Lipid Exchangers: Cellular Functions and Mechanistic Links With Phosphoinositide Metabolism

pH Biosensing by PI4P Regulates Cargo Sorting at the TGN

(2020) John J.H. Shin et al.   DEVELOPMENTAL CELL

Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane

(2020) James P. Zewe et al.   JOURNAL OF CELL BIOLOGY

Defining the subcellular distribution and metabolic channeling of phosphatidylinositol

(2020) Joshua G. Pemberton et al.   JOURNAL OF CELL BIOLOGY

ORP3 phosphorylation regulates phosphatidylinositol 4-phosphate and Ca2+ dynamics at PM-ER contact sites

(2020) Gergő Gulyás et al.   JOURNAL OF CELL SCIENCE

Noncanonical regulation of phosphatidylserine metabolism by a Sec14-like protein and a lipid kinase

(2020) Yaxi Wang et al.   JOURNAL OF CELL BIOLOGY

Osh6 requires Ist2 for localization to the ER-PM contacts and efficient phosphatidylserine transport

(2020) Juan Martín D'Ambrosio et al.   JOURNAL OF CELL SCIENCE

Oxysterol-binding protein-related protein 1 variants have opposing cholesterol transport activities from the endolysosomes

(2020) Kexin Zhao et al.   MOLECULAR BIOLOGY OF THE CELL

Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex

(2020) Ryan S D'Souza et al.   eLife

Ca2+ signaling and lipid transfer ‘pas a deux’ at ER-PM contact sites orchestrate cell migration

(2020) Khaled Machaca   CELL CALCIUM

Molecular determinants of ER–Golgi contacts identified through a new FRET–FLIM system

(2019) Rossella Venditti et al.   JOURNAL OF CELL BIOLOGY

The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity

(2019) Patricia Gómez-Suaga et al.   Acta Neuropathologica Communications

ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells

(2019) Wenbin Zhong et al.   Cell Reports

Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2

(2019) Jiangqing Dong et al.   Nature Communications

Suppression of respiratory growth defect of mitochondrial phosphatidylserine decarboxylase deficient mutant by overproduction of Sfh1, a Sec14 homolog, in yeast

(2019) Aya Mizuike et al.   PLoS One

Nir2 is an effector of VAPs necessary for efficient HCV replication and PI(4)P enrichment at the viral replication organelle

(2019) Hongliang Wang et al.   JOURNAL OF VIROLOGY

Osh Proteins Control Nanoscale Lipid Organization Necessary for PI(4,5)P2 Synthesis

(2019) Taki Nishimura et al.   MOLECULAR CELL

ER–lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann–Pick type C

(2019) Chun-Yan Lim et al.   NATURE CELL BIOLOGY

Tricalbins Contribute to Cellular Lipid Flux and Form Curved ER-PM Contacts that Are Bridged by Rod-Shaped Structures

(2019) Patrick C. Hoffmann et al.   DEVELOPMENTAL CELL

Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity

(2019) Javier Collado et al.   DEVELOPMENTAL CELL

Functional diversification of the chemical landscapes of yeast Sec14-like phosphatidylinositol transfer protein lipid-binding cavities

(2019) Ashutosh Tripathi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ORP5 localizes to ER–lipid droplet contacts and regulates the level of PI(4)P on lipid droplets

(2019) Ximing Du et al.   JOURNAL OF CELL BIOLOGY

The functional universe of membrane contact sites

(2019) William A. Prinz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An electrostatic switching mechanism to control the lipid transfer activity of Osh6p

(2019) Nicolas-Frédéric Lipp et al.   Nature Communications

Retrospective on Cholesterol Homeostasis: The Central Role of Scap

(2018) Michael S. Brown et al.   Annual Review of Biochemistry

Both the PH domain and N-terminal region of oxysterol-binding protein related protein 8S are required for localization to PM-ER contact sites

(2018) Minhyoung Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism

(2018) Henriikka Kentala et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis

(2018) Zhigang Xie et al.   DEVELOPMENTAL CELL

Oxysterol-binding protein–related protein 5 (ORP5) promotes cell proliferation by activation of mTORC1 signaling

(2018) Ximing Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoinositide binding by the PH domain in ceramide transfer protein (CERT) is inhibited by hyperphosphorylation of an adjacent serine-repeat motif

(2018) Toshihiko Sugiki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PI(4,5)P2controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites

(2018) Mira Sohn et al.   JOURNAL OF CELL BIOLOGY

The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution

(2018) Tomoaki Sobajima et al.   JOURNAL OF CELL BIOLOGY

Golgi localization of oxysterol binding protein-related protein 4L (ORP4L) is regulated by ligand binding

(2018) Antonietta Pietrangelo et al.   JOURNAL OF CELL SCIENCE

Model of OSBP-Mediated Cholesterol Supply to Aichi Virus RNA Replication Sites Involving Protein-Protein Interactions among Viral Proteins, ACBD3, OSBP, VAP-A/B, and SAC1

(2018) Kumiko Ishikawa-Sasaki et al.   JOURNAL OF VIROLOGY

OSBP-related protein 4L promotes phospholipase Cβ3 translocation from the nucleus to the plasma membrane in Jurkat T-cells

(2018) Guoping Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gating mechanism of the extracellular entry to the lipid pathway in a TMEM16 scramblase

(2018) Byoung-Cheol Lee et al.   Nature Communications

Biophysical Parameters of the Sec14 Phospholipid Exchange Cycle

(2018) Taichi Sugiura et al.   BIOPHYSICAL JOURNAL

Organelle contact zones as sites for lipid transfer

(2018) Yasushi Tamura et al.   JOURNAL OF BIOCHEMISTRY

ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2)

(2018) Huan Wang et al.   MOLECULAR CELL

In vitro lipid transfer assays of phosphatidylinositol transfer proteins provide insight into the in vivo mechanism of ligand transfer

(2018) Candace Panagabko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Lipid exchange and signaling at ER–Golgi contact sites

(2018) Bruno Mesmin et al.   CURRENT OPINION IN CELL BIOLOGY

Interaction between the PH and START domains of ceramide transfer protein competes with phosphatidylinositol 4-phosphate binding by the PH domain

(2017) Jennifer Prashek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid-dependent regulation of exocytosis inS. cerevisiaeby OSBP homolog (Osh) 4

(2017) Richard J. Smindak et al.   JOURNAL OF CELL SCIENCE

Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction

(2017) Mohammad Kawsar Manik et al.   STRUCTURE

Advances on the Transfer of Lipids by Lipid Transfer Proteins

(2017) Louise H. Wong et al.   TRENDS IN BIOCHEMICAL SCIENCES

ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane

(2017) Rajesh Ghai et al.   Nature Communications

Oxysterol-Binding Protein-Related Protein 1L Regulates Cholesterol Egress from the Endo-Lysosomal System

(2017) Kexin Zhao et al.   Cell Reports

Running up that hill: How to create cellular lipid gradients by lipid counter-flows

(2016) Joachim Moser von Filseck et al.   BIOCHIMIE

PITPNC1 Recruits RAB1B to the Golgi Network to Drive Malignant Secretion

(2016) Nils Halberg et al.   CANCER CELL

Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P

(2016) Rui Dong et al.   CELL

ORP4L Facilitates Macrophage Survival via G-Protein–Coupled SignalingNovelty and Significance

(2016) Wenbin Zhong et al.   CIRCULATION RESEARCH

Annexin A1 Tethers Membrane Contact Sites that Mediate ER to Endosome Cholesterol Transport

(2016) Emily R. Eden et al.   DEVELOPMENTAL CELL

ORP5/ORP8 localize to endoplasmic reticulum–mitochondria contacts and are involved in mitochondrial function

(2016) Romain Galmes et al.   EMBO REPORTS

Features of the Phosphatidylinositol Cycle and its Role in Signal Transduction

(2016) Richard M. Epand   JOURNAL OF MEMBRANE BIOLOGY

Oxysterol-related-binding-protein related Protein-2 (ORP2) regulates cortisol biosynthesis and cholesterol homeostasis

(2016) Tamara Escajadillo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Lenz-Majewski mutations inPTDSS1affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions

(2016) Mira Sohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The orchestra of lipid-transfer proteins at the crossroads between metabolism and signaling

(2016) Antonella Chiapparino et al.   PROGRESS IN LIPID RESEARCH

ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival

(2016) Wenbin Zhong et al.   Nature Communications

Broad-range inhibition of enterovirus replication by OSW-1, a natural compound targeting OSBP

(2015) Lucian Albulescu et al.   ANTIVIRAL RESEARCH

Phosphatidylinositol-Phosphatidic Acid Exchange by Nir2 at ER-PM Contact Sites Maintains Phosphoinositide Signaling Competence

(2015) Yeun Ju Kim et al.   DEVELOPMENTAL CELL

OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity

(2015) Marion Weber-Boyvat et al.   EXPERIMENTAL CELL RESEARCH

Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors

(2015) KAZUYA NAGANO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Phosphatidylinositol 4,5-Bisphosphate Homeostasis Regulated by Nir2 and Nir3 Proteins at Endoplasmic Reticulum-Plasma Membrane Junctions

(2015) Chi-Lun Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RDGB , a PtdIns-PtdOH transfer protein, regulates G-protein-coupled PtdIns(4,5)P2 signalling during Drosophila phototransduction

(2015) S. Yadav et al.   JOURNAL OF CELL SCIENCE

Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor

(2015) Monika Christen et al.   JOURNAL OF STRUCTURAL BIOLOGY

Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate

(2015) J. Moser von Filseck et al.   SCIENCE

PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts

(2015) J. Chung et al.   SCIENCE

A phosphatidylinositol-4-phosphate powered exchange mechanism to create a lipid gradient between membranes

(2015) Joachim Moser von Filseck et al.   Nature Communications

Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein

(2015) Jeroen R.P.M. Strating et al.   Cell Reports

Topological Regulation of Lipid Balance in Cells

(2014) Guillaume Drin   Annual Review of Biochemistry

Phosphatidylinositol binding of Saccharomyces cerevisiae Pdr16p represents an essential feature of this lipid transfer protein to provide protection against azole antifungals

(2014) Roman Holič et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Rhinovirus Uses a Phosphatidylinositol 4-Phosphate/Cholesterol Counter-Current for the Formation of Replication Compartments at the ER-Golgi Interface

(2014) Pascal S. Roulin et al.   Cell Host & Microbe

Ligand-dependent localization and function of ORP–VAP complexes at membrane contact sites

(2014) Marion Weber-Boyvat et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Oxysterol-Binding Protein Is a Phosphatidylinositol 4-Kinase Effector Required for HCV Replication Membrane Integrity and Cholesterol Trafficking

(2014) Hongliang Wang et al.   GASTROENTEROLOGY

Oxysterol-binding Protein (OSBP)-related Protein 4 (ORP4) Is Essential for Cell Proliferation and Survival

(2014) Mark Charman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi

(2014) Gerald R.V. Hammond et al.   JOURNAL OF CELL BIOLOGY

A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress–induced membrane biogenesis

(2014) Jihui Ren et al.   MOLECULAR BIOLOGY OF THE CELL

Osh4p is needed to reduce the level of phosphatidylinositol-4-phosphate on secretory vesicles as they mature

(2014) Yading Ling et al.   MOLECULAR BIOLOGY OF THE CELL

X-ray structure of a calcium-activated TMEM16 lipid scramblase

(2014) Janine D. Brunner et al.   NATURE

Ist2 in the Yeast Cortical Endoplasmic Reticulum Promotes Trafficking of the Amino Acid Transporter Bap2 to the Plasma Membrane

(2014) Wendelin Wolf et al.   PLoS One

Characterization of the Sterol and Phosphatidylinositol 4-Phosphate Binding Properties of Golgi-Associated OSBP-Related Protein 9 (ORP9)

(2014) Xinwei Liu et al.   PLoS One

Structures of PI4KIII  complexes show simultaneous recruitment of Rab11 and its effectors

(2014) J. E. Burke et al.   SCIENCE

Phospholipid Synthesis and Transport in Mammalian Cells

(2014) Jean E. Vance   TRAFFIC

Involvement of Sac1 phosphoinositide phosphatase in the metabolism of phosphatidylserine in the yeastSaccharomyces cerevisiae

(2014) Motohiro Tani et al.   YEAST

Membranous Replication Factories Induced by Plus-Strand RNA Viruses

(2014) Inés Romero-Brey et al.   Viruses-Basel

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

(2014) Radu Stoica et al.   Nature Communications

A Four-Step Cycle Driven by PI(4)P Hydrolysis Directs Sterol/PI(4)P Exchange by the ER-Golgi Tether OSBP

(2013) Bruno Mesmin et al.   CELL

PI(4,5)P2-Dependent and Ca2+-Regulated ER-PM Interactions Mediated by the Extended Synaptotagmins

(2013) Francesca Giordano et al.   CELL

Recruitment of arfaptins to the trans-Golgi network by PI(4)P and their involvement in cargo export

(2013) David Cruz-Garcia et al.   EMBO JOURNAL

The phosphatidylinositol-transfer protein Nir2 binds phosphatidic acid and positively regulates phosphoinositide signalling

(2013) SoHui Kim et al.   EMBO REPORTS

Structural determinants for phosphatidylinositol recognition by Sfh3 and substrate-induced dimer-monomer transition during lipid transfer cycles

(2013) Huiseon Yang et al.   FEBS LETTERS

An Assembly of Proteins and Lipid Domains Regulates Transport of Phosphatidylserine to Phosphatidylserine Decarboxylase 2 inSaccharomyces cerevisiae

(2013) Wayne R. Riekhof et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

cAMP-stimulated phosphorylation of diaphanous 1 regulates protein stability and interaction with binding partners in adrenocortical cells

(2013) Donghui Li et al.   MOLECULAR BIOLOGY OF THE CELL

Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins

(2013) Kenji Maeda et al.   NATURE

Gain-of-function mutations in the phosphatidylserine synthase 1 (PTDSS1) gene cause Lenz-Majewski syndrome

(2013) Sérgio B Sousa et al.   NATURE GENETICS

Impaired  -TTP-PIPs Interaction Underlies Familial Vitamin E Deficiency

(2013) N. Kono et al.   SCIENCE

Structure of Osh3 Reveals a Conserved Mode of Phosphoinositide Binding in Oxysterol-Binding Proteins

(2013) Junsen Tong et al.   STRUCTURE

Feedback Regulation of Receptor-Induced Ca2+ Signaling Mediated by E-Syt1 and Nir2 at Endoplasmic Reticulum-Plasma Membrane Junctions

(2013) Chi-Lun Chang et al.   Cell Reports

ORP10, a cholesterol binding protein associated with microtubules, regulates apolipoprotein B-100 secretion

(2012) Eija Nissilä et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells

(2012) Jean E. Vance et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Roles of SAM and DDHD domains in mammalian intracellular phospholipase A1 KIAA0725p

(2012) Hiroki Inoue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Sterol-Binding Protein Integrates Endosomal Lipid Metabolism with TOR Signaling and Nitrogen Sensing

(2012) Carl J. Mousley et al.   CELL

ER-to-Plasma Membrane Tethering Proteins Regulate Cell Signaling and ER Morphology

(2012) Andrew G. Manford et al.   DEVELOPMENTAL CELL

Sphingomyelin organization is required for vesicle biogenesis at the Golgi complex

(2012) Juan M Duran et al.   EMBO JOURNAL

Phosphatidylinositol Transfer Protein, Cytoplasmic 1 (PITPNC1) Binds and Transfers Phosphatidic Acid

(2012) Kathryn Garner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylinositol 4-Kinase IIα Is Palmitoylated by Golgi-localized Palmitoyltransferases in Cholesterol-dependent Manner

(2012) Dongmei Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multisite phosphorylation of oxysterol-binding protein regulates sterol binding and activation of sphingomyelin synthesis

(2012) Asako Goto et al.   MOLECULAR BIOLOGY OF THE CELL

Yeast Ist2 Recruits the Endoplasmic Reticulum to the Plasma Membrane and Creates a Ribosome-Free Membrane Microcompartment

(2012) Wendelin Wolf et al.   PLoS One

The phosphatidylinositol transfer protein RdgBβ binds 14-3-3 via its unstructured C-terminus, whereas its lipid-binding domain interacts with the integral membrane protein ATRAP (angiotensin II type I receptor-associated protein)

(2011) Kathryn Garner et al.   BIOCHEMICAL JOURNAL

Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites

(2011) Christopher J. Stefan et al.   CELL

A Highly Dynamic ER-Derived Phosphatidylinositol-Synthesizing Organelle Supplies Phosphoinositides to Cellular Membranes

(2011) Yeun Ju Kim et al.   DEVELOPMENTAL CELL

PI4P and Rab Inputs Collaborate in Myosin-V-Dependent Transport of Secretory Compartments in Yeast

(2011) Felipe H. Santiago-Tirado et al.   DEVELOPMENTAL CELL

Phosphatidylserine is a critical modulator for Akt activation

(2011) Bill X. Huang et al.   JOURNAL OF CELL BIOLOGY

A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking

(2011) Ximing Du et al.   JOURNAL OF CELL BIOLOGY

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

(2011) Maud de Saint-Jean et al.   JOURNAL OF CELL BIOLOGY

Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution

(2011) Gabriel Schaaf et al.   MOLECULAR BIOLOGY OF THE CELL

A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells

(2011) Kim J. Png et al.   NATURE

Natural products reveal cancer cell dependence on oxysterol-binding proteins

(2011) Anthony W G Burgett et al.   Nature Chemical Biology

Membrane lipidome of an epithelial cell line

(2011) Julio L. Sampaio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osh Proteins Regulate Membrane Sterol Organization but Are Not Required for Sterol Movement Between the ER and PM

(2011) Alexander G. Georgiev et al.   TRAFFIC

The Sterol-Binding Protein Kes1/Osh4p Is a Regulator of Polarized Exocytosis

(2011) Gabriel Alfaro et al.   TRAFFIC

The Distribution and Function of Phosphatidylserine in Cellular Membranes

(2010) Peter A. Leventis et al.   Annual Review of Biophysics

The Diverse Functions of Oxysterol-Binding Proteins

(2010) Sumana Raychaudhuri et al.   Annual Review of Cell and Developmental Biology

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

Sterol binding by OSBP-related protein 1L regulates late endosome motility and function

(2010) Terhi Vihervaara et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITP  is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum

(2010) N. Carvou et al.   JOURNAL OF CELL SCIENCE

Oxysterol Binding Protein-dependent Activation of Sphingomyelin Synthesis in the Golgi Apparatus Requires Phosphatidylinositol 4-Kinase IIα

(2010) Sangeeta Banerji et al.   MOLECULAR BIOLOGY OF THE CELL

Non-vesicular lipid transport by lipid-transfer proteins and beyond

(2010) Sima Lev   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of ORPs in Sterol Transport from Plasma Membrane to ER and Lipid Droplets in Mammalian Cells

(2010) Maurice Jansen et al.   TRAFFIC

Intracellular sterol dynamics

(2009) Bruno Mesmin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Diacylglycerol kinases as sources of phosphatidic acid

(2009) Jinjin Cai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Phosphatidylethanolamine synthesized by four different pathways is supplied to the plasma membrane of the yeast Saccharomyces cerevisiae

(2009) Irmgard Schuiki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Gluedand late endosome positioning

(2009) Nuno Rocha et al.   JOURNAL OF CELL BIOLOGY

Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network

(2009) Robin W. Klemm et al.   JOURNAL OF CELL BIOLOGY

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

(2009) Timothy A. Schulz et al.   JOURNAL OF CELL BIOLOGY

OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids

(2009) Riikka Hynynen et al.   JOURNAL OF LIPID RESEARCH

Bothnia dystrophy is caused by domino-like rearrangements in cellular retinaldehyde-binding protein mutant R234W

(2009) X. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication

(2009) K. L. Berger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry

(2009) C. S. Ejsing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian phosphoinositide kinases and phosphatases

(2009) Takehiko Sasaki et al.   PROGRESS IN LIPID RESEARCH

Mass spectrometric analysis of lipid species of human circulating blood cells

(2008) Katharina Leidl et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The yeast lysosome-like vacuole: Endpoint and crossroads

(2008) Sheena Claire Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Oxysterol binding protein-related protein-5 is related to invasion and poor prognosis in pancreatic cancer

(2008) Yoshikatsu Koga et al.   CANCER SCIENCE

Mechanisms of Ligand Transfer by the Hepatic Tocopherol Transfer Protein

(2008) Samantha Morley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITP  during axonal extension in hippocampal neurons

(2008) K. E. Cosker et al.   JOURNAL OF CELL SCIENCE

The R-Ras interaction partner ORP3 regulates cell adhesion

(2008) M. Lehto et al.   JOURNAL OF CELL SCIENCE

Determination of the Topology of the Hydrophobic Segment of Mammalian Diacylglycerol Kinase Epsilon in a Cell Membrane and Its Relationship to Predictions from Modeling

(2008) Marc Decaffmeyer et al.   JOURNAL OF MOLECULAR BIOLOGY

Coordinated Lipid Transfer between the Endoplasmic Reticulum and the Golgi Complex Requires the VAP Proteins and Is Essential for Golgi-mediated Transport

(2008) Diego Peretti et al.   MOLECULAR BIOLOGY OF THE CELL

Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14 Superfamily

(2008) Gabriel Schaaf et al.   MOLECULAR CELL

Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

(2008) T. Yeung et al.   SCIENCE

Dynamics of Lipid Transfer by Phosphatidylinositol Transfer Proteins in Cells

(2008) Sadaf Shadan et al.   TRAFFIC