VICKZ1 enhances tumor progression and metastasis in lung adenocarcinomas in mice

IMP2 and IMP3 cooperate to promote the metastasis of triple-negative breast cancer through destabilization of progesterone receptor

(2018) Hye-Youn Kim et al.   CANCER LETTERS

IGF2BP1 enhances an aggressive tumor cell phenotype by impairing miRNA-directed downregulation of oncogenic factors

(2018) Simon Müller et al.   NUCLEIC ACIDS RESEARCH

Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes

(2018) Sebastian Mueller et al.   NATURE

Dicer loss and recovery induce an oncogenic switch driven by transcriptional activation of the oncofetal Imp1–3 family

(2017) Courtney K. JnBaptiste et al.   GENES & DEVELOPMENT

ETV6/RUNX1 transcript is a target of RNA-binding protein IGF2BP1 in t(12;21)(p13;q22)-positive acute lymphoblastic leukemia

(2016) Mindaugas Stoskus et al.   BLOOD CELLS MOLECULES AND DISEASES

Aspirin inhibits epithelial-to-mesenchymal transition and migration of oncogenic K-ras-expressing non-small cell lung carcinoma cells by down-regulating E-cadherin repressor Slug

(2016) Poulami Khan et al.   BMC CANCER

SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b

(2016) Sita Kugel et al.   CELL

IMPs: an RNA-binding protein family that provides a link between stem cell maintenance in normal development and cancer

(2016) Nils Degrauwe et al.   GENES & DEVELOPMENT

The oncogenic triangle of HMGA2, LIN28B and IGF2BP1 antagonizes tumor-suppressive actions of the let-7 family

(2016) Bianca Busch et al.   NUCLEIC ACIDS RESEARCH

IMP1, an mRNA binding protein that reduces the metastatic potential of breast cancer in a mouse model

(2016) Chiso U. Nwokafor et al.   Oncotarget

Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma

(2016) Ahmad Barghash et al.   Oncotarget

The RNA Binding Protein IMP2 Preserves Glioblastoma Stem Cells by Preventing let-7 Target Gene Silencing

(2016) Nils Degrauwe et al.   Cell Reports

Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival

(2016) Anne E. Conway et al.   Cell Reports

IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins

(2015) Ning Dai et al.   Cell Metabolism

Localization of cofilin mRNA to the leading edge of migrating cells promotes directed cell migration

(2015) Y. Maizels et al.   JOURNAL OF CELL SCIENCE

Clinical implications of insulin-like growth factor II mRNA-binding protein 3 expression in non-small cell lung carcinoma

(2015) JINHUI ZHANG et al.   Oncology Letters

A Novel Role for VICKZ Proteins in Maintaining Epithelial Integrity during Embryogenesis

(2015) Michal Shoshkes Carmel et al.   PLoS One

Oncofetal Protein IMP3, a New Cancer Biomarker

(2014) Yuna Gong et al.   ADVANCES IN ANATOMIC PATHOLOGY

The clinical relevance of KRAS gene mutation in non-small-cell lung cancer

(2014) József Tímár   CURRENT OPINION IN ONCOLOGY

VICKZ2 protein expression in ovarian serous carcinoma effusions is associated with poor survival

(2014) Ben Davidson et al.   HUMAN PATHOLOGY

TheIGF2mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis

(2014) Stephan Laggai et al.   JOURNAL OF LIPID RESEARCH

Oncogenic Ras/ERK Signaling Activates CDCP1 to Promote Tumor Invasion and Metastasis

(2014) Takamasa Uekita et al.   MOLECULAR CANCER RESEARCH

IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts

(2013) Kathryn E. Hamilton et al.   CARCINOGENESIS

RNA-binding protein Vg1RBP regulates terminal arbor formation but not long-range axon navigation in the developing visual system

(2013) Adrianna Kalous et al.   Developmental Neurobiology

mTOR complex 2 phosphorylates IMP1 cotranslationally to promote IGF2 production and the proliferation of mouse embryonic fibroblasts

(2013) N. Dai et al.   GENES & DEVELOPMENT

IMP3 Protein Promotes Chemoresistance in Breast Cancer Cells by Regulating Breast Cancer Resistance Protein (ABCG2) Expression

(2013) Sanjoy Samanta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells

(2013) Chia-Lin Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?

(2012) Jessica L. Bell et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling

(2012) N. Stohr et al.   GENES & DEVELOPMENT

Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells

(2012) M. Janiszewska et al.   GENES & DEVELOPMENT

Regulation of local expression of cell adhesion and motility-related mRNAs in breast cancer cells by IMP1/ZBP1

(2012) W. Gu et al.   JOURNAL OF CELL SCIENCE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

IMP-1 Displays Cross-Talk with K-Ras and Modulates Colon Cancer Cell Survival through the Novel Proapoptotic Protein CYFIP2

(2011) P. S. Mongroo et al.   CANCER RESEARCH

mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry

(2011) N. Dai et al.   GENES & DEVELOPMENT

Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1

(2011) Benjamin Boyerinas et al.   INTERNATIONAL JOURNAL OF CANCER

Monocyte Chemoattractant Protein–1 Blockade Inhibits Lung Cancer Tumor Growth by Altering Macrophage Phenotype and Activating CD8+Cells

(2010) Zvi G. Fridlender et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

MicroRNA-340-mediated Degradation of Microphthalmia-associated Transcription Factor mRNA Is Inhibited by the Coding Region Determinant-binding Protein

(2010) Srikanta Goswami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wnt Signaling Stimulates Transcriptional Outcome of the Hedgehog Pathway by Stabilizing GLI1 mRNA

(2009) F. K. Noubissi et al.   CANCER RESEARCH

Blocking  -catenin binding to the ZBP1 promoter represses ZBP1 expression, leading to increased proliferation and migration of metastatic breast-cancer cells

(2009) W. Gu et al.   JOURNAL OF CELL SCIENCE

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

(2009) Michel DuPage et al.   Nature Protocols

A role for VICKZ proteins in the progression of colorectal carcinomas: regulating lamellipodia formation

(2008) G Vainer et al.   JOURNAL OF PATHOLOGY