Aromatic Herbs, Medicinal Plant-Derived Essential Oils, and Phytochemical Extracts as Potential Therapies for Coronaviruses: Future Perspectives

The deadly coronaviruses: The 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China

(2020) Yongshi Yang et al.   JOURNAL OF AUTOIMMUNITY

More than 80 clinical trials launch to test coronavirus treatments

(2020) Amy Maxmen   NATURE

COVID-19 and the cardiovascular system

(2020) Ying-Ying Zheng et al.   Nature Reviews Cardiology

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antiviral Action of Tryptanthrin Isolated from Strobilanthes cusia Leaf against Human Coronavirus NL63

(2020) Yu-Chi Tsai et al.   Biomolecules

Inhibitory Effects of Myricetin on Lipopolysaccharide-Induced Neuroinflammation

(2020) Jung-Hee Jang et al.   Brain Sciences

Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event

(2020) D. Paraskevis et al.   INFECTION GENETICS AND EVOLUTION

Clinical features and treatment of COVID-19 patients in northeast Chongqing

(2020) Suxin Wan et al.   JOURNAL OF MEDICAL VIROLOGY

Advances on Antiviral Activity of Morus spp. Plant Extracts: Human Coronavirus and Virus-Related Respiratory Tract Infections in the Spotlight

(2020) Inès Thabti et al.   MOLECULES

Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2

(2020) Yadi Zhou et al.   Cell Discovery

Viral dynamics in mild and severe cases of COVID-19

(2020) Yang Liu et al.   LANCET INFECTIOUS DISEASES

COVID-19: A promising cure for the global panic

(2020) Balachandar Vellingiri et al.   SCIENCE OF THE TOTAL ENVIRONMENT

High-throughput Screening and Identification of Potent Broad-spectrum Inhibitors of Coronaviruses

(2019) Liang Shen et al.   JOURNAL OF VIROLOGY

Novel anti-obesity effect of scutellarein and potential underlying mechanism of actions

(2019) Yiguang Lin et al.   BIOMEDICINE & PHARMACOTHERAPY

Antiviral activity of Sambucus FormosanaNakai ethanol extract and related phenolic acid constituents against human coronavirus NL63

(2019) Jing-Ru Weng et al.   VIRUS RESEARCH

Antiviral Activity Against Infectious Bronchitis Virus and Bioactive Components of Hypericum perforatum L.

(2019) Huijie Chen et al.   Frontiers in Pharmacology

Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung Cells

(2019) Kim et al.   Biomolecules

Saikosaponins: a review of pharmacological effects

(2018) Xiao-Qin Li et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Evaluation of polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors

(2017) Ji-Young Park et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors

(2016) Vathan Kumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Approved Antiviral Drugs over the Past 50 Years

(2016) Erik De Clercq et al.   CLINICAL MICROBIOLOGY REVIEWS

Discovery, diversity and evolution of novel coronaviruses sampled from rodents in China

(2015) Wen Wang et al.   VIROLOGY

Bat origin of human coronaviruses

(2015) Ben Hu et al.   Virology Journal

Sambucus nigra extracts inhibit infectious bronchitis virus at an early point during replication

(2014) Christie Chen et al.   BMC Veterinary Research

From SARS to MERS: 10 years of research on highly pathogenic human coronaviruses

(2013) Rolf Hilgenfeld et al.   ANTIVIRAL RESEARCH

Phenolic phytochemical displaying SARS-CoV papain-like protease inhibition from the seeds ofPsoralea corylifolia

(2013) Dae Wook Kim et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Quercetin inhibits rhinovirus replication in vitro and in vivo

(2012) Shyamala Ganesan et al.   ANTIVIRAL RESEARCH

Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases

(2012) Ji-Young Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13

(2012) Mi-Sun Yu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Licochalcone A Inhibits Lipopolysaccharide-Induced Inflammatory Response in Vitro and in Vivo

(2012) Xiao Chu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of analgesic, anti-inflammatory and hepatoprotective effects of lycorine from Sternbergia fisheriana (Herbert) Rupr.

(2011) G. Saltan Çitoğlu et al.   FITOTERAPIA

Ruscogenin inhibits lipopolysaccharide-induced acute lung injury in mice: Involvement of tissue factor, inducible NO synthase and nuclear factor (NF)-κB

(2011) Qi Sun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Medicinal herbal extracts of Sophorae radix, Acanthopanacis cortex, Sanguisorbae radix and Torilis fructus inhibit coronavirus replication in vitro

(2010) Hye-Young Kim et al.   ANTIVIRAL THERAPY

Biflavonoids from Torreya nucifera displaying SARS-CoV 3CLpro inhibition

(2010) Young Bae Ryu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The changing epidemiology of type 1 diabetes: why is it going through the roof?

(2010) Kendra Vehik et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Investigation of the influence of EPs® 7630, a herbal drug preparation from Pelargonium sidoides, on replication of a broad panel of respiratory viruses

(2010) Martin Michaelis et al.   PHYTOMEDICINE

Antiinflammatory effects in THP-1 cells treated with verbascoside

(2010) Lorenza Speranza et al.   PHYTOTHERAPY RESEARCH

Procyanidins and butanol extract of Cinnamomi Cortex inhibit SARS-CoV infection

(2009) Min Zhuang et al.   ANTIVIRAL RESEARCH

In Vivo and in Vitro Antiviral Activities of Calycosin-7-O-β-D-glucopyranoside against Coxsackie Virus B3

(2009) Haiyan Zhu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

(2009) B. R. O'Keefe et al.   JOURNAL OF VIROLOGY

Structural Flexibility of the Pentameric SARS Coronavirus Envelope Protein Ion Channel

(2008) Krupakar Parthasarathy et al.   BIOPHYSICAL JOURNAL

Phytochemical Analysis andin vitro Antiviral Activities of the Essential Oils of Seven Lebanon Species

(2008) Monica R. Loizzo et al.   CHEMISTRY & BIODIVERSITY

Therapy of chronic hepatitis B: trends and developments

(2008) W DELANEYIV et al.   CURRENT OPINION IN PHARMACOLOGY

The Antiherpetic Drug Acyclovir Inhibits HIV Replication and Selects the V75I Reverse Transcriptase Multidrug Resistance Mutation

(2008) Moira A. McMahon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunomodulatory and anti-SARS activities of Houttuynia cordata

(2008) Kit-Man Lau et al.   JOURNAL OF ETHNOPHARMACOLOGY

Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants

(2008) Patrick J. Collins et al.   NATURE

In vitro inhibition of coronavirus replications by the traditionally used medicinal herbal extracts, Cimicifuga rhizoma, Meliae cortex, Coptidis rhizoma, and Phellodendron cortex

(2007) Hye-Young Kim et al.   JOURNAL OF CLINICAL VIROLOGY