Molecular Network Basis of Invasive Pituitary Adenoma: A Review

ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway

(2018) Junwen Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Aggressive and malignant pituitary tumours: state-of-the-art

(2018) Dorota Dworakowska et al.   ENDOCRINE-RELATED CANCER

Caveolin-1 promotes pituitary adenoma cells migration and invasion by regulating the interaction between EGR1 and KLF5

(2018) Wei Yang et al.   EXPERIMENTAL CELL RESEARCH

Attenuation of EGFL7 Expression Inhibits Growth Hormone–Producing Pituitary Adenomas Growth and Invasion

(2018) Qian Liu et al.   HUMAN GENE THERAPY

Expression of the long non-coding RNA H19 and MALAT-1 in growth hormone-secreting pituitary adenomas and its relationship to tumor behavior

(2018) Tianyu Lu et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Down-regulation of TGF-β RII expression is correlated with tumor growth and invasion in non-functioning pituitary adenomas

(2018) Ying-hao Gu et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Aberrant expression of the sFRP and WIF1 genes in invasive non-functioning pituitary adenomas

(2018) Wang Song et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

VEGF–neuropilin-2 signaling promotes stem-like traits in breast cancer cells by TAZ-mediated repression of the Rac GAP β2-chimaerin

(2018) Ameer L. Elaimy et al.   Science Signaling

Relationship between expression of vascular endothelial growth factor and intratumoral hemorrhage in human pituitary adenomas

(2018) Young Jin Kim et al.   TUMORI

European Society of Endocrinology Clinical Practice Guidelines for the management of aggressive pituitary tumours and carcinomas

(2017) Gerald Raverot et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Relationship between RSUME and HIF-1α/VEGF-A with invasion of pituitary adenoma

(2017) Wei He et al.   GENE

EZH2 upregulation correlates with tumor invasiveness, proliferation, and angiogenesis in human pituitary adenomas

(2017) Bin Liu et al.   HUMAN PATHOLOGY

Long non-coding RNA C5orf66-AS1 is downregulated in pituitary null cell adenomas and is associated with their invasiveness

(2017) Guoqiang Yu et al.   ONCOLOGY REPORTS

Increased expression of the microRNA 106b~25 cluster and its host gene MCM7 in corticotroph pituitary adenomas is associated with tumor invasion and Crooke’s cell morphology

(2017) Filip Garbicz et al.   Pituitary

EGFL7 participates in regulating biological behavior of growth hormone–secreting pituitary adenomas via Notch2/DLL3 signaling pathway

(2017) Jianpeng Wang et al.   TUMOR BIOLOGY

Study on mirnas’ expression for the invasion of pituitary adenomas

(2017) Yu Guoqiang et al.   Turkish Neurosurgery

A Novel Invasive-Related Biomarker in Three Subtypes of Nonfunctioning Pituitary Adenomas

(2017) Yong Chen et al.   World Neurosurgery

Effect of miR-106b on Invasiveness of Pituitary Adenoma via PTEN-PI3K/AKT

(2017) Zhiming Zheng et al.   MEDICAL SCIENCE MONITOR

Connexin 43, breast cancer tumor suppressor: Missed connections?

(2016) Christina L. Grek et al.   CANCER LETTERS

miR-133 inhibits pituitary tumor cell migration and invasion via down-regulating FOXC1 expression

(2016) D.S. Wang et al.   GENETICS AND MOLECULAR RESEARCH

Metalloproteinases ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas

(2016) Junwen Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Combining Cadherin Expression with Molecular Markers Discriminates Invasiveness in Growth Hormone and Prolactin Pituitary Adenomas

(2016) N. Chauvet et al.   JOURNAL OF NEUROENDOCRINOLOGY

Matrix metalloproteinase-9 and -2 and tissue inhibitor of matrix metalloproteinase-2 in invasive pituitary adenomas

(2016) Hong-Yan Liu et al.   MEDICINE

Integrative proteomics and transcriptomics revealed that activation of the IL-6R/JAK2/STAT3/MMP9 signaling pathway is correlated with invasion of pituitary null cell adenomas

(2016) Jie Feng et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

HIF-1α Inhibition Sensitized Pituitary Adenoma Cells to Temozolomide by Regulating Presenilin 1 Expression and Autophagy

(2016) Zhang kun et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

Molecular markers in pituitary tumors

(2016) Asha M. Robertson et al.   Current Opinion in Endocrinology Diabetes and Obesity

Whole-exome sequencing identifies variants in invasive pituitary adenomas

(2016) Xiaolei Lan et al.   Oncology Letters

MiR-132, miR-15a and miR-16 synergistically inhibit pituitary tumor cell proliferation, invasion and migration by targeting Sox5

(2015) Wang Renjie et al.   CANCER LETTERS

β-catenin knockdown inhibits pituitary adenoma cell proliferation and invasion via interfering with AKT and gelatinases expression

(2015) CHENGCHENG ZHAO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-2: Prognostic biological markers in invasive prolactinomas

(2015) Güliz Demirelli Gültekin et al.   JOURNAL OF CLINICAL NEUROSCIENCE

VEGF-A modulates expression of inhibitory checkpoints on CD8+T cells in tumors

(2015) Thibault Voron et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Clinical Utility of TIMP3 Expression in ACTH-Secreting Pituitary Tumor

(2015) Bowen Sun et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Computational analysis identifies invasion-associated genes in pituitary adenomas

(2015) CHANGJUN CAO et al.   Molecular Medicine Reports

Disulfiram sensitizes pituitary adenoma cells to temozolomide by regulating O6-methylguanine-DNA methyltransferase expression

(2015) YACHAO ZHAO et al.   Molecular Medicine Reports

Histological criteria for atypical pituitary adenomas – data from the German pituitary adenoma registry suggests modifications

(2015) Christian P. Miermeister et al.   Acta Neuropathologica Communications

Relationship of PTTG Expression with Tumor Invasiveness and Microvessel Density of Pituitary Adenomas: A Meta-Analysis

(2014) Yan Li et al.   Genetic Testing and Molecular Biomarkers

Aggressive pituitary adenomas—diagnosis and emerging treatments

(2014) Antonio Di Ieva et al.   Nature Reviews Endocrinology

Effects of silencing connexin43 on expression of pituitary tumor-transforming gene in prolactinomas

(2014) Haitao Wang et al.   NEUROLOGICAL RESEARCH

Correlations of Vascular Architecture and Angiogenesis with Pituitary Adenoma Histotype

(2014) Shingo Takano et al.   International Journal of Endocrinology

Angiogenesis in Pituitary Adenomas: Human Studies and New Mutant Mouse Models

(2014) Carolina Cristina et al.   International Journal of Endocrinology

Silencing of HEPN1 is Responsible for the Aggressive Biological Behavior of Pituitary Somatotroph Adenomas

(2013) Hu Peng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Emerging Role of Connexin 43 in Testis Pathogenesis

(2013) D. Chevallier et al.   CURRENT MOLECULAR MEDICINE

Clinicopathological Investigation of Vascular Endothelial Growth Factor and von Hippel–Lindau Gene-Related Protein Expression in Immunohistochemically Negative Pituitary Adenoma – Possible Involvement in Tumor Aggressiveness

(2013) Yoshiteru Shimoda et al.   ENDOCRINE RESEARCH

Expression and Significance of E-Cadherin and β-Catenins in Pituitary Adenoma

(2013) Kaiyu Zhou et al.   INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY

The Role of Epigenetic Modification in Tumorigenesis and Progression of Pituitary Adenomas: A Systematic Review of the Literature

(2013) Matthew Pease et al.   PLoS One

Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition

(2013) M. Yu et al.   SCIENCE

Von Hippel-Lindau disease and aggressive GH-PRL pituitary adenoma in a young boy

(2012) Ancuta Tudorancea et al.   ANNALES D ENDOCRINOLOGIE

Connexin 43 a check-point component of cell proliferation implicated in a wide range of human testis diseases

