Biomarkers for Liquid Biopsies of Pituitary Neuroendocrine Tumors

Comprehensive analysis of potential prognostic genes for the construction of a competing endogenous RNA regulatory network in hepatocellular carcinoma

(2019) Chaosen Yue et al.   OncoTargets and Therapy

Epigenetic Biomarkers in Cell-Free DNA and Applications in Liquid Biopsy

(2019) Wanxia Gai et al.   Genes

Molecular Network Basis of Invasive Pituitary Adenoma: A Review

(2019) Qi Yang et al.   Frontiers in Endocrinology

Acromegaly

(2019) Annamaria Colao et al.   Nature Reviews Disease Primers

PTTG overexpression in non-functioning pituitary adenomas: Correlation with invasiveness, female gender and younger age

(2019) Geraldine Trott et al.   Annals of Diagnostic Pathology

Comprehensive analysis of circulating microRNAs in plasma of patients with pituitary adenomas

(2019) Kinga Németh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genome-wide cell-free DNA (cfDNA) methylation signatures and effect on tissue of origin (TOO) performance.

(2019) Minetta C. Liu et al.   JOURNAL OF CLINICAL ONCOLOGY

RPSAP52 lncRNA is overexpressed in pituitary tumors and promotes cell proliferation by acting as miRNA sponge for HMGA proteins

(2019) Daniela D’Angelo et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Analysis of Tumor Angiogenesis and Immune Microenvironment in Non-Functional Pituitary Endocrine Tumors

(2019) Mizuto Sato et al.   Journal of Clinical Medicine

Long noncoding RNA PVT1 : A highly dysregulated gene in malignancy

(2019) Soudeh Ghafouri‐Fard et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Identification of Serum miRNA-423-5p Expression Signature in Somatotroph Adenomas

(2019) Sida Zhao et al.   International Journal of Endocrinology

FOXP1-induced lncRNA CLRN1-AS1 acts as a tumor suppressor in pituitary prolactinoma by repressing the autophagy via inactivating Wnt/β-catenin signaling pathway

(2019) Chao Wang et al.   Cell Death & Disease

PVT1 Promotes Cancer Progression via MicroRNAs

(2019) Wenxi Wang et al.   Frontiers in Oncology

MiR-1299 promotes the synthesis and secretion of prolactin by inhibiting FOXO1 expression in drug-resistant prolactinomas

(2019) Zheng Xiao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Exosome-transmitted lncRNA H19 inhibits the growth of pituitary adenoma

(2019) Yong Zhang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Exosomal hsa-miR-21-5p derived from growth hormone-secreting pituitary adenoma promotes abnormal bone formation in acromegaly

(2019) Yuanyuan Xiong et al.   Translational Research

LncRNA XIST depletion prevents cancer progression in invasive pituitary neuroendocrine tumor by inhibiting bFGF via upregulation of microRNA-424-5p

(2019) Kai Zhou et al.   OncoTargets and Therapy

The prognostic value of long noncoding RNA SNHG16 on clinical outcomes in human cancers: a systematic review and meta-analysis

(2019) Chenghao Zhang et al.   Cancer Cell International

Long Non-Coding RNA Plasmacytoma Variant Translocation 1 (PVT1) Enhances Proliferation, Migration, and Epithelial-Mesenchymal Transition (EMT) of Pituitary Adenoma Cells by Activating β-Catenin, c-Myc, and Cyclin D1 Expression

(2019) Yihua Zhang et al.   MEDICAL SCIENCE MONITOR

Detection of circulating tumor cells in patients with pituitary tumors

(2018) Gao Hua et al.   BMC CANCER

Long non coding RNA XIST as a prognostic cancer marker – A meta-analysis

(2018) Qun Zhou et al.   CLINICA CHIMICA ACTA

Association of urinary and plasma DNA in early breast cancer patients and its links to disease relapse

(2018) Z. Liu et al.   Clinical & Translational Oncology

The Epigenomic Landscape of Pituitary Adenomas Reveals Specific Alterations and Differentiates Among Acromegaly, Cushing's Disease and Endocrine-Inactive Subtypes

(2018) Matthew P. Salomon et al.   CLINICAL CANCER RESEARCH

Genomic Alterations in Sporadic Pituitary Tumors

(2018) Wenya Linda Bi et al.   Current Neurology and Neuroscience Reports

MicroRNAs and Target Genes in Pituitary Adenomas

(2018) Yajuan Feng et al.   HORMONE AND METABOLIC RESEARCH

Expression of the long non-coding RNA H19 and MALAT-1 in growth hormone-secreting pituitary adenomas and its relationship to tumor behavior

(2018) Tianyu Lu et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Genomic Alterations and Complex Subclonal Architecture in Sporadic GH-Secreting Pituitary Adenomas

(2018) Mirella Hage et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Epigenetics of pituitary tumors: Pathogenetic and therapeutic implications

(2018) Shereen Ezzat et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

‘Liquid biopsy’ for cancer promises early detection

(2018) Jocelyn Kaiser   SCIENCE

Overexpression of DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) And DNA (Cytosine-5)-Methyltransferase 3A (DNMT3A) Is Associated with Aggressive Behavior and Hypermethylation of Tumor Suppressor Genes in Human Pituitary Adenomas

(2018) Hou-Shi Ma et al.   MEDICAL SCIENCE MONITOR

Lnc-SNHG1 Activates the TGFBR2/SMAD3 and RAB11A/Wnt/β-Catenin Pathway by Sponging MiR-302/372/373/520 in Invasive Pituitary Tumors

(2018) Heyuan Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Long-noncoding RNA IFNG-AS1 exerts oncogenic properties by interacting with epithelial splicing regulatory protein 2 (ESRP2) in pituitary adenomas

(2018) Guohui Lu et al.   PATHOLOGY RESEARCH AND PRACTICE

Identification of recurrent USP48 and BRAF mutations in Cushing’s disease

(2018) Jianhua Chen et al.   Nature Communications

Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours

(2018) Ze Rui Wu et al.   Nature Communications

Genome-wide identification of lncRNAs and mRNAs differentially expressed in non-functioning pituitary adenoma and construction of an lncRNA-mRNA co-expression network

(2018) Weikang Xing et al.   Biology Open

Clinical Identification of Oncogenic Drivers and Copy-Number Alterations in Pituitary Tumors

(2017) Wenya Linda Bi et al.   ENDOCRINOLOGY

Relationship between RSUME and HIF-1α/VEGF-A with invasion of pituitary adenoma

(2017) Wei He et al.   GENE

Long non-coding RNA C5orf66-AS1 is downregulated in pituitary null cell adenomas and is associated with their invasiveness

(2017) Guoqiang Yu et al.   ONCOLOGY REPORTS

Increased expression of the microRNA 106b~25 cluster and its host gene MCM7 in corticotroph pituitary adenomas is associated with tumor invasion and Crooke’s cell morphology

(2017) Filip Garbicz et al.   Pituitary

New evidence that a large proportion of human blood plasma cell-free DNA is localized in exosomes

(2017) M. Rohan Fernando et al.   PLoS One

Study on mirnas’ expression for the invasion of pituitary adenomas

(2017) Yu Guoqiang et al.   Turkish Neurosurgery

Circular RNA hsa_circ_0000745 may serve as a diagnostic marker for gastric cancer

(2017) Mei Huang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Effect of miR-106b on Invasiveness of Pituitary Adenoma via PTEN-PI3K/AKT

(2017) Zhiming Zheng et al.   MEDICAL SCIENCE MONITOR

Cell-free microRNAs in blood and other body fluids, as cancer biomarkers

(2016) Blanca Ortiz-Quintero   CELL PROLIFERATION

The genome-wide mutational landscape of pituitary adenomas

(2016) Zhi-Jian Song et al.   CELL RESEARCH

Landscape of Genomic Alterations in Pituitary Adenomas

(2016) Wenya Linda Bi et al.   CLINICAL CANCER RESEARCH

The role of microRNAs in the pathogenesis of pituitary tumors

(2016) Qiu juan Zhang   Frontiers in Bioscience-Landmark

Evaluation and comparison of in vitro degradation kinetics of DNA in serum, urine and saliva: A qualitative study

(2016) Wang Yao et al.   GENE

Differential DNA methylome profiling of nonfunctioning pituitary adenomas suggesting tumour invasion is correlated with cell adhesion

(2016) Ye Gu et al.   JOURNAL OF NEURO-ONCOLOGY

Plasma extracellular RNA profiles in healthy and cancer patients

(2016) Tiezheng Yuan et al.   Scientific Reports

MiR-132, miR-15a and miR-16 synergistically inhibit pituitary tumor cell proliferation, invasion and migration by targeting Sox5

(2015) Wang Renjie et al.   CANCER LETTERS

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

(2015) Yan Li et al.   CELL RESEARCH

Recurrent gain-of-function USP8 mutations in Cushing's disease

(2015) Zeng-Yi Ma et al.   CELL RESEARCH

Chromothripsis in cancer cells: An update

(2015) Agata Rode et al.   INTERNATIONAL JOURNAL OF CANCER

Gene expression in prolactinomas: a systematic review

(2015) Justin Seltzer et al.   Pituitary

The PTTG1-targeting miRNAs miR-329, miR-300, miR-381, and miR-655 inhibit pituitary tumor cell tumorigenesis and are involved in a p53/PTTG1 regulation feedback loop

(2015) Hai-qian Liang et al.   Oncotarget

Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes

(2014) Ugur Gezer et al.   CELL BIOLOGY INTERNATIONAL

Management of aggressive pituitary adenomas and pituitary carcinomas

(2014) Anthony Heaney   JOURNAL OF NEURO-ONCOLOGY

Mutations in the deubiquitinase gene USP8 cause Cushing's disease

(2014) Martin Reincke et al.   NATURE GENETICS

MicroRNAs as Biomarkers in Pituitary Tumors

(2014) Antonio Di Ieva et al.   NEUROSURGERY

Analysis of the RNA content of the exosomes derived from blood serum and urine and its potential as biomarkers

(2014) M. Li et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Expression of the long non-coding RNAs MEG3, HOTAIR, and MALAT-1 in non-functioning pituitary adenomas and their relationship to tumor behavior

(2014) Zhenye Li et al.   Pituitary

A Pilot Genome-Scale Profiling of DNA Methylation in Sporadic Pituitary Macroadenomas: Association with Tumor Invasion and Histopathological Subtype

(2014) Chao Ling et al.   PLoS One

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Plasma long noncoding RNA protected by exosomes as a potential stable biomarker for gastric cancer

(2014) Qier Li et al.   TUMOR BIOLOGY

Pituitary Adenoma Biomarkers Identified Using Proteomic Fingerprint Technology

(2013) Kai-Yu Zhou et al.   Asian Pacific Journal of Cancer Prevention

DNA Methylation in the Malignant Transformation of Meningiomas

(2013) Fan Gao et al.   PLoS One

Silencing of RASSF3 by DNA Hypermethylation Is Associated with Tumorigenesis in Somatotroph Adenomas

(2013) Hu Peng et al.   PLoS One

miRNA Gene Promoters Are Frequent Targets of Aberrant DNA Methylation in Human Breast Cancer

(2013) Lukas Vrba et al.   PLoS One

The Role of Epigenetic Modification in Tumorigenesis and Progression of Pituitary Adenomas: A Systematic Review of the Literature

(2013) Matthew Pease et al.   PLoS One

Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing

(2012) K. C. A. Chan et al.   CLINICAL CHEMISTRY

GADD45 Proteins: Central Players in Tumorigenesis

(2012) R. E. Tamura et al.   CURRENT MOLECULAR MEDICINE

Quantitative, genome-wide analysis of the DNA methylome in sporadic pituitary adenomas

(2012) Cuong V Duong et al.   ENDOCRINE-RELATED CANCER

Salivary lncRNA as a potential marker for oral squamous cell carcinoma diagnosis

(2012) HAIKUO TANG et al.   Molecular Medicine Reports

Over-expression of vascular endothelial growth factor in pituitary adenomas is associated with extrasellar growth and recurrence

(2012) Ruth Sánchez-Ortiga et al.   Pituitary

The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes

(2012) Alessia Gallo et al.   PLoS One

Determination of the differential expression of mitochondrial long non-coding RNAs as a noninvasive diagnosis of bladder cancer

(2012) Alexis Rivas et al.   BMC Urology

Proteomic Analysis of Two Types of Exosomes in Human Whole Saliva

(2011) Yuko Ogawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

MicroRNAs in the Human Pituitary

(2011) Milani Sivapragasam et al.   ENDOCRINE PATHOLOGY

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

Characterization of extracellular circulating microRNA

(2011) Andrey Turchinovich et al.   NUCLEIC ACIDS RESEARCH

Expression of cell growth negative regulators MEG3 and GADD45γ is lost in most sporadic human pituitary adenomas

(2011) Lisiane Cervieri Mezzomo et al.   Pituitary

High Fragmentation Characterizes Tumour-Derived Circulating DNA

(2011) Florent Mouliere et al.   PLoS One

Differential expression of microRNAs in GH-secreting pituitary adenomas

(2010) Zhi-Gang Mao et al.   Diagnostic Pathology

MicroRNAs and Their Therapeutic Potential for Human Diseases: MicroRNAs, miR-143 and -145, Function as Anti-oncomirs and the Application of Chemically Modified miR-143 as an Anti-cancer Drug

(2010) Yukio Kitade et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

HMGA2: A pituitary tumour subtype-specific oncogene?

(2010) Monica Fedele et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Small nucleolar RNA signatures as biomarkers for non-small-cell lung cancer

(2010) Jipei Liao et al.   Molecular Cancer

Detection of Mutated K-rasDNA in Urine, Plasma, and Serum of Patients with Colorectal Carcinoma or Adenomatous Polyps

(2009) Ying-Hsiu Su et al.   Annals of the New York Academy of Sciences

Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer

(2009) J Nilsson et al.   BRITISH JOURNAL OF CANCER

Aberrant DNA methylation in contrast with mutations

(2009) Toshikazu Ushijima et al.   CANCER SCIENCE

Epigenetic Control in Pituitary Tumors

(2009) Shereen EZZAT   ENDOCRINE JOURNAL

Loss of neuronatin expression is associated with promoter hypermethylation in pituitary adenoma

(2009) K Revill et al.   ENDOCRINE-RELATED CANCER

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

(2009) Mariantonia Logozzi et al.   PLoS One

Significance of Circulating Tumor Cells Detected by the CellSearch System in Patients with Metastatic Breast Colorectal and Prostate Cancer

(2009) M. Craig Miller et al.   Journal of Oncology

Quantitative and qualitative characterization of plasma DNA identifies primary and recurrent colorectal cancer

(2008) M. Frattini et al.   CANCER LETTERS

Frequent mutations and amplifications of the PIK3CA gene in pituitary tumors

(2008) Yong Lin et al.   ENDOCRINE-RELATED CANCER

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Selective Loss ofMEG3Expression and Intergenic Differentially Methylated Region Hypermethylation in theMEG3/DLK1Locus in Human Clinically Nonfunctioning Pituitary Adenomas

(2008) Roger Gejman et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Euclidean and fractal geometry of microvascular networks in normal and neoplastic pituitary tissue

(2008) Antonio Di Ieva et al.   NEUROSURGICAL REVIEW

The concentration of deoxyribonucleic acid in plasma from 73 patients with colorectal cancer and apparent clinical correlations

(2008) Héctor Guadalajara et al.   Cancer Detection and Prevention