Critical Role for the NLRP3 Inflammasome in Mediating IL-1β Production in Shigella sonnei-Infected Macrophages

Application of immobilized ATP to the study of NLRP inflammasomes

(2019) Kuo-Chieh Liao et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Human intestinal enteroids as a model system of Shigella pathogenesis

(2019) Benjamin J. Koestler et al.   INFECTION AND IMMUNITY

Repurposing drugs targeting the P2X7 receptor to limit hyperinflammation and disease during influenza virus infection

(2019) Sarah Rosli et al.   BRITISH JOURNAL OF PHARMACOLOGY

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

(2019) Nathan Kelley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis

(2019) Juan José Martínez-García et al.   Nature Communications

Non-canonical NLRP3 inflammasome activation and IL-1β signaling are necessary to L. amazonensis control mediated by P2X7 receptor and leukotriene B4

(2019) Mariana M. Chaves et al.   PLoS Pathogens

The Secreted Virulence Factor NADase of Group A Streptococcus Inhibits P2X7 Receptor-Mediated Release of IL-1β

(2019) Elsa Westerlund et al.   Frontiers in Immunology

Mechanistic Insight Into the Activation of the NLRP3 Inflammasome by Neisseria gonorrhoeae in Macrophages

(2019) Lan-Hui Li et al.   Frontiers in Immunology

P2X7 receptor: A potential therapeutic target for autoimmune diseases

(2019) Fan Cao et al.   AUTOIMMUNITY REVIEWS

Shigella sonnei O-Antigen Inhibits Internalization, Vacuole Escape, and Inflammasome Activation

(2019) Jayne L. Watson et al.   mBio

Disparities in severe shigellosis among adults — Foodborne diseases active surveillance network, 2002–2014

(2018) Lindsey S. McCrickard et al.   BMC PUBLIC HEALTH

P2X7 Receptor-Associated Programmed Cell Death in the Pathophysiology of Hemorrhagic Stroke

(2018) Hengli Zhao et al.   Current Neuropharmacology

Shigellosis

(2018) Karen L Kotloff et al.   LANCET

Shigellosis outbreak among MSM living with HIV: a case–control study in Taiwan, 2015–2016

(2018) Hao-Hsin Wu et al.   SEXUALLY TRANSMITTED INFECTIONS

Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by Mycobacterium tuberculosis in Infected Macrophages

(2018) Eduardo P. Amaral et al.   Frontiers in Immunology

Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990–2016

(2018) Ibrahim A Khalil et al.   LANCET INFECTIOUS DISEASES

Effects of a pathogenic ETEC strain and a probiotic Enterococcus faecium strain on the inflammasome response in porcine dendritic cells

(2018) Henriette Loss et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses

(2018) Damien Bierschenk et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inflammatory Bowel Disease and the NLRP3 Inflammasome

(2017) Thirumala-Devi Kanneganti   NEW ENGLAND JOURNAL OF MEDICINE

NLRP3 inflammasome: Pathogenic role and potential therapeutic target for IgA nephropathy

(2017) Yu-Ling Tsai et al.   Scientific Reports

A GalNAc/Gal-specific lectin from the sea mussel Crenomytilus grayanus modulates immune response in macrophages and in mice

(2017) Oleg V. Chernikov et al.   Scientific Reports

P2X7 Receptor Induces Tumor Necrosis Factor-α Converting Enzyme Activation and Release to Boost TNF-α Production

(2017) Maria Barberà-Cremades et al.   Frontiers in Immunology

The worldwide spread of ciprofloxacin-resistant Shigella sonnei among HIV-infected men who have sex with men, Taiwan

(2016) C.-S. Chiou et al.   CLINICAL MICROBIOLOGY AND INFECTION

Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice

(2016) Yue Zhao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammasomes and Their Role in Innate Immunity of Sexually Transmitted Infections

(2016) Vivek Verma et al.   Frontiers in Immunology

Shigellosis in Subjects with Traveler's Diarrhea Versus Domestically Acquired Diarrhea: Implications for Antimicrobial Therapy and Human Immunodeficiency Virus Surveillance

(2015) Carlos Toro et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Type III Secretion Needle Proteins Induce Cell Signaling and Cytokine Secretion via Toll-Like Receptors

(2014) D. L. Jessen et al.   INFECTION AND IMMUNITY

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

(2014) Alberto Baroja-Mazo et al.   NATURE IMMUNOLOGY

ShigellaIpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages

(2014) Shiho Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shigella Type III Secretion Protein MxiI Is Recognized by Naip2 to Induce Nlrc4 Inflammasome Activation Independently of Pkcδ

(2014) Shiho Suzuki et al.   PLoS Pathogens

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

(2013) Raúl Muñoz-Planillo et al.   IMMUNITY

Intracellular Shigella remodels its LPS to dampen the innate immune recognition and evade inflammasome activation

(2013) I. Paciello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation

(2013) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subversion of inflammasome activation and pyroptosis by pathogenic bacteria

(2013) Larissa D. Cunha et al.   Frontiers in Cellular and Infection Microbiology

Shifting dominance of Shigella species in men who have sex with men

(2012) R. RATNAYAKE et al.   EPIDEMIOLOGY AND INFECTION

Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase-1-mediated interleukin-1β secretion

(2012) Pei-Chun Liao et al.   INFLAMMATION RESEARCH

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

(2012) Mélanie Bruchard et al.   NATURE MEDICINE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Inflammasomes: too big to miss

(2009) Andrea Stutz et al.   JOURNAL OF CLINICAL INVESTIGATION

Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome

(2009) Joseph A. Duncan et al.   JOURNAL OF IMMUNOLOGY