(2012) Daniel Chevallier et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Gene Expression Profiling Identifies ESRP1 as a Potential Regulator of Epithelial Mesenchymal Transition in Somatotroph Adenomas from a Large Cohort of Patients with Acromegaly

(2012) Tove Lekva et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Curcumin suppresses HIF1A synthesis and VEGFA release in pituitary adenomas

(2012) B Shan et al.   JOURNAL OF ENDOCRINOLOGY

The pituitary tumour epigenome: aberrations and prospects for targeted therapy

(2012) Kiren Yacqub-Usman et al.   Nature Reviews Endocrinology

Over-expression of vascular endothelial growth factor in pituitary adenomas is associated with extrasellar growth and recurrence

(2012) Ruth Sánchez-Ortiga et al.   Pituitary

Cabergoline reduces cell viability in non functioning pituitary adenomas by inhibiting vascular endothelial growth factor secretion

(2012) Teresa Gagliano et al.   Pituitary

Pituitary tumor transforming gene induces epithelial to mesenchymal transition by regulation of Twist, Snail, Slug, and E-cadherin

(2011) Parag P. Shah et al.   CANCER LETTERS

The relationship between MRI invasive features and expression of EMMPRIN, galectin-3, and microvessel density in pituitary adenoma

(2011) Yinian Zhang et al.   CLINICAL IMAGING

RSUME is implicated in HIF-1-induced VEGF-A production in pituitary tumour cells

(2011) B Shan et al.   ENDOCRINE-RELATED CANCER

TNF-α-Induced VEGF and MMP-9 Expression Promotes Hemorrhagic Transformation in Pituitary Adenomas

(2011) Zhengzheng Xiao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In Nonfunctional Pituitary Adenomas, Estrogen Receptors and Slug Contribute to Development of Invasiveness

(2011) Wei Zhou et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Inhibitory Effects of Antivascular Endothelial Growth Factor Strategies in Experimental Dopamine-Resistant Prolactinomas

(2011) G. M. Luque et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

PTTG induces EMT through integrin αVβ3-focal adhesion kinase signaling in lung cancer cells

(2011) P P Shah et al.   ONCOGENE

Hypoxia induces hemorrhagic transformation in pituitary adenomas via the HIF-1α signaling pathway

(2011) Ting Lei   ONCOLOGY REPORTS

The expression of interleukin (IL)-17 and IL-17 receptor and MMP-9 in human pituitary adenomas

(2011) Lubin Qiu et al.   Pituitary

The effect of polymorphisms in the promoter region of the MMP-1 gene on the occurrence and invasiveness of hypophyseal adenoma

(2010) Murat Altaş et al.   ACTA NEUROCHIRURGICA

Signaling pathway networks mined from human pituitary adenoma proteomics data

(2010) Xianquan Zhan et al.   BMC Medical Genomics

Gap junctions and connexins as therapeutic targets in cancer

(2010) Mustapha Kandouz et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

CD147 expression in pituitary adenomas and its significance for clinical outcome

(2010) Xin Qu et al.   HUMAN PATHOLOGY

Prognostic Factors in Prolactin Pituitary Tumors: Clinical, Histological, and Molecular Data from a Series of 94 Patients with a Long Postoperative Follow-Up

(2010) Gérald Raverot et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The expression of integrinβ1 and FAK in pituitary adenomas and their correlation with invasiveness

(2010) Feng Wang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Pituitary senescence: The evolving role of Pttg

(2010) Vera Chesnokova et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Curcumin Inhibits the Growth, Induces Apoptosis and Modulates the Function of Pituitary Folliculostellate Cells

(2010) Christian Schaaf et al.   NEUROENDOCRINOLOGY

Nuclear Accumulation of E-Cadherin Correlates with Loss of Cytoplasmic Membrane Staining and Invasion in Pituitary Adenomas

(2009) Marianne S. Elston et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Regulation of cell invasion and signalling pathways in the pituitary adenoma cell line, HP-75, by reversion-inducing cysteine-rich protein with kazal motifs (RECK)

(2008) Daizo Yoshida et al.   JOURNAL OF NEURO-ONCOLOGY