Signaling Over Distances

Cellular Functions of the Amyloid Precursor Protein from Development to Dementia

(2015) Rik van der Kant et al.   DEVELOPMENTAL CELL

Pharmacologically inhibiting kinesin-5 activity with monastrol promotes axonal regeneration following spinal cord injury

(2015) Chen Xu et al.   EXPERIMENTAL NEUROLOGY

Tubulin-tyrosine Ligase (TTL)-mediated Increase in Tyrosinated α-Tubulin in Injured Axons Is Required for Retrograde Injury Signaling and Axon Regeneration

(2015) Wenjun Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

JIP3 Activates Kinesin-1 Motility to Promote Axon Elongation

(2015) Dana Watt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Axonal Amphoterin mRNA Is Regulated by Translational Control and Enhances Axon Outgrowth

(2015) T. T. Merianda et al.   JOURNAL OF NEUROSCIENCE

Growth Cone Localization of the mRNA Encoding the Chromatin Regulator HMGN5 Modulates Neurite Outgrowth

(2015) Francesca Moretti et al.   MOLECULAR AND CELLULAR BIOLOGY

Effects of kinesin-5 inhibition on dendritic architecture and microtubule organization

(2015) Olga I. Kahn et al.   MOLECULAR BIOLOGY OF THE CELL

Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury

(2015) Vera Valakh et al.   NEUROBIOLOGY OF DISEASE

Injury-Induced Decline of Intrinsic Regenerative Ability Revealed by Quantitative Proteomics

(2015) Stephane Belin et al.   NEURON

Systemic administration of epothilone B promotes axon regeneration after spinal cord injury

(2015) J. Ruschel et al.   SCIENCE

Macromolecular transport in synapse to nucleus communication

(2015) Nicolas Panayotis et al.   TRENDS IN NEUROSCIENCES

MAPK8IP1/JIP1 regulates the trafficking of autophagosomes in neurons

(2014) Meng-meng Fu et al.   Autophagy

Axonally Synthesized ATF4 Transmits a Neurodegenerative Signal across Brain Regions

(2014) Jimena Baleriola et al.   CELL

Remote Control of Gene Function by Local Translation

(2014) Hosung Jung et al.   CELL

LC3 Binding to the Scaffolding Protein JIP1 Regulates Processive Dynein-Driven Transport of Autophagosomes

(2014) Meng-meng Fu et al.   DEVELOPMENTAL CELL

Autophagosome Biogenesis in Primary Neurons Follows an Ordered and Spatially Regulated Pathway

(2014) Sandra Maday et al.   DEVELOPMENTAL CELL

Rabies Virus Envelope Glycoprotein Targets Lentiviral Vectors to the Axonal Retrograde Pathway in Motor Neurons

(2014) James N. Hislop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

(2014) Ghazaleh Ashrafi et al.   JOURNAL OF CELL BIOLOGY

Calcium Release from Intra-Axonal Endoplasmic Reticulum Leads to Axon Degeneration through Mitochondrial Dysfunction

(2014) R. Villegas et al.   JOURNAL OF NEUROSCIENCE

Neuronal Regeneration in C. elegans Requires Subcellular Calcium Release by Ryanodine Receptor Channels and Can Be Enhanced by Optogenetic Stimulation

(2014) L. Sun et al.   JOURNAL OF NEUROSCIENCE

Histone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury

(2014) Heather M Schmitt et al.   Molecular Neurodegeneration

Local Translation and Retrograde Axonal Transport of CREB Regulates IL-6-Induced Nociceptive Plasticity

(2014) Ohannes K Melemedjian et al.   Molecular Pain

Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation

(2014) Sandra Maday et al.   NEURON

Sensing nerve injury at the axonal ER: Activated Luman/CREB3 serves as a novel axonally synthesized retrograde regeneration signal

(2014) Zhengxin Ying et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nidogens are therapeutic targets for the prevention of tetanus

(2014) K. Bercsenyi et al.   SCIENCE

Histone deacetylases in memory and cognition

(2014) J. Penney et al.   Science Signaling

Neuronal Signaling through Endocytosis

(2014) K. E. Cosker et al.   Cold Spring Harbor Perspectives in Biology

PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system

(2014) Radhika Puttagunta et al.   Nature Communications

Bicaudal D Family Adaptor Proteins Control the Velocity of Dynein-Based Movements

(2014) Max A. Schlager et al.   Cell Reports

Rabies Virus Hijacks and Accelerates the p75NTR Retrograde Axonal Transport Machinery

(2014) Shani Gluska et al.   PLoS Pathogens

Injury-Induced HDAC5 Nuclear Export Is Essential for Axon Regeneration

(2013) Yongcheol Cho et al.   CELL

Axonal transcription factors: Novel regulators of growth cone-to-nucleus signaling

(2013) Sheng-Jian Ji et al.   Developmental Neurobiology

c-Jun NH2-terminal Kinase (JNK)-interacting Protein-3 (JIP3) Regulates Neuronal Axon Elongation in a Kinesin- and JNK-dependent Manner

(2013) Tao Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors

(2013) Meng-meng Fu et al.   JOURNAL OF CELL BIOLOGY

JNK-mediated phosphorylation of DLK suppresses its ubiquitination to promote neuronal apoptosis

(2013) Sarah Huntwork-Rodriguez et al.   JOURNAL OF CELL BIOLOGY

Time-resolved quantitative proteomics implicates the core snRNP protein SmB together with SMN in neural trafficking

(2013) Alan R. Prescott et al.   JOURNAL OF CELL SCIENCE

Axon–soma communication in neuronal injury

(2013) Ida Rishal et al.   NATURE REVIEWS NEUROSCIENCE

Axonal transport deficits and neurodegenerative diseases

(2013) Stéphanie Millecamps et al.   NATURE REVIEWS NEUROSCIENCE

Transcription Factor SCIRR69 Involved in the Activation of Brain-Derived Neurotrophic Factor Gene Promoter II in Mechanically Injured Neurons

(2013) Yong Liu et al.   NEUROMOLECULAR MEDICINE

Signalling endosomes in axonal transport: Travel updates on the molecular highway

(2013) Nathalie Schmieg et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Proteomic characterization of novel histone post-translational modifications

(2013) Anna M Arnaudo et al.   Epigenetics & Chromatin

JNK-Interacting Protein 3 Mediates the Retrograde Transport of Activated c-Jun N-Terminal Kinase and Lysosomes

(2013) Catherine M. Drerup et al.   PLoS Genetics

Asymmetrically Modified Nucleosomes

(2012) Philipp Voigt et al.   CELL

HDAC5 is a novel injury-regulated tubulin deacetylase controlling axon regeneration

(2012) Yongcheol Cho et al.   EMBO JOURNAL

Axonal transcription factors signal retrogradely in lesioned peripheral nerve

(2012) Keren Ben-Yaakov et al.   EMBO JOURNAL

PUB-NChIP--"in vivo biotinylation" approach to study chromatin in proximity to a protein of interest

(2012) M. Shoaib et al.   GENOME RESEARCH

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

(2012) Sandra Maday et al.   JOURNAL OF CELL BIOLOGY

Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair

(2012) Hosung Jung et al.   NATURE REVIEWS NEUROSCIENCE

Assembly of a new growth cone after axotomy: the precursor to axon regeneration

(2012) Frank Bradke et al.   NATURE REVIEWS NEUROSCIENCE

Regulation of DLK-1 Kinase Activity by Calcium-Mediated Dissociation from an Inhibitory Isoform

(2012) Dong Yan et al.   NEURON

Dual Leucine Zipper Kinase Is Required for Retrograde Injury Signaling and Axonal Regeneration

(2012) Jung Eun Shin et al.   NEURON

Axonal transport and neurodegenerative disease: Can we see the elephant?

(2012) Lawrence S.B. Goldstein   PROGRESS IN NEUROBIOLOGY

Epigenetic modifications of the neuroproteome

(2012) Andrea M. Brunner et al.   PROTEOMICS

mRNA Localization: An Orchestration of Assembly, Traffic and Synthesis

(2012) Lei Xing et al.   TRAFFIC

Mitochondria as a central sensor for axonal degenerative stimuli

(2012) Felipe A. Court et al.   TRENDS IN NEUROSCIENCES

A Motor-Driven Mechanism for Cell-Length Sensing

(2012) Ida Rishal et al.   Cell Reports

Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins

(2012) Gary LeRoy et al.   GENOME BIOLOGY

Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility

(2011) Faneng Sun et al.   EMBO JOURNAL

JIP3 Mediates TrkB Axonal Anterograde Transport and Enhances BDNF Signaling by Directly Bridging TrkB with Kinesin-1

(2011) S.-H. Huang et al.   JOURNAL OF NEUROSCIENCE

Taxol Facilitates Axon Regeneration in the Mature CNS

(2011) V. Sengottuvel et al.   JOURNAL OF NEUROSCIENCE

The Caenorhabditis elegans JIP3 Protein UNC-16 Functions As an Adaptor to Link Kinesin-1 with Cytoplasmic Dynein

(2011) M. Arimoto et al.   JOURNAL OF NEUROSCIENCE

Neuronal protein trafficking: Emerging consequences of endoplasmic reticulum dynamics

(2011) José Ignacio Valenzuela et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury

(2011) F. Hellal et al.   SCIENCE

Axotomy induces axonogenesis in hippocampal neurons through STAT3

(2011) R Ohara et al.   Cell Death & Disease

Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis

(2010) Heather R. Pelzel et al.   BMC NEUROSCIENCE

Emerging themes of ER organization in the development and maintenance of axons

(2010) Benoît Renvoisé et al.   CURRENT OPINION IN NEUROBIOLOGY

Going global: Novel histone modifications in the globular domain of H3

(2010) Philipp Tropberger et al.   Epigenetics

Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury

(2010) Xin Xiong et al.   JOURNAL OF CELL BIOLOGY

Calcium and Cyclic AMP Promote Axonal Regeneration in Caenorhabditis elegans and Require DLK-1 Kinase

(2010) A. Ghosh-Roy et al.   JOURNAL OF NEUROSCIENCE

Subcellular Communication Through RNA Transport and Localized Protein Synthesis

(2010) Christopher J. Donnelly et al.   TRAFFIC

Retrograde axonal transport: pathways to cell death?

(2010) Eran Perlson et al.   TRENDS IN NEUROSCIENCES

Local calcium-dependent mechanisms determine whether a cut axonal end assembles a retarded endbulb or competent growth cone

(2009) Dotan Kamber et al.   EXPERIMENTAL NEUROLOGY

The role of local protein synthesis and degradation in axon regeneration

(2009) Laura F. Gumy et al.   EXPERIMENTAL NEUROLOGY

Dynamics of axonal mRNA transport and implications for peripheral nerve regeneration

(2009) Soonmoon Yoo et al.   EXPERIMENTAL NEUROLOGY

Sunday Driver Interacts with Two Distinct Classes of Axonal Organelles

(2009) Namiko Abe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ran on tracks - cytoplasmic roles for a nuclear regulator

(2009) D. Yudin et al.   JOURNAL OF CELL SCIENCE

Calpain Mediates Proteolysis of the Voltage-Gated Sodium Channel  -Subunit

(2009) C. R. von Reyn et al.   JOURNAL OF NEUROSCIENCE

HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage

(2009) Jin Young Kim et al.   NATURE NEUROSCIENCE

HDAC6 is a target for protection and regeneration following injury in the nervous system

(2009) M. A. Rivieccio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Axon Regeneration Requires a Conserved MAP Kinase Pathway

(2009) M. Hammarlund et al.   SCIENCE

Nuclear transport factors in neuronal function

(2009) Rotem Ben-Tov Perry et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Role of Axonal Transport in Neurodegenerative Diseases

(2008) Kurt J. De Vos et al.   Annual Review of Neuroscience

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

(2008) Emilie Colin et al.   EMBO JOURNAL

Histone deacetylase 3 localizes to the mitotic spindle and is required for kinetochore-microtubule attachment

(2008) S. Ishii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA