Excess Rab4 rescues synaptic and behavioral dysfunction caused by defective HTT-Rab4 axonal transport in Huntington’s disease

The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within Axons

(2020) Eric N. Anderson et al.   Frontiers in Cellular Neuroscience

Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of Huntingtin

(2020) Julie Bruyère et al.   eLife

Retrograde trafficking and quality control of yeast synaptobrevin, Snc1, are conferred by its transmembrane domain

(2019) Mengxiao Ma et al.   MOLECULAR BIOLOGY OF THE CELL

SGIP1α functions as a selective endocytic adaptor for the internalization of synaptotagmin 1 at synapses

(2019) Sang-Eun Lee et al.   Molecular Brain

SNAREs define targeting specificity of trafficking vesicles by combinatorial interaction with tethering factors

(2019) Seiichi Koike et al.   Nature Communications

The presenilin loop region is essential for glycogen synthase kinase 3 β (GSK3β) mediated functions on motor proteins during axonal transport

(2018) Rupkatha Banerjee et al.   HUMAN MOLECULAR GENETICS

Comparative Analysis of Mutant Huntingtin Binding Partners in Yeast Species

(2018) Yanding Zhao et al.   Scientific Reports

Loss of Huntingtin stimulates capture of retrograde dense-core vesicles to increase synaptic neuropeptide stores

(2017) Dinara Bulgari et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Two kinesins drive anterograde neuropeptide transport

(2017) Angeline Lim et al.   MOLECULAR BIOLOGY OF THE CELL

Compartmentalized Signaling in Neurons: From Cell Biology to Neuroscience

(2017) Marco Terenzio et al.   NEURON

Anterograde Transport of Rab4-Associated Vesicles Regulates Synapse Organization in Drosophila

(2017) Swagata Dey et al.   Cell Reports

Characterization of axonal transport defects in Drosophila Huntingtin mutants

(2016) Kurt R. Weiss et al.   JOURNAL OF NEUROGENETICS

Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport

(2016) María-Victoria Hinckelmann et al.   Nature Communications

An automated system for quantitative analysis of Drosophila larval locomotion

(2015) Boanerges Aleman-Meza et al.   BMC DEVELOPMENTAL BIOLOGY

Kinesin superfamily proteins (KIFs): Various functions and their relevance for important phenomena in life and diseases

(2015) Nobutaka Hirokawa et al.   EXPERIMENTAL CELL RESEARCH

Huntingtin differentially regulates the axonal transport of a sub-set of Rab-containing vesiclesin vivo

(2015) Joseph A. White et al.   HUMAN MOLECULAR GENETICS

Selective Microtubule-Based Transport of Dendritic Membrane Proteins Arises in Concert with Axon Specification

(2014) J. D. Petersen et al.   JOURNAL OF NEUROSCIENCE

Rab5 and Rab4 Regulate Axon Elongation in the Xenopus Visual System

(2014) J. Falk et al.   JOURNAL OF NEUROSCIENCE

Disruption of Axonal Transport Perturbs Bone Morphogenetic Protein (BMP) - Signaling and Contributes to Synaptic Abnormalities in Two Neurodegenerative Diseases

(2014) Min Jung Kang et al.   PLoS One

Syntaxin 17

(2013) Eisuke Itakura et al.   Autophagy

Modeling Huntington disease inDrosophila

(2013) Megan Krench et al.   FLY

Presenilin influences glycogen synthase kinase-3 β (GSK-3β) for kinesin-1 and dynein function during axonal transport

(2013) Kunsang Dolma et al.   HUMAN MOLECULAR GENETICS

Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo

(2013) Shermali Gunawardena et al.   HUMAN MOLECULAR GENETICS

Mutant Huntingtin Alters Retrograde Transport of TrkB Receptors in Striatal Dendrites

(2013) G. Liot et al.   JOURNAL OF NEUROSCIENCE

Huntingtin’s Function in Axonal Transport Is Conserved in Drosophila melanogaster

(2013) Diana Zala et al.   PLoS One

Cytoplasmic dynein heavy chain: the servant of many masters

(2013) Giampietro Schiavo et al.   TRENDS IN NEUROSCIENCES

Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease

(2012) Joern R. Steinert et al.   HUMAN MOLECULAR GENETICS

Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila

(2012) Gerald F. Reis et al.   MOLECULAR BIOLOGY OF THE CELL

In-vivo evidence for the disruption of Rab11 vesicle transport by loss of huntingtin

(2012) Derek Power et al.   NEUROREPORT

Subpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles

(2012) L. Szpankowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spastic Paraplegia Mutation N256S in the Neuronal Microtubule Motor KIF5A Disrupts Axonal Transport in a Drosophila HSP Model

(2012) Petra Füger et al.   PLoS Genetics

Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease

(2011) P Richards et al.   CELL DEATH AND DIFFERENTIATION

Huntingtin Aggregation Kinetics and Their Pathological Role in a Drosophila Huntington’s Disease Model

(2011) Kurt R. Weiss et al.   GENETICS

Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model

(2009) S. Zhang et al.   Disease Models & Mechanisms

APP Anterograde Transport Requires Rab3A GTPase Activity for Assembly of the Transport Vesicle

(2009) A. Szodorai et al.   JOURNAL OF NEUROSCIENCE

Mutant Huntingtin Impairs Vesicle Formation from Recycling Endosomes by Interfering with Rab11 Activity

(2009) X. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin

(2009) Gerardo A Morfini et al.   NATURE NEUROSCIENCE

The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling

(2008) E. Schonteich et al.   JOURNAL OF CELL SCIENCE

Enhanced Sensitivity of Striatal Neurons to Axonal Transport Defects Induced by Mutant Huntingtin

(2008) L.-S. Her et al.   JOURNAL OF NEUROSCIENCE

A function of huntingtin in guanine nucleotide exchange on Rab11

(2008) Xueyi Li et al.   NEUROREPORT