Design and Testing of a Custom Melanoma Next Generation Sequencing Panel for Analysis of Circulating Tumor DNA

TERT, BRAF, and NRAS mutational heterogeneity between paired primary and metastatic melanoma tumors

(2020) Gregory A. Chang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Pre‐analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients

(2020) Svenja Schneegans et al.   Molecular Oncology

Monitoring melanoma recurrence with circulating tumor DNA: a proof of concept from three case studies

(2019) Ashleigh C. McEvoy et al.   Oncotarget

Genomic Analysis of Circulating Tumor DNA Using a Melanoma-Specific UltraSEEK Oncogene Panel

(2019) Elin S. Gray et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Prediction and monitoring of relapse in stage III melanoma using circulating tumor DNA

(2019) L Tan et al.   ANNALS OF ONCOLOGY

Pre-operative ctDNA predicts survival in high-risk stage III cutaneous melanoma patients

(2019) J H Lee et al.   ANNALS OF ONCOLOGY

The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma

(2019) Bengt Phung et al.   Cell Reports

Undetectable circulating tumor DNA (ctDNA) levels correlate with favorable outcome in metastatic melanoma patients treated with anti-PD1 therapy

(2019) Teofila Seremet et al.   Journal of Translational Medicine

Technical progress in circulating tumor DNA analysis using next generation sequencing

(2019) Yunfei Bai et al.   MOLECULAR AND CELLULAR PROBES

Blood‐Based Next‐Generation Sequencing Analysis of Appendiceal Cancers

(2019) Walid L. Shaib et al.   ONCOLOGIST

Intra-Patient Heterogeneity of Circulating Tumor Cells and Circulating Tumor DNA in Blood of Melanoma Patients

(2019) Katharina Gorges et al.   Cancers

Analysis of the Whole-Exome Sequencing of Tumor and Circulating Tumor DNA in Metastatic Melanoma

(2019) Russell J. Diefenbach et al.   Cancers

Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway

(2019) Sisi Chen et al.   Nature Communications

Circulating Tumor DNA: Measurement and Clinical Utility

(2018) Joshua Donaldson et al.   Annual Review of Medicine

Correlation between circulating tumour DNA and metabolic tumour burden in metastatic melanoma patients

(2018) Ashleigh C. McEvoy et al.   BMC CANCER

Comprehensive Characterization of Cancer Driver Genes and Mutations

(2018) Matthew H. Bailey et al.   CELL

Optimizing Amplification of the GC-RichTERTPromoter Region Using 7-Deaza-dGTP for Droplet Digital PCR Quantification ofTERTPromoter Mutations

(2018) Andrew J. Colebatch et al.   CLINICAL CHEMISTRY

Plasma total cell-free DNA (cfDNA) is a surrogate biomarker for tumour burden and a prognostic biomarker for survival in metastatic melanoma patients

(2018) S. Valpione et al.   EUROPEAN JOURNAL OF CANCER

Untargeted profiling of cell-free circulating DNA

(2018) Qing Zhou et al.   Translational Cancer Research

Association Between Circulating Tumor DNA and Pseudoprogression in Patients With Metastatic Melanoma Treated With Anti–Programmed Cell Death 1 Antibodies

(2018) Jenny H. Lee et al.   JAMA Oncology

Circulating tumor DNA – Current state of play and future perspectives

(2018) Gabriele De Rubis et al.   PHARMACOLOGICAL RESEARCH

Monitoring Melanoma Using Circulating Free DNA

(2018) Russell J. Diefenbach et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

Detection of mutations in SF3B1, EIF1AX and GNAQ in primary orbital melanoma by candidate gene analysis

(2018) Anna M. Rose et al.   BMC CANCER

Development of Novel Mutation-Specific Droplet Digital PCR Assays Detecting TERT Promoter Mutations in Tumor and Plasma Samples

(2018) Broderick Corless et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Locus-specific concordance of genomic alterations between tissue and plasma circulating tumor DNA in metastatic melanoma

(2018) Leslie Calapre et al.   Molecular Oncology

The feasibility of using mutation detection in ctDNA to assess tumor dynamics

(2017) Xin Yi et al.   INTERNATIONAL JOURNAL OF CANCER

Whole-genome landscapes of major melanoma subtypes

(2017) Nicholas K. Hayward et al.   NATURE

Sensitive droplet digital PCR method for detection of TERT promoter mutations in cell free DNA from patients with metastatic melanoma

(2017) Ashleigh C. McEvoy et al.   Oncotarget

BRAFV600EandNRASQ61L/Q61Rmutation analysis in metastatic melanoma using immunohistochemistry: a study of 754 cases highlighting potential pitfalls and guidelines for interpretation and reporting

(2016) Hojabr Kakavand et al.   HISTOPATHOLOGY

TERTpromoter mutations in melanoma survival

(2016) Eduardo Nagore et al.   INTERNATIONAL JOURNAL OF CANCER

EGFR and KRAS mutational analysis in a large series of Italian non-small cell lung cancer patients: 2,387 cases from a single center

(2016) Riccardo Giannini et al.   ONCOLOGY REPORTS

Genomic Classification of Cutaneous Melanoma

(2015) Rehan Akbani et al.   CELL

Correlation of BRAF Mutation Status in Circulating-Free DNA and Tumor and Association with Clinical Outcome across Four BRAFi and MEKi Clinical Trials

(2015) A. Santiago-Walker et al.   CLINICAL CANCER RESEARCH

Detection of KRAS, NRAS and BRAF by mass spectrometry - a sensitive, reliable, fast and cost-effective technique

(2015) Mark Kriegsmann et al.   Diagnostic Pathology

Recurrent inactivating RASA2 mutations in melanoma

(2015) Rand Arafeh et al.   NATURE GENETICS

Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma

(2015) Elin S. Gray et al.   Oncotarget

Methylation-capture and Next-Generation Sequencing of free circulating DNA from human plasma

(2014) Kristina Warton et al.   BMC GENOMICS

Quantitative Cell-Free Circulating BRAFV600E Mutation Analysis by Use of Droplet Digital PCR in the Follow-up of Patients with Melanoma Being Treated with BRAF Inhibitors

(2014) M. F. Sanmamed et al.   CLINICAL CHEMISTRY

Age-related mutations associated with clonal hematopoietic expansion and malignancies

(2014) Mingchao Xie et al.   NATURE MEDICINE

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

(2014) Giulio Genovese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

(2014) Siddhartha Jaiswal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Telomerase reverse transcriptase promoter mutations in primary cutaneous melanoma

(2014) Barbara Heidenreich et al.   Nature Communications

TERT Promoter Mutations in Familial and Sporadic Melanoma

(2013) S. Horn et al.   SCIENCE

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

A Landscape of Driver Mutations in Melanoma

(2012) Eran Hodis et al.   CELL

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery