Type III Secretion Needle Proteins Induce Cell Signaling and Cytokine Secretion via Toll-Like Receptors

A Mutant with Aberrant Extracellular LcrV-YscF Interactions Fails To Form Pores and Translocate Yop Effector Proteins but Retains the Ability To Trigger Yop Secretion in Response to Host Cell Contact

(2013) D. E. Harmon et al.   JOURNAL OF BACTERIOLOGY

Cutting Edge: Mouse NAIP1 Detects the Type III Secretion System Needle Protein

(2013) M. Rayamajhi et al.   JOURNAL OF IMMUNOLOGY

Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation

(2013) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Common Structural Architecture of Shigella flexneri and Salmonella typhimurium Type Three Secretion Needles

(2013) Jean-Philippe Demers et al.   PLoS Pathogens

Toll-like receptors (TLR2 and TLR4) recognize polysaccharides of Pseudallescheria boydii cell wall

(2012) Rodrigo Tinoco Figueiredo et al.   CARBOHYDRATE RESEARCH

The NLRP12 Inflammasome Recognizes Yersinia pestis

(2012) Gregory I. Vladimer et al.   IMMUNITY

Atomic model of the type III secretion system needle

(2012) Antoine Loquet et al.   NATURE

Respiratory Syncytial Virus Fusion Protein-Induced Toll-Like Receptor 4 (TLR4) Signaling Is Inhibited by the TLR4 Antagonists Rhodobacter sphaeroides Lipopolysaccharide and Eritoran (E5564) and Requires Direct Interaction with MD-2

(2012) P. Rallabhandi et al.   mBio

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

Role of immune response in Yersinia pestis infection

(2011) Amedeo Amedei et al.   Journal of Infection in Developing Countries

Multi-Functional Characteristics of the Pseudomonas aeruginosa Type III Needle-Tip Protein, PcrV; Comparison to Orthologs in other Gram-negative Bacteria

(2011) Hiromi Sato et al.   Frontiers in Microbiology

The search for early markers of plague: evidence for accumulation of solubleYersinia pestisLcrV in bubonic and pneumonic mouse models of disease

(2010) Yehuda Flashner et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Innate Immune Detection of Bacterial Virulence Factors Via the NLRC4 Inflammasome

(2010) Edward A. Miao et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Imaging the assembly, structure and activity of type III secretion systems

(2009) Jost Enninga et al.   CELLULAR MICROBIOLOGY

Tetraacylated Lipopolysaccharide ofYersinia pestisCan Inhibit Multiple Toll‐Like Receptor–Mediated Signaling Pathways in Human Dendritic Cells

(2009) Maxim V. Telepnev et al.   JOURNAL OF INFECTIOUS DISEASES

Interaction between Ebola Virus Glycoprotein and Host Toll-Like Receptor 4 Leads to Induction of Proinflammatory Cytokines and SOCS1

(2009) A. Okumura et al.   JOURNAL OF VIROLOGY

YopR impacts type III needle polymerization inYersiniaspecies

(2009) Bill Blaylock et al.   MOLECULAR MICROBIOLOGY

TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensis

(2008) Amit R. Ashtekar et al.   JOURNAL OF LEUKOCYTE BIOLOGY

What's the point of the type III secretion system needle?

(2008) A. J. Blocker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA