An Integrated Spatial Dynamics—Pharmacokinetic Model Explaining Poor Penetration of Anti-retroviral Drugs in Lymph Nodes

High-Speed Single-Molecule Tracking of CXCL13 in the B-Follicle

(2018) Helen Miller et al.   Frontiers in Immunology

Persistent HIV-1 replication maintains the tissue reservoir during therapy

(2016) Ramon Lorenzo-Redondo et al.   NATURE

Antiretroviral Therapy

(2014) Alice K. Pau et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Spatial modeling of HIV cryptic viremia and 2-LTR formation during raltegravir intensification

(2014) E. Fabian Cardozo et al.   JOURNAL OF THEORETICAL BIOLOGY

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

(2014) Courtney V. Fletcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling the within-host dynamics of HIV infection

(2013) Alan S Perelson et al.   BMC BIOLOGY

Modelling HIV-1 2-LTR dynamics following raltegravir intensification

(2013) R. Luo et al.   Journal of the Royal Society Interface

HIV-1 Antiretroviral Drug Therapy

(2013) E. J. Arts et al.   Cold Spring Harbor Perspectives in Medicine

Population Pharmacokinetic Analysis and Pharmacogenetics of Raltegravir in HIV-Positive and Healthy Individuals

(2012) Mona Arab-Alameddine et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

HIV Model Parameter Estimates from Interruption Trial Data including Drug Efficacy and Reservoir Dynamics

(2012) Rutao Luo et al.   PLoS One

Absence of HIV-1 Evolution in the Gut-Associated Lymphoid Tissue from Patients on Combination Antiviral Therapy Initiated during Primary Infection

(2012) Teresa H. Evering et al.   PLoS Pathogens

Plasma and Intracellular Population Pharmacokinetic Analysis of Tenofovir in HIV-1-Infected Patients

(2011) Gautam Baheti et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetic Modeling of Plasma and Intracellular Concentrations of Raltegravir in Healthy Volunteers

(2011) Lingzhi Wang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cell disposition of raltegravir and newer antiretrovirals in HIV-infected patients: high inter-individual variability in raltegravir cellular penetration

(2011) A. Fayet Mello et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Systems biology approaches for understanding cellular mechanisms of immunity in lymph nodes during infection

(2011) Henry P. Mirsky et al.   JOURNAL OF THEORETICAL BIOLOGY

Clonal Sequences Recovered from Plasma from Patients with Residual HIV-1 Viremia and on Intensified Antiretroviral Therapy Are Identical to Replicating Viral RNAs Recovered from Circulating Resting CD4+ T Cells

(2011) J. A. Anderson et al.   JOURNAL OF VIROLOGY

A model of partial differential equations for HIV propagation in lymph nodes

(2011) E.B.S. Marinho et al.   PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS

HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects

(2010) Maria J Buzón et al.   NATURE MEDICINE

Antiretroviral Tissue Kinetics: In Vivo Imaging Using Positron Emission Tomography

(2009) M. Di Mascio et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Modeling lymphocyte homing and encounters in lymph nodes

(2009) Valentina Baldazzi et al.   BMC BIOINFORMATICS

Viral Sanctuaries during Highly Active Antiretroviral Therapy in a Nonhuman Primate Model for AIDS

(2009) T. W. North et al.   JOURNAL OF VIROLOGY

Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node

(2008) Friederike Pfeiffer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antiretroviral Treatment of Adult HIV Infection

(2008) Scott M. Hammer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs

(2008) Lin Shen et al.   NATURE MEDICINE