New Understanding of the Relevant Role of LINE-1 Retrotransposition in Human Disease and Immune Modulation
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Title
New Understanding of the Relevant Role of LINE-1 Retrotransposition in Human Disease and Immune Modulation
Authors
Keywords
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Journal
Frontiers in Cell and Developmental Biology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-08-07
DOI
10.3389/fcell.2020.00657
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Note: Only part of the references are listed.- Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
- (2020) Bernardo Rodriguez-Martin et al. NATURE GENETICS
- Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity
- (2020) Marla E. Tharp et al. Nature Communications
- Soy Isoflavone Supplementation Increases Long Interspersed Nucleotide Element-1 (LINE-1) Methylation in Head and Neck Squamous Cell Carcinoma
- (2019) Laura S. Rozek et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Tumor Long-interspersed Nucleotide Element-1 Methylation Level and Immune Response to Esophageal Cancer
- (2019) Keisuke Kosumi et al. ANNALS OF SURGERY
- A phase 1 trial of the oral DNA methyltransferase inhibitor CC‐486 and the histone deacetylase inhibitor romidepsin in advanced solid tumors
- (2019) Stéphanie L. Gaillard et al. CANCER
- Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication
- (2019) Diane A. Flasch et al. CELL
- miR-128 Restriction of LINE-1 (L1) Retrotransposition Is Dependent on Targeting hnRNPA1 mRNA
- (2019) Lianna Fung et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Landscape of L1 Retrotransposons in the Human Genome Is Shaped by Pre-insertion Sequence Biases and Post-insertion Selection
- (2019) Tania Sultana et al. MOLECULAR CELL
- Investigation of lipid metabolism dysregulation and the effects on immune microenvironments in pan-cancer using multiple omics data
- (2019) Yang Hao et al. BMC BIOINFORMATICS
- LINE-1 Retrotransposition Promotes the Development and Progression of Lung Squamous Cell Carcinoma by Disrupting the Tumor Suppressor Gene FGGY
- (2019) Rui Zhang et al. CANCER RESEARCH
- Long interspersed nuclear element-1 mobilization as a target in cancer diagnostics, prognostics and therapeutics
- (2019) Afsaneh Lavasanifar et al. CLINICA CHIMICA ACTA
- Proteome Profile of Endogenous Retrotransposon‐Associated Complexes in Human Embryonic Stem Cells
- (2019) Linh M. Vuong et al. PROTEOMICS
- Correlation of long interspersed element-1 open reading frame 1 and c-Met proto-oncogene protein expression in ovarian cancer
- (2019) Eun-Ji Ko et al. Genes & Genomics
- Transposable elements in human genetic disease
- (2019) Lindsay M. Payer et al. NATURE REVIEWS GENETICS
- A re-evaluation of LINE-1 ORF2 expression in LNCaP prostate cancer cells
- (2019) Erica M. Briggs et al. Mobile DNA
- LINE-1 ORF2p expression is nearly imperceptible in human cancers
- (2019) Daniel Ardeljan et al. Mobile DNA
- Transposable element activity, genome regulation and human health
- (2018) Lu Wang et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Long Interspersed Element-1 Methylation Level as a Prognostic Biomarker in Gastrointestinal Cancers
- (2018) Yoshifumi Baba et al. DIGESTION
- LINE-1-encoded reverse Transcriptase as a target in cancer therapy
- (2018) Corrado Spadafora Frontiers in Bioscience-Landmark
- LINE-1 activity and regulation in cancer
- (2018) Nemanja Rodic Frontiers in Bioscience-Landmark
- Immune signatures correlate with L1 retrotransposition in gastrointestinal cancers
- (2018) Hyunchul Jung et al. GENOME RESEARCH
- LINE1 contributes to autoimmunity through both RIG-I- and MDA5-mediated RNA sensing pathways
- (2018) Ke Zhao et al. JOURNAL OF AUTOIMMUNITY
- LINE-1: IMPLICATIONS IN THE ETIOLOGY OF CANCER, CLINICAL APPLICATIONS, AND PHARMACOLOGIC TARGETS
- (2018) M Khalid et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Histone Demethylase KDM4B Promotes DNA Damage by Activating Long Interspersed Nuclear Element-1
- (2018) Ying Xiang et al. CANCER RESEARCH
- Discovery of the Long Interspersed Nuclear Element-1 activation product [Open Reading Frame-1 (ORF1) protein] in human blood
- (2018) Keivan Hosseinnejad et al. CLINICA CHIMICA ACTA
- Inhibition of LINE-1 Retrotransposition by Capsaicin
- (2018) Yuki Nishikawa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Hypomethylation of LINE-1 elements in schizophrenia and bipolar disorder
- (2018) Shufen Li et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition
- (2017) Claiborne M. Christian et al. GENETICS
- MicroRNA miR-128 represses LINE-1 (L1) retrotransposition by down-regulating the nuclear import factor TNPO1
- (2017) Adam Idica et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Anticancer Activity of Natural and Synthetic Capsaicin Analogs
- (2017) Jamie R. Friedman et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- LINE-1 Hypermethylation in Serum Cell-Free DNA of Relapsing Remitting Multiple Sclerosis Patients
- (2017) Marina Dunaeva et al. MOLECULAR NEUROBIOLOGY
- Mobile DNA in Health and Disease
- (2017) Haig H. Kazazian et al. NEW ENGLAND JOURNAL OF MEDICINE
- Oxidative stress, inflammation and treatment response in major depression
- (2017) Daniel Lindqvist et al. PSYCHONEUROENDOCRINOLOGY
- Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition
- (2017) Claiborne M. Christian et al. GENETICS
- Genome-wide characterization of human L1 antisense promoter-driven transcripts
- (2016) Steven W. Criscione et al. BMC GENOMICS
- LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
- (2016) Almut Brand et al. Cell Metabolism
- The impact of transposable elements on mammalian development
- (2016) Jose L. Garcia-Perez et al. DEVELOPMENT
- Carboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label KEYNOTE-021 study
- (2016) Corey J Langer et al. LANCET ONCOLOGY
- Roles for retrotransposon insertions in human disease
- (2016) Dustin C. Hancks et al. Mobile DNA
- Expression of Long Interspersed Nuclear Element 1 Retroelements and Induction of Type I Interferon in Patients With Systemic Autoimmune Disease
- (2016) Clio P. Mavragani et al. Arthritis & Rheumatology
- Upregulated LINE-1 Activity in the Fanconi Anemia Cancer Susceptibility Syndrome Leads to Spontaneous Pro-inflammatory Cytokine Production
- (2016) Christelle Brégnard et al. EBioMedicine
- Inverse changes in L1 retrotransposons between blood and brain in major depressive disorder
- (2016) Shu Liu et al. Scientific Reports
- Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
- (2015) Katherine B. Chiappinelli et al. CELL
- Primate-Specific ORF0 Contributes to Retrotransposon-Mediated Diversity
- (2015) Ahmet M. Denli et al. CELL
- Patterns and functional roles of LINE-1 and Alu methylation in the keratinocyte from patients with psoriasis vulgaris
- (2015) Surasak Yooyongsatit et al. JOURNAL OF HUMAN GENETICS
- miR-128 represses L1 retrotransposition by binding directly to L1 RNA
- (2015) Matthias Hamdorf et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- miR-128 represses L1 retrotransposition by binding directly to L1 RNA
- (2015) Matthias Hamdorf et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformation
- (2015) Chiara De Luca et al. Oncotarget
- Crossing the LINE Toward Genomic Instability: LINE-1 Retrotransposition in Cancer
- (2015) Jacqueline R. Kemp et al. Frontiers in Chemistry
- The novel Aryl hydrocarbon receptor inhibitor biseugenol inhibits gastric tumor growth and peritoneal dissemination
- (2015) De-Wei Lai et al. Oncotarget
- Long Interspersed Element-1 Protein Expression Is a Hallmark of Many Human Cancers
- (2014) Nemanja Rodić et al. AMERICAN JOURNAL OF PATHOLOGY
- Chromosomal Instability Associated with Global DNA Hypomethylation is Associated with the Initiation and Progression of Esophageal Squamous Cell Carcinoma
- (2014) Hiroyuki Kawano et al. ANNALS OF SURGICAL ONCOLOGY
- LINE-1 Hypomethylation, DNA Copy Number Alterations, andCDK6Amplification in Esophageal Squamous Cell Carcinoma
- (2014) Yoshifumi Baba et al. CLINICAL CANCER RESEARCH
- Type 2 diabetes mellitus in relation to global LINE-1 DNA methylation in peripheral blood: A cohort study
- (2014) Gracia María Martín-Núñez et al. Epigenetics
- Transportin-1 and Transportin-2: Protein nuclear import and beyond
- (2014) Laure Twyffels et al. FEBS LETTERS
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Adenoma Detection Rate and Risk of Colorectal Cancer and Death
- (2014) NEW ENGLAND JOURNAL OF MEDICINE
- Potential for genomic instability associated with retrotranspositionally-incompetent L1 loci
- (2014) Kristine J. Kines et al. NUCLEIC ACIDS RESEARCH
- A Phase II Trial Evaluating the Efficacy and Safety of Efavirenz in Metastatic Castration-Resistant Prostate Cancer
- (2014) N. Houede et al. ONCOLOGIST
- LINE-1 Hypomethylation in Blood and Tissue Samples as an Epigenetic Marker for Cancer Risk: A Systematic Review and Meta-Analysis
- (2014) Martina Barchitta et al. PLoS One
- SVA retrotransposon insertion-associated deletion represents a novel mutational mechanism underlying large genomic copy number changes with non-recurrent breakpoints
- (2014) Julia Vogt et al. GENOME BIOLOGY
- Epigenetic Potentiation of NY-ESO-1 Vaccine Therapy in Human Ovarian Cancer
- (2014) K. Odunsi et al. Cancer Immunology Research
- Genes associated with the cis-regulatory functions of intragenic LINE-1 elements
- (2013) Wachiraporn Wanichnopparat et al. BMC GENOMICS
- Early Diagnostic Biomarkers for Esophageal Adenocarcinoma--The Current State of Play
- (2013) A. K. Shah et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells
- (2013) Z. Husain et al. JOURNAL OF IMMUNOLOGY
- Reprogramming of the HepG2 genome by long interspersed nuclear element-1
- (2013) Pasano Bojang et al. Molecular Oncology
- Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition
- (2013) John L. Goodier et al. NUCLEIC ACIDS RESEARCH
- Long Interspersed Element–1 (LINE-1): Passenger or Driver in Human Neoplasms?
- (2013) Nemanja Rodić et al. PLoS Genetics
- LINE-1 Hypomethylation Is Associated With a Poor Prognosis Among Patients With Curatively Resected Esophageal Squamous Cell Carcinoma
- (2012) Shiro Iwagami et al. ANNALS OF SURGERY
- LINE-1 hypomethylation in gastric cancer, detected by bisulfite pyrosequencing, is associated with poor prognosis
- (2012) Hironobu Shigaki et al. Gastric Cancer
- Global LINE-1 DNA methylation is associated with blood glycaemic and lipid profiles
- (2012) Mark S Pearce et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Evolution of HLA-DRB Genes
- (2012) Gaby G.M. Doxiadis et al. MOLECULAR BIOLOGY AND EVOLUTION
- Transposable Elements in TDP-43-Mediated Neurodegenerative Disorders
- (2012) Wanhe Li et al. PLoS One
- LINE-1 methylation in visceral adipose tissue of severely obese individuals is associated with metabolic syndrome status and related phenotypes
- (2012) Valérie Turcot et al. Clinical Epigenetics
- Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
- (2011) Sophia Y. Lunt et al. Annual Review of Cell and Developmental Biology
- LINE-1 Elements in Structural Variation and Disease
- (2011) Christine R. Beck et al. Annual Review of Genomics and Human Genetics
- Modulation of Cell Differentiation, Proliferation, and Tumor Growth by Dihydrobenzyloxopyrimidine Non-Nucleoside Reverse Transcriptase Inhibitors
- (2011) Gianluca Sbardella et al. JOURNAL OF MEDICINAL CHEMISTRY
- Hypomethylation of Intragenic LINE-1 Represses Transcription in Cancer Cells through AGO2
- (2011) Chatchawit Aporntewan et al. PLoS One
- Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells
- (2011) N. G. Coufal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The FGGY Carbohydrate Kinase Family: Insights into the Evolution of Functional Specificities
- (2011) Ying Zhang et al. PLoS Computational Biology
- The NF1 Gene Contains Hotspots for L1 Endonuclease-Dependent De Novo Insertion
- (2011) Katharina Wimmer et al. PLoS Genetics
- Repetitive Elements May Comprise Over Two-Thirds of the Human Genome
- (2011) A. P. Jason de Koning et al. PLoS Genetics
- Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects
- (2010) Li Wang et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Long Interspersed Nuclear Element 1 Hypomethylation Is a Marker of Poor Prognosis in Stage IA Non-Small Cell Lung Cancer
- (2010) K. Saito et al. CLINICAL CANCER RESEARCH
- Mosaic type-1 NF1 microdeletions as a cause of both generalized and segmental neurofibromatosis type-1 (NF1)
- (2010) Ludwine Messiaen et al. HUMAN MUTATION
- L1 retrotransposition in neurons is modulated by MeCP2
- (2010) Alysson R. Muotri et al. NATURE
- Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription
- (2010) B Weber et al. ONCOGENE
- The Reverse Transcription Inhibitor Abacavir Shows Anticancer Activity in Prostate Cancer Cell Lines
- (2010) Francesca Carlini et al. PLoS One
- The impact of retrotransposons on human genome evolution
- (2009) Richard Cordaux et al. NATURE REVIEWS GENETICS
- A Cohort Study of Tumoral LINE-1 Hypomethylation and Prognosis in Colon Cancer
- (2008) Shuji Ogino et al. JNCI-Journal of the National Cancer Institute
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