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Title
Lysine Acetyltransferase Inhibitors From Natural Sources
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-08-12
DOI
10.3389/fphar.2020.01243
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Note: Only part of the references are listed.- The Different Effects of Substrates and Nucleotides on the Complex Formation of ABC Transporters
- (2019) Francesco Fiorentino et al. STRUCTURE
- Structural Simplification of Natural Products
- (2019) Shengzheng Wang et al. CHEMICAL REVIEWS
- Epigenetic polypharmacology: A new frontier for epi-drug discovery
- (2019) Daniela Tomaselli et al. MEDICINAL RESEARCH REVIEWS
- Lysine Acetylation Goes Global: From Epigenetics to Metabolism and Therapeutics
- (2018) Ibraheem Ali et al. CHEMICAL REVIEWS
- Total Synthesis and Evaluation of B-Homo Palmatine and Berberine Derivatives as p300 Histone Acetyltransferase Inhibitors
- (2018) Zhongzhen Yang et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Lysine acetyltransferase inhibitors: structure–activity relationships and potential therapeutic implications
- (2018) Francesco Fiorentino et al. Future Medicinal Chemistry
- Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes
- (2018) Simon Poepsel et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes
- (2018) Simon Poepsel et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth
- (2018) Jonathan B. Baell et al. NATURE
- The Essential Medicinal Chemistry of Curcumin
- (2017) Kathryn M. Nelson et al. JOURNAL OF MEDICINAL CHEMISTRY
- Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours
- (2017) Loren M. Lasko et al. NATURE
- A 6-alkylsalicylate histone acetyltransferase inhibitor inhibits histone acetylation and pro-inflammatory gene expression in murine precision-cut lung slices
- (2017) Thea van den Bosch et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- PCAF inhibits hepatocellular carcinoma metastasis by inhibition of epithelial-mesenchymal transition by targeting Gli-1
- (2016) Qing Li et al. CANCER LETTERS
- MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria
- (2016) Aindrila Chatterjee et al. CELL
- The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair
- (2016) C Bassi et al. CELL DEATH AND DIFFERENTIATION
- Identification of new p300 histone acetyltransferase inhibitors from natural products by a customized virtual screening method
- (2016) Guo-Bo Li et al. RSC Advances
- Sirtuin functions and modulation: from chemistry to the clinic
- (2016) Vincenzo Carafa et al. Clinical Epigenetics
- Mass Spectrometry of Protein Complexes: From Origins to Applications
- (2015) Shahid Mehmood et al. Annual Review of Physical Chemistry
- hMOF (human males absent on the first), an oncogenic protein of human oral tongue squamous cell carcinoma, targetingEZH2(enhancer of zeste homolog 2)
- (2015) Qihong Li et al. CELL PROLIFERATION
- Protein Lysine Acetylation by p300/CBP
- (2015) Beverley M. Dancy et al. CHEMICAL REVIEWS
- Histone acetyltransferase PCAF regulates inflammatory molecules in the development of renal injury
- (2015) Jin Huang et al. Epigenetics
- Enzyme kinetics and inhibition of histone acetyltransferase KAT8
- (2015) Hannah Wapenaar et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The Histone Acetyltransferase GCN5 Expression Is Elevated and Regulated by c-Myc and E2F1 Transcription Factors in Human Colon Cancer
- (2015) Yan-Wei Yin et al. GENE EXPRESSION
- A Novel Cell-Permeable, Selective, and Noncompetitive Inhibitor of KAT3 Histone Acetyltransferases from a Combined Molecular Pruning/Classical Isosterism Approach
- (2015) Ciro Milite et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Role of Histone Acetyltransferases in Normal and Malignant Hematopoiesis
- (2015) Xiao-Jian Sun et al. Frontiers in Oncology
- Phytochemicals Perturb Membranes and Promiscuously Alter Protein Function
- (2014) Helgi I. Ingólfsson et al. ACS Chemical Biology
- Identification of Structural Features of 2-Alkylidene-1,3-Dicarbonyl Derivatives that Induce Inhibition and/or Activation of Histone Acetyltransferases KAT3B/p300 and KAT2B/PCAF
- (2014) Sabrina Castellano et al. ChemMedChem
- Quinoline-Based p300 Histone Acetyltransferase Inhibitors with Pro-apoptotic Activity in Human Leukemia U937 Cells
- (2014) Alessia Lenoci et al. ChemMedChem
- Naphthoquinone-mediated Inhibition of Lysine Acetyltransferase KAT3B/p300, Basis for Non-toxic Inhibitor Synthesis
- (2014) Mohankrishna Dalvoy Vasudevarao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Tubulin K40 acetylation is required for contact inhibition of proliferation and cell–substrate adhesion
- (2014) Andrea Aguilar et al. MOLECULAR BIOLOGY OF THE CELL
- HDAC and HAT Inhibitors Differently Affect Analgesia Mediated by Group II Metabotropic Glutamate Receptors
- (2014) Magda Zammataro et al. Molecular Pain
- Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
- (2014) Katrina J. Falkenberg et al. NATURE REVIEWS DRUG DISCOVERY
- Targeting bromodomains: epigenetic readers of lysine acetylation
- (2014) Panagis Filippakopoulos et al. NATURE REVIEWS DRUG DISCOVERY
- The growing landscape of lysine acetylation links metabolism and cell signalling
- (2014) Chunaram Choudhary et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- PCAF Improves Glucose Homeostasis by Suppressing the Gluconeogenic Activity of PGC-1α
- (2014) Cheng Sun et al. Cell Reports
- Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation
- (2014) Sarina Ravens et al. eLife
- Probing p300/CBP Associated Factor (PCAF)-Dependent Pathways with a Small Molecule Inhibitor
- (2013) Rahul Modak et al. ACS Chemical Biology
- The MYSTerious MOZ, a histone acetyltransferase with a key role in haematopoiesis
- (2013) Flor M. Perez-Campo et al. IMMUNOLOGY
- Lysine Acetyltransferase GCN5 Potentiates the Growth of Non-small Cell Lung Cancer via Promotion of E2F1, Cyclin D1, and Cyclin E1 Expression
- (2013) Long Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Novel Activator of CBP/p300 Acetyltransferases Promotes Neurogenesis and Extends Memory Duration in Adult Mice
- (2013) S. Chatterjee et al. JOURNAL OF NEUROSCIENCE
- