Signals Orchestrating Peripheral Nerve Repair

DNA methylation in Schwann cells and in oligodendrocytes

(2020) Peter Arthur‐Farraj et al.   GLIA

Functions of histone modifications and histone modifiers in Schwann cells

(2020) Mert Duman et al.   GLIA

Axon-dependent expression of YAP/TAZ mediates Schwann cell remyelination but not proliferation after nerve injury

(2020) Matthew Grove et al.   eLife

Repair Schwann cell update: Adaptive reprogramming, EMT, and stemness in regenerating nerves

(2019) Kristjan R Jessen et al.   GLIA

Macrophage-Derived Slit3 Controls Cell Migration and Axon Pathfinding in the Peripheral Nerve Bridge

(2019) Xin-peng Dun et al.   Cell Reports

The Success and Failure of the Schwann Cell Response to Nerve Injury

(2019) Kristjan R. Jessen et al.   Frontiers in Cellular Neuroscience

Paracrine Mechanisms of Redox Signalling for Postmitotic Cell and Tissue Regeneration

(2019) Arnau Hervera et al.   TRENDS IN CELL BIOLOGY

The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration

(2019) Yuanquan Song et al.   NEURON

PP4‐dependent HDAC3 dephosphorylation discriminates between axonal regeneration and regenerative failure

(2019) Arnau Hervera et al.   EMBO JOURNAL

Beyond Trophic Factors: Exploiting the Intrinsic Regenerative Properties of Adult Neurons

(2019) Arul Duraikannu et al.   Frontiers in Cellular Neuroscience

Schwann cell plasticity-roles in tissue homeostasis, regeneration, and disease

(2019) Salome Stierli et al.   GLIA

Specialized cutaneous Schwann cells initiate pain sensation

(2019) Hind Abdo et al.   SCIENCE

An Agonist of the CXCR4 Receptor Strongly Promotes Regeneration of Degenerated Motor Axon Terminals

(2019) Negro et al.   Cells

Epigenomic signatures underpin the axonal regenerative ability of dorsal root ganglia sensory neurons

(2019) Ilaria Palmisano et al.   NATURE NEUROSCIENCE

A CXCR4 receptor agonist strongly stimulates axonal regeneration after damage

(2019) Giulia Zanetti et al.   Annals of Clinical and Translational Neurology

Neuromuscular Junction Formation, Aging, and Disorders

(2018) Lei Li et al.   Annual Review of Physiology

Axonal mRNA transport and translation at a glance

(2018) Pabitra K. Sahoo et al.   JOURNAL OF CELL SCIENCE

Publisher Correction: Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

(2018) Arnau Hervera et al.   NATURE CELL BIOLOGY

Advances and Limitations of Current Epigenetic Studies Investigating Mammalian Axonal Regeneration

(2018) Ilaria Palmisano et al.   Neurotherapeutics

The intriguing nature of dorsal root ganglion neurons: linking structure with polarity and function

(2018) Ana Isabel Nascimento et al.   PROGRESS IN NEUROBIOLOGY

Hydrogen peroxide is a neuronal alarmin that triggers specific RNAs, local translation of Annexin A2, and cytoskeletal remodeling in Schwann cells

(2018) Samuele Negro et al.   RNA

Locally translated mTOR controls axonal local translation in nerve injury

(2018) Marco Terenzio et al.   SCIENCE

Axon Regeneration in the Central Nervous System: Facing the Challenges from the Inside

(2018) Michele Curcio et al.   Annual Review of Cell and Developmental Biology

Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells

(2018) Maria Montserrat Garcia Romero et al.   Nature Communications

A Regeneration Toolkit

(2018) Mayssa H. Mokalled et al.   DEVELOPMENTAL CELL

Learning to swim, again: Axon regeneration in fish

(2017) Jeffrey P. Rasmussen et al.   EXPERIMENTAL NEUROLOGY

The Glia Response after Peripheral Nerve Injury: A Comparison between Schwann Cells and Olfactory Ensheathing Cells and Their Uses for Neural Regenerative Therapies

(2017) Matthew Barton et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Netrin-1 Signaling in Nerve Regeneration

(2017) Xin-Peng Dun et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Animal models for studying motor axon terminal paralysis and recovery

(2017) Michela Rigoni et al.   JOURNAL OF NEUROCHEMISTRY

After Nerve Injury, Lineage Tracing Shows That Myelin and Remak Schwann Cells Elongate Extensively and Branch to Form Repair Schwann Cells, Which Shorten Radically on Remyelination

(2017) Jose A. Gomez-Sanchez et al.   JOURNAL OF NEUROSCIENCE

Epigenetic Regulation of Axon Regeneration after Neural Injury

(2017) Jung Eun Shin et al.   MOLECULES AND CELLS

Floor-plate-derived netrin-1 is dispensable for commissural axon guidance

(2017) Chloé Dominici et al.   NATURE

The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration

(2017) Melanie P. Clements et al.   NEURON

Compartmentalized Signaling in Neurons: From Cell Biology to Neuroscience

(2017) Marco Terenzio et al.   NEURON

Influence of Mechanical Stimuli on Schwann Cell Biology

(2017) Sophie Belin et al.   Frontiers in Cellular Neuroscience

A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination

(2017) Yaqi Deng et al.   Nature Communications

Changes in the Coding and Non-coding Transcriptome and DNA Methylome that Define the Schwann Cell Repair Phenotype after Nerve Injury

(2017) Peter J. Arthur-Farraj et al.   Cell Reports

YAP/TAZ initiate and maintain Schwann cell myelination

(2017) Matthew Grove et al.   eLife

Nerves Control Redox Levels in Mature Tissues Through Schwann Cells and Hedgehog Signaling

(2016) Francesca Meda et al.   ANTIOXIDANTS & REDOX SIGNALING

The multicellular complexity of peripheral nerve regeneration

(2016) Anne-Laure Cattin et al.   CURRENT OPINION IN NEUROBIOLOGY

Hydrogen peroxide (H 2 O 2 ) controls axon pathfinding during zebrafish development

(2016) Carole Gauron et al.   DEVELOPMENTAL BIOLOGY

YAP functions as a mechanotransducer in oligodendrocyte morphogenesis and maturation

(2016) Takeshi Shimizu et al.   GLIA

Axonal degeneration, distal collateral branching and neuromuscular junction architecture alterations occur prior to symptom onset in the SOD1G93A mouse model of amyotrophic lateral sclerosis

(2016) Jayden A. Clark et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Gpr126/Adgrg6 Has Schwann Cell Autonomous and Nonautonomous Functions in Peripheral Nerve Injury and Repair

(2016) Amit Mogha et al.   JOURNAL OF NEUROSCIENCE

Nerve regeneration in the peripheral and central nervous systems

(2016) Tessa Gordon   JOURNAL OF PHYSIOLOGY-LONDON

The repair Schwann cell and its function in regenerating nerves

(2016) K. R. Jessen et al.   JOURNAL OF PHYSIOLOGY-LONDON

YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells

(2016) Yannick Poitelon et al.   NATURE NEUROSCIENCE

Epigenomic reprogramming in peripheral nerve injury

(2016) John Svaren et al.   Neural Regeneration Research

An animal model of Miller Fisher syndrome: Mitochondrial hydrogen peroxide is produced by the autoimmune attack of nerve terminals and activates Schwann cells

(2016) Umberto Rodella et al.   NEUROBIOLOGY OF DISEASE

The Calcium Channel Subunit Alpha2delta2 Suppresses Axon Regeneration in the Adult CNS

(2016) Andrea Tedeschi et al.   NEURON

Intrinsic Control of Axon Regeneration

(2016) Zhigang He et al.   NEURON

ATP Released by Injured Neurons Activates Schwann Cells

(2016) Samuele Negro et al.   Frontiers in Cellular Neuroscience

Non-coding RNAs as Emerging Regulators of Neural Injury Responses and Regeneration

(2016) Songlin Zhou et al.   Neuroscience Bulletin

Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves

(2015) Anne-Laure Cattin et al.   CELL

Fibroblast-derived tenascin-C promotes Schwann cell migration through β1-integrin dependent pathway during peripheral nerve regeneration

(2015) Zhanhu Zhang et al.   GLIA

Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves

(2015) Jose A. Gomez-Sanchez et al.   JOURNAL OF CELL BIOLOGY

Signaling Over Distances

(2015) Atsushi Saito et al.   MOLECULAR & CELLULAR PROTEOMICS

Molecular and Cellular Mechanisms of Axonal Regeneration After Spinal Cord Injury

(2015) Erna A. van Niekerk et al.   MOLECULAR & CELLULAR PROTEOMICS

Mitochondrial alarmins released by degenerating motor axon terminals activate perisynaptic Schwann cells

(2015) Elisa Duregotti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of cytoskeletal dynamics by redox signaling and oxidative stress: implications for neuronal development and trafficking

(2015) Carlos Wilson et al.   Frontiers in Cellular Neuroscience

Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination

(2015) Y. Poitelon et al.   Nature Communications

HDAC signaling in neuronal development and axon regeneration

(2014) Yongcheol Cho et al.   CURRENT OPINION IN NEUROBIOLOGY

Chemokine signaling in development and disease

(2014) J. Wang et al.   DEVELOPMENT

C. elegans Epidermal Wounding Induces a Mitochondrial ROS Burst that Promotes Wound Repair

(2014) Suhong Xu et al.   DEVELOPMENTAL CELL

Contrasting the Glial Response to Axon Injury in the Central and Peripheral Nervous Systems

(2014) Amanda Brosius Lutz et al.   DEVELOPMENTAL CELL

CXC chemokine ligand 12 (CXCL12) and its receptor CXCR4

(2014) Takashi Nagasawa   JOURNAL OF MOLECULAR MEDICINE-JMM

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neuromuscular synaptogenesis: coordinating partners with multiple functions

(2014) Houssam Darabid et al.   NATURE REVIEWS NEUROSCIENCE

Wallerian degeneration: an emerging axon death pathway linking injury and disease

(2014) Laura Conforti et al.   NATURE REVIEWS NEUROSCIENCE

CXCL12 chemokine and its receptors as major players in the interactions between immune and nervous systems

(2014) Alice Guyon   Frontiers in Cellular Neuroscience

PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system

(2014) Radhika Puttagunta et al.   Nature Communications

Degeneration of Neuromuscular Junction in Age and Dystrophy

(2014) Rüdiger Rudolf et al.   Frontiers in Aging Neuroscience

ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease

(2014) Elizabeth B. Moloney et al.   Frontiers in Neuroscience

Injury-Induced HDAC5 Nuclear Export Is Essential for Axon Regeneration

(2013) Yongcheol Cho et al.   CELL

At the “Junction” of Spinal Muscular Atrophy Pathogenesis: The Role of Neuromuscular Junction Dysfunction in SMA Disease Progression

(2013) B. Goulet et al.   CURRENT MOLECULAR MEDICINE

Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration

(2013) Nick R. Love et al.   NATURE CELL BIOLOGY

Axon–soma communication in neuronal injury

(2013) Ida Rishal et al.   NATURE REVIEWS NEUROSCIENCE

Characterization of early pathogenesis in the SOD1G93Amouse model of ALS: part II, results and discussion

(2013) Sharon Vinsant et al.   Brain and Behavior

HDAC5 is a novel injury-regulated tubulin deacetylase controlling axon regeneration

(2012) Yongcheol Cho et al.   EMBO JOURNAL

Live Imaging Reveals Differing Roles of Macrophages and Neutrophils during Zebrafish Tail Fin Regeneration

(2012) Li Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish

(2012) Sa Kan Yoo et al.   JOURNAL OF CELL BIOLOGY

c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling

(2012) Xavier Fontana et al.   JOURNAL OF CELL BIOLOGY

The challenges and beauty of peripheral nerve regrowth

(2012) Douglas W. Zochodne   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Assembly of a new growth cone after axotomy: the precursor to axon regeneration

(2012) Frank Bradke et al.   NATURE REVIEWS NEUROSCIENCE

A Central Role for the ERK-Signaling Pathway in Controlling Schwann Cell Plasticity and Peripheral Nerve Regeneration In Vivo

(2012) Ilaria Napoli et al.   NEURON

c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration

(2012) Peter J. Arthur-Farraj et al.   NEURON

Dual Leucine Zipper Kinase Is Required for Retrograde Injury Signaling and Axonal Regeneration

(2012) Jung Eun Shin et al.   NEURON

Tuning the Orchestra: Transcriptional Pathways Controlling Axon Regeneration

(2012) Andrea Tedeschi   Frontiers in Molecular Neuroscience

Neuronal Intrinsic Mechanisms of Axon Regeneration

(2011) Kai Liu et al.   Annual Review of Neuroscience

Wallerian degeneration: the innate-immune response to traumatic nerve injury

(2011) Shlomo Rotshenker   Journal of Neuroinflammation

Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury

(2011) F. Hellal et al.   SCIENCE

Hydrogen peroxide: a Jekyll and Hyde signalling molecule

(2011) D R Gough et al.   Cell Death & Disease

Hydrogen Peroxide Promotes Injury-Induced Peripheral Sensory Axon Regeneration in the Zebrafish Skin

(2011) Sandra Rieger et al.   PLOS BIOLOGY

EphB Signaling Directs Peripheral Nerve Regeneration through Sox2-Dependent Schwann Cell Sorting

(2010) Simona Parrinello et al.   CELL

Inactivation of Peroxiredoxin I by Phosphorylation Allows Localized H2O2 Accumulation for Cell Signaling

(2010) Hyun Ae Woo et al.   CELL

Electrical Activity Suppresses Axon Growth through Cav1.2 Channels in Adult Primary Sensory Neurons

(2010) Joana Enes et al.   CURRENT BIOLOGY

Influence of aging on peripheral nerve function and regeneration

(2010) Enrique Verdú et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling

(2010) E. W. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial-targeted fluorescent probes for reactive oxygen species

(2009) Bryan C Dickinson et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

SDF1/CXCR4 signalling regulates two distinct processes of precerebellar neuronal migration and its depletion leads to abnormal pontine nuclei formation

(2009) Y. Zhu et al.   DEVELOPMENT

A conditioning lesion induces changes in gene expression and axonal transport that enhance regeneration by increasing the intrinsic growth state of axons

(2009) Paul N. Hoffman   EXPERIMENTAL NEUROLOGY

Dynamics of axonal mRNA transport and implications for peripheral nerve regeneration

(2009) Soonmoon Yoo et al.   EXPERIMENTAL NEUROLOGY

Locally Synthesized Calcitonin Gene-Related Peptide Has a Critical Role in Peripheral Nerve Regeneration

(2009) Cory C. Toth et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Pathophysiological actions of neuropathy-related anti-ganglioside antibodies at the neuromuscular junction

(2009) Jaap J. Plomp et al.   JOURNAL OF PHYSIOLOGY-LONDON

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

HDAC6 is a target for protection and regeneration following injury in the nervous system

(2009) M. A. Rivieccio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium overload in nerve terminals of cultured neurons intoxicated by alpha-latrotoxin and snake PLA2 neurotoxins

(2009) Erik Tedesco et al.   TOXICON

Interactions between Schwann cells and macrophages in injury and inherited demyelinating disease

(2008) Rudolf Martini et al.   GLIA

Schwann Cell to Axon Transfer of Ribosomes: Toward a Novel Understanding of the Role of Glia in the Nervous System

(2008) F. A. Court et al.   JOURNAL OF NEUROSCIENCE