refinement
- (2016) Gyu Rie Lee et al. NUCLEIC ACIDS RESEARCH
- ZINC 15 – Ligand Discovery for Everyone
- (2015) Teague Sterling et al. Journal of Chemical Information and Modeling
- Improvements, trends, and new ideas in molecular docking: 2012-2013 in review
- (2015) Elizabeth Yuriev et al. JOURNAL OF MOLECULAR RECOGNITION
- Effective protein model structure refinement by loop modeling and overall relaxation
- (2015) Gyu Rie Lee et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Design and synthesis of 21-alkynylaryl pregnenolone derivatives and evaluation of their anticancer activity
- (2014) György Szalóki et al. BIOORGANIC & MEDICINAL CHEMISTRY
- SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information
- (2014) Marco Biasini et al. NUCLEIC ACIDS RESEARCH
- GalaxyDock2: Protein-ligand docking using beta-complex and global optimization
- (2013) Woong-Hee Shin et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- GalaxyRefine: protein structure refinement driven by side-chain repacking
- (2013) Lim Heo et al. NUCLEIC ACIDS RESEARCH
- The ChEMBL bioactivity database: an update
- (2013) A. Patrícia Bento et al. NUCLEIC ACIDS RESEARCH
- Action of Molecular Switches in GPCRs - Theoretical and Experimental Studies
- (2012) B. Trzaskowski et al. CURRENT MEDICINAL CHEMISTRY
- QSAR Modeling is not “Push a Button and Find a Correlation”: A Case Study of Toxicity of (Benzo-)triazoles on Algae
- (2012) Paola Gramatica et al. Molecular Informatics
- Novel Oligomeric Proanthocyanidin Derivatives Interact with Membrane Androgen Sites and Induce Regression of Hormone-Independent Prostate Cancer
- (2011) M. Kampa et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Crystal structure of the β2 adrenergic receptor–Gs protein complex
- (2011) Søren G. F. Rasmussen et al. NATURE
- Open Babel: An open chemical toolbox
- (2011) Noel M O'Boyle et al. Journal of Cheminformatics
- G protein-coupled receptors: novel targets for drug discovery in cancer
- (2010) Rosamaria Lappano et al. NATURE REVIEWS DRUG DISCOVERY
- HexServer: an FFT-based protein docking server powered by graphics processors
- (2010) G. Macindoe et al. NUCLEIC ACIDS RESEARCH
- Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist
- (2010) E. Y. T. Chien et al. SCIENCE
- Structural diversity of G protein-coupled receptors and significance for drug discovery
- (2008) Malin C. Lagerström et al. NATURE REVIEWS DRUG DISCOVERY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now