The Gut Microbiota and Respiratory Diseases: New Evidence

Fecal dysbiosis in infants with cystic fibrosis is associated with early linear growth failure

(2020) Hillary S. Hayden et al.   NATURE MEDICINE

Interactions between the gut microbiome and host gene regulation in cystic fibrosis

(2020) Gargi Dayama et al.   Genome Medicine

Impact of fecal microbiota transplantation on TGF-β1/Smads/ERK signaling pathway of endotoxic acute lung injury in rats

(2020) Bo Li et al.   3 Biotech

The distribution characteristics of intestinal microbiota in children with community-acquired pneumonia under five Years of age

(2020) Xiaomeng Ren et al.   MICROBIAL PATHOGENESIS

Impact of prior antibiotic use on the efficacy of nivolumab for non‑small cell lung cancer

(2019) Taiki Hakozaki et al.   Oncology Letters

Alterations in the gut microbiota of patients with silica-induced pulmonary fibrosis

(2019) Yao Zhou et al.   Journal of Occupational Medicine and Toxicology

Probiotics in late infancy reduce the incidence of eczema: A randomized controlled trial

(2019) Rikke Meineche Schmidt et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Early-life vancomycin treatment promotes airway inflammation and impairs microbiome homeostasis

(2019) Xin Yang et al.   Aging-US

The diversity of gut microbiome is associated with favorable responses to anti-PD-1 immunotherapy in Chinese non-small cell lung cancer patients

(2019) Yueping Jin et al.   Journal of Thoracic Oncology

Dysbiosis of the Gut Microbiome in Lung Cancer

(2019) He Zhuang et al.   Frontiers in Cellular and Infection Microbiology

Intestinal Inflammation in Children with Cystic Fibrosis Is Associated with Crohn’s-Like Microbiota Disturbances

(2019) Raphaël Enaud et al.   Journal of Clinical Medicine

Early antibiotic exposure and development of asthma and allergic rhinitis in childhood

(2019) Jeffrey Ni et al.   BMC Pediatrics

Altered Stool Microbiota of Infants with Cystic Fibrosis Shows a Reduction in Genera Associated with Immune Programming from Birth

(2019) Katherine M. Antosca et al.   JOURNAL OF BACTERIOLOGY

Immunomodulatory and prophylactic effects of Bifidobacterium bifidum probiotic strain on influenza infection in mice

(2019) Mehran Mahooti et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Gut Microbiota Regulates Mincle Mediated Activation of Lung Dendritic Cells to Protect Against Mycobacterium tuberculosis

(2019) Shikha Negi et al.   Frontiers in Immunology

Pulmonary Manifestations of Inflammatory Bowel Disease

(2019) Annie Massart et al.   AMERICAN JOURNAL OF MEDICINE

Immunomodulatory effects of Lactobacillus plantarum on inflammatory response induced by Klebsiella pneumoniae

(2019) Marjolaine Vareille-Delarbre et al.   INFECTION AND IMMUNITY

Association between inflammatory bowel disease and chronic obstructive pulmonary disease: a systematic review and meta-analysis

(2019) Gonzalo Labarca et al.   BMC Pulmonary Medicine

Lung Microbiome in Asthma: Current Perspectives

(2019) Konstantinos Loverdos et al.   Journal of Clinical Medicine

Gut Microbiota in Children With Cystic Fibrosis: A Taxonomic and Functional Dysbiosis

(2019) Michael J. Coffey et al.   Scientific Reports

Multispecies probiotics combination prevents ovalbumin-induced airway hyperreactivity in mice

(2018) Jui-Cheng Chen et al.   ALLERGOLOGIA ET IMMUNOPATHOLOGIA

Intranasal administration of probiotic Lactobacillus rhamnosus GG prevents birch pollen-induced allergic asthma in a murine model

(2018) Irina Spacova et al.   ALLERGY

Lung Microbiota Is Related to Smoking Status and to Development of Acute Respiratory Distress Syndrome in Critically Ill Trauma Patients

(2018) Ariane R. Panzer et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Negative association of antibiotics on clinical activity of immune checkpoint inhibitors in patients with advanced renal cell and non-small-cell lung cancer

(2018) L Derosa et al.   ANNALS OF ONCOLOGY

Could Fecal Transplantation Become Part of PD-1-Based Immunotherapy, Due to Effects of the Intestinal Microbiome?

(2018) Paolo Biancheri et al.   GASTROENTEROLOGY

Early-life antibiotics attenuate regulatory T cell generation and increase the severity of murine house dust mite-induced asthma

(2018) Alexander J. Adami et al.   PEDIATRIC RESEARCH

Long term extension of a randomised controlled trial of probiotics using electronic health records

(2018) Gareth Davies et al.   Scientific Reports

The role of the gut microbiome in systemic inflammatory disease

(2018) Jose C Clemente et al.   BMJ-British Medical Journal

The role of the gut microbiome in systemic inflammatory disease

(2018) Jose C Clemente et al.   BMJ-British Medical Journal

Gut Microbiota: An Integral Moderator in Health and Disease

(2018) Qingqing Feng et al.   Frontiers in Microbiology

Association Between Use of Acid-Suppressive Medications and Antibiotics During Infancy and Allergic Diseases in Early Childhood

(2018) Edward Mitre et al.   JAMA Pediatrics

Respiratory Disease following Viral Lung Infection Alters the Murine Gut Microbiota

(2018) Helen T. Groves et al.   Frontiers in Immunology

Intestinal Microbiota Disruption Reduces Regulatory T Cells and Increases Respiratory Viral Infection Mortality Through Increased IFNγ Production

(2018) Mitchell H. Grayson et al.   Frontiers in Immunology

A metagenome-wide association study of gut microbiota in asthma in UK adults

(2018) Qi Wang et al.   BMC MICROBIOLOGY

Probiotics supplementation in children with asthma: A systematic review and meta-analysis

(2018) Jilei Lin et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Effect of a Probiotic Preparation on Ventilator-Associated Pneumonia in Critically Ill Patients Admitted to the Intensive Care Unit: A Prospective Double-Blind Randomized Controlled Trial

(2018) Ata Mahmoodpoor et al.   NUTRITION IN CLINICAL PRACTICE

The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice

(2018) Thomas Secher et al.   Scientific Reports

Bifidobacterium breve MRx0004 protects against airway inflammation in a severe asthma model by suppressing both neutrophil and eosinophil lung infiltration

(2018) Emma J. Raftis et al.   Scientific Reports

Diet, Microbiota and Gut-Lung Connection

(2018) Swadha Anand et al.   Frontiers in Microbiology

Association between Cigarette Smoking Status and Composition of Gut Microbiota: Population-Based Cross-Sectional Study

(2018) Su Hwan Lee et al.   Journal of Clinical Medicine

The role of the lung microbiota and the gut-lung axis in respiratory infectious diseases

(2018) Alexia Dumas et al.   CELLULAR MICROBIOLOGY

Perinatal probiotic intervention prevented allergic disease in a Caesarean-delivered subgroup at 13-year follow-up

(2018) Sampo Kallio et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Management of Ventilator-Associated Pneumonia

(2018) Mark L. Metersky et al.   CLINICS IN CHEST MEDICINE

The Role of the Microbiome in Asthma: The Gut–Lung Axis

(2018) Franco Frati et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut microbiota signatures in cystic fibrosis: Loss of host CFTR function drives the microbiota enterophenotype

(2018) Pamela Vernocchi et al.   PLoS One

Efficacy of Lactobacillus Administration in School-Age Children with Asthma: A Randomized, Placebo-Controlled Trial

(2018) Chian-Feng Huang et al.   Nutrients

Whole Fruits and Fruit Fiber Emerging Health Effects

(2018) Mark Dreher   Nutrients

The Host Microbiota Contributes to Early Protection Against Lung Colonization by Mycobacterium tuberculosis

(2018) Alexia Dumas et al.   Frontiers in Immunology

Microbial balance in the intestinal microbiota and its association with diabetes, obesity and allergic disease

(2018) Pourya Gholizadeh et al.   MICROBIAL PATHOGENESIS

Gut microbiome contributes to impairment of immunity in pulmonary tuberculosis patients by alteration of butyrate and propionate producers

(2017) Abhijit Maji et al.   ENVIRONMENTAL MICROBIOLOGY

The intestinal microbiota: Antibiotics, colonization resistance, and enteric pathogens

(2017) Sohn Kim et al.   IMMUNOLOGICAL REVIEWS

Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation

(2017) Jonathan U. Peled et al.   JOURNAL OF CLINICAL ONCOLOGY

Lactobacillus gasseri attenuates allergic airway inflammation through PPARγ activation in dendritic cells

(2017) Miao-Hsi Hsieh et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Diet and Respiratory Health in Children from 11 Latin American Countries: Evidence from ISAAC Phase III

(2017) Alfonso Mario Cepeda et al.   LUNG

Microbiome-driven allergic lung inflammation is ameliorated by short-chain fatty acids

(2017) A Cait et al.   Mucosal Immunology

Breastfeeding is associated with a decreased risk of childhood asthma exacerbations later in life

(2017) Fariba Ahmadizar et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Oral administration of Saccharomyces cerevisiae UFMG A-905 prevents allergic asthma in mice

(2017) Vanessa M.B. Fonseca et al.   RESPIROLOGY

Oral administration of Clostridium butyricum CGMCC0313-1 reduces ovalbumin-induced allergic airway inflammation in mice

(2017) Zhang Juan et al.   RESPIROLOGY

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Intestinal commensal bacteria mediate lung mucosal immunity and promote resistance of newborn mice to infection

(2017) Jerilyn Gray et al.   Science Translational Medicine

The microbiota protects against respiratory infection via GM-CSF signaling

(2017) Rebecca L. Brown et al.   Nature Communications

Probiotics for Preventing Ventilator-Associated Pneumonia in Mechanically Ventilated Patients: A Meta-Analysis with Trial Sequential Analysis

(2017) Hong Weng et al.   Frontiers in Pharmacology

Alternation of Gut Microbiota in Patients with Pulmonary Tuberculosis

(2017) Mei Luo et al.   Frontiers in Physiology

Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy

(2017) Sivaranjani Namasivayam et al.   Microbiome

Desired Turbulence? Gut-Lung Axis, Immunity, and Lung Cancer

(2017) Rea Bingula et al.   Journal of Oncology

Antibiotic treatment for Tuberculosis induces a profound dysbiosis of the microbiome that persists long after therapy is completed

(2017) Matthew F. Wipperman et al.   Scientific Reports

Recommending Oral Probiotics to Reduce Winter Antibiotic Prescriptions in People With Asthma: A Pragmatic Randomized Controlled Trial

(2016) T. D. H. Smith et al.   ANNALS OF FAMILY MEDICINE

The Microbiome and the Respiratory Tract

(2016) Robert P. Dickson et al.   Annual Review of Physiology

Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

(2016) Romain Daillère et al.   IMMUNITY

Clinical and metabolic response to probiotic supplementation in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial

(2016) Batol Zamani et al.   International Journal of Rheumatic Diseases

Effects of immunomodulatory supplementation with Lactobacillus rhamnosus on airway inflammation in a mouse asthma model

(2016) Chia-Ta Wu et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Microbiota and chronic inflammatory arthritis: an interwoven link

(2016) Andrea Picchianti Diamanti et al.   Journal of Translational Medicine

Control of Klebsiella pneumoniae pulmonary infection and immunomodulation by oral treatment with the commensal probiotic Bifidobacterium longum 5 1A

(2016) Angélica T. Vieira et al.   MICROBES AND INFECTION

Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation

(2016) Kei E Fujimura et al.   NATURE MEDICINE

Emerging pathogenic links between microbiota and the gut–lung axis

(2016) Kurtis F. Budden et al.   NATURE REVIEWS MICROBIOLOGY

Inflammatory bowel disease and airway diseases

(2016) Maria Vutcovici et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Streptomycin treatment alters the intestinal microbiome, pulmonary T cell profile and airway hyperresponsiveness in a cystic fibrosis mouse model

(2016) Mark Bazett et al.   Scientific Reports

Alteration in the Gut Microbiota Provokes Susceptibility to Tuberculosis

(2016) Nargis Khan et al.   Frontiers in Immunology

The lung microbiota in early rheumatoid arthritis and autoimmunity

(2016) Jose U. Scher et al.   Microbiome

Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome

(2016) Robert P. Dickson et al.   Nature Microbiology

Colonization of germ-free mice with a mixture of three lactobacillus strains enhances the integrity of gut mucosa and ameliorates allergic sensitization

(2015) Hana Kozakova et al.   Cellular & Molecular Immunology

Gut microbiota and obesity

(2015) Philippe Gérard   CELLULAR AND MOLECULAR LIFE SCIENCES

Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut

(2015) Liesbeth Allais et al.   ENVIRONMENTAL MICROBIOLOGY

Recurrent antibiotic exposure may promote cancer formation – Another step in understanding the role of the human microbiota?

(2015) Ben Boursi et al.   EUROPEAN JOURNAL OF CANCER

Well-balanced commensal microbiota contributes to anti-cancer response in a lung cancer mouse model

(2015) Q.-F. Gui et al.   GENETICS AND MOLECULAR RESEARCH

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

(2015) Tim J Schuijt et al.   GUT

Intestinal Microbiota of Mice Influences Resistance to Staphylococcus aureus Pneumonia

(2015) Stefanie Gauguet et al.   INFECTION AND IMMUNITY

Perinatal antibiotic-induced shifts in gut microbiota have differential effects on inflammatory lung diseases

(2015) Shannon L. Russell et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Associations between Gut Microbial Colonization in Early Life and Respiratory Outcomes in Cystic Fibrosis

(2015) Anne G. Hoen et al.   JOURNAL OF PEDIATRICS

Consecutive oral administration ofBifidobacterium longumMM-2 improves the defense system against influenza virus infection by enhancing natural killer cell activity in a murine model

(2015) Tomohiro Kawahara et al.   MICROBIOLOGY AND IMMUNOLOGY

The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment

(2015) Xuan Zhang et al.   NATURE MEDICINE

Anti-Inflammatory Effects of Lactobacillus Rahmnosus and Bifidobacterium Breve on Cigarette Smoke Activated Human Macrophages

(2015) Esmaeil Mortaz et al.   PLoS One

Early infancy microbial and metabolic alterations affect risk of childhood asthma

(2015) Marie-Claire Arrieta et al.   Science Translational Medicine

Regulation of lung immunity and host defense by the intestinal microbiota

(2015) Derrick R. Samuelson et al.   Frontiers in Microbiology

The clinical significance of the gut microbiota in cystic fibrosis and the potential for dietary therapies

(2014) Li Li et al.   CLINICAL NUTRITION

The evolution of the hygiene hypothesis

(2014) Denise Daley   Current Opinion in Allergy and Clinical Immunology

Effects ofLactobacillus caseisupplementation on disease activity and inflammatory cytokines in rheumatoid arthritis patients: a randomized double-blind clinical trial

(2014) Beitullah Alipour et al.   International Journal of Rheumatic Diseases

Improvement of digestive health and reduction in proteobacterial populations in the gut microbiota of cystic fibrosis patients using a Lactobacillus reuteri probiotic preparation: A double blind prospective study

(2014) Rosa del Campo et al.   Journal of Cystic Fibrosis

Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell–dependent inflammation

(2014) Jian Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Disturbed Intestinal Integrity in Patients With COPD

(2013) Erica P.A. Rutten et al.   CHEST

Low gut microbiota diversity in early infancy precedes asthma at school age

(2013) T. R. Abrahamsson et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Analysis of Fecal Lactobacillus Community Structure in Patients with Early Rheumatoid Arthritis

(2013) Xiaofei Liu et al.   CURRENT MICROBIOLOGY

Oral administration ofLactobacillus brevisKB290 to mice alleviates clinical symptoms following influenza virus infection

(2013) N. Waki et al.   LETTERS IN APPLIED MICROBIOLOGY

A randomized, double-blinded, placebo-controlled pilot study of probiotics in active rheumatoid arthritis

(2013) Maria de los Angeles Pineda et al.   MEDICAL SCIENCE MONITOR

Smoking Cessation Induces Profound Changes in the Composition of the Intestinal Microbiota in Humans

(2013) Luc Biedermann et al.   PLoS One

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

(2013) S. Viaud et al.   SCIENCE

Oral administration of Enterococcus faecalis FK-23 suppresses Th17 cell development and attenuates allergic airway responses in mice

(2012) BEI ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Orally administered heat-killed Lactobacillus gasseri TMC0356 alters respiratory immune responses and intestinal microbiota of diet-induced obese mice

(2012) K. Yoda et al.   JOURNAL OF APPLIED MICROBIOLOGY

Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function

(2012) T. Olszak et al.   SCIENCE

Side-stream smoking reduces intestinal inflammation and increases expression of tight junction proteins

(2012) Hui Wang   WORLD JOURNAL OF GASTROENTEROLOGY

Dysregulation of Allergic Airway Inflammation in the Absence of Microbial Colonization

(2011) Tina Herbst et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Daily intake of Lactobacillus casei Shirota increases natural killer cell activity in smokers

(2011) Marcella Reale et al.   BRITISH JOURNAL OF NUTRITION

Treatment with specific prebiotics or probiotics prevents the development of lung emphysema in a mouse model of COPD

(2011) K.A.T. Verheijden⁎ et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy

(2011) Frederika A. van Nimwegen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transient TLR Activation Restores Inflammatory Response and Ability To Control Pulmonary Bacterial Infection in Germfree Mice

(2011) C. T. Fagundes et al.   JOURNAL OF IMMUNOLOGY

Airway inflammation in probiotic-treated children at 5 years

(2011) Anna K. Kukkonen et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Commensal Microflora Contribute to Host Defense Against Escherichia Coli Pneumonia Through Toll-Like Receptors

(2011) Lee-Wei Chen et al.   SHOCK

Efficacy of probiotic Lactobacillus GG on allergic sensitization and asthma in infants at risk

(2010) M. A. Rose et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

(2008) D Makrygiannakis et al.   ANNALS OF THE RHEUMATIC DISEASES