Identification of pathology-specific regulators of m6A RNA modification to optimize lung cancer management in the context of predictive, preventive, and personalized medicine

m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer

(2020) Huilin Huang et al.   CANCER CELL

m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in gastric cancer

(2020) Bo Zhang et al.   Molecular Cancer

VICKZ1 enhances tumor progression and metastasis in lung adenocarcinomas in mice

(2019) Yifat Bar-Zakay Rosenfeld et al.   ONCOGENE

Combining CDK4/6 inhibition with taxanes enhances anti-tumor efficacy by sustained impairment of pRB-E2F pathways in squamous cell lung cancer

(2019) Joan Cao et al.   ONCOGENE

RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3

(2019) Yi Niu et al.   Molecular Cancer

Importance of m N6-methyladenosine (m6A) RNA modification in cancer

(2019) Gulten Tuncel et al.   MEDICAL ONCOLOGY

The m6A demethylase FTO promotes the growth of lung cancer cells by regulating the m6A level of USP7 mRNA

(2019) Jie Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Correlated low IGF2BP1 and FOXM1 expression predicts a good prognosis in lung adenocarcinoma

(2019) Hong Huang et al.   PATHOLOGY RESEARCH AND PRACTICE

KIAA1429 regulates the migration and invasion of hepatocellular carcinoma by altering m6A modification of ID2 mRNA

(2019) Xiaoyu Cheng et al.   OncoTargets and Therapy

Counting the Cuts: MAZTER-Seq Quantifies m6A Levels Using a Methylation-Sensitive Ribonuclease

(2019) Radha Raman Pandey et al.   CELL

Dysregulated N6-methyladenosine methylation writer METTL3 contributes to the proliferation and migration of gastric cancer

(2019) Tong Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner

(2019) Jie Han et al.   Molecular Cancer

METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma

(2019) Ting Li et al.   Molecular Cancer

The regulation, functions and clinical relevance of arginine methylation

(2019) Ernesto Guccione et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

KIAA1429 acts as an oncogenic factor in breast cancer by regulating CDK1 in an N6-methyladenosine-independent manner

(2019) Jia-Yi Qian et al.   ONCOGENE

m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade

(2019) Seungwon Yang et al.   Nature Communications

RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail

(2019) Xinyao Lin et al.   Nature Communications

Signaling pathway network alterations in human ovarian cancers identified with quantitative mitochondrial proteomics

(2019) Na Li et al.   EPMA Journal

Inappropriate modeling of chronic and complex disorders: How to reconsider the approach in the context of predictive, preventive and personalized medicine, and translational medicine

(2019) Soroush Seifirad et al.   EPMA Journal

Exposure to environmental toxicants reduces global N6-methyladenosine RNA methylation and alters expression of RNA methylation modulator genes

(2019) Akin Cayir et al.   ENVIRONMENTAL RESEARCH

Site-specific m6A editing

(2019) Jiangbo Wei et al.   Nature Chemical Biology

AKT-mediated phosphorylation enhances protein stability and transcription activity of ZNF322A to promote lung cancer progression

(2019) Sheng-You Liao et al.   ONCOGENE

Chronic inflammation: key player and biomarker-set to predict and prevent cancer development and progression based on individualized patient profiles

(2019) Shehua Qian et al.   EPMA Journal

Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism

(2018) Ying Yang et al.   CELL RESEARCH

RNA N6-methyladenosine modification in cancers: current status and perspectives

(2018) Xiaolan Deng et al.   CELL RESEARCH

Combination Therapy of Radiotherapy and Anti-PD-1/PD-L1 Treatment in Non–Small-cell Lung Cancer: A Mini-review

(2018) Shinkichi Takamori et al.   Clinical Lung Cancer

Protein tyrosine nitration in lung cancer: current research status and future perspectives

(2018) Xianquan Zhan et al.   CURRENT MEDICINAL CHEMISTRY

The Bayesian adaptive lasso regression

(2018) Rahim Alhamzawi et al.   MATHEMATICAL BIOSCIENCES

Novel insights on m6A RNA methylation in tumorigenesis: a double-edged sword

(2018) Shaoyun Wang et al.   Molecular Cancer

SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function

(2018) Yuzhang Du et al.   NUCLEIC ACIDS RESEARCH

The crucial role of multiomic approach in cancer research and clinically relevant outcomes

(2018) Miaolong Lu et al.   EPMA Journal

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The Krebs Cycle Connection: Reciprocal Influence Between Alternative Splicing Programs and Cell Metabolism

(2018) Giuseppe Biamonti et al.   Frontiers in Oncology

m6A-mediated translation regulation

(2018) Kate D. Meyer   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

It's complicated… m6A-dependent regulation of gene expression in cancer

(2018) Christina M. Fitzsimmons et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

m6A: Widespread regulatory control in virus replication

(2018) Oliver Manners et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The long noncoding RNA LINC00312 induces lung adenocarcinoma migration and vasculogenic mimicry through directly binding YBX1

(2018) Zhenzi Peng et al.   Molecular Cancer

IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner

(2018) Simon Müller et al.   NUCLEIC ACIDS RESEARCH

The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells

(2017) Kosuke Taketo et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Exploration of variations in proteome and metabolome for predictive diagnostics and personalized treatment algorithms: Innovative approach and examples for potential clinical application

(2017) Xianquan Zhan et al.   Journal of Proteomics

Corrigendum: Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex

(2017) Xiang Wang et al.   NATURE

Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance

(2017) A Visvanathan et al.   ONCOGENE

High-throughput m6A-seq reveals RNA m6A methylation patterns in the chloroplast and mitochondria transcriptomes of Arabidopsis thaliana

(2017) Zegang Wang et al.   PLoS One

Pattern recognition for predictive, preventive, and personalized medicine in cancer

(2017) Tingting Cheng et al.   EPMA Journal

Limited resection for early-stage non-small cell lung cancer as function-preserving radical surgery: a review

(2016) Keiju Aokage et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Epidemiology of Lung Cancer

(2016) Yousheng Mao et al.   Surgical Oncology Clinics of North America

Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome

(2015) Bastian Linder et al.   NATURE METHODS

Emerging Roles of RNA Modification: m 6 A and U-Tail

(2014) Mihye Lee et al.   CELL

Bayesian consensus clustering

(2013) Eric F. Lock et al.   BIOINFORMATICS

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

(2010) Matthew D. Wilkerson et al.   BIOINFORMATICS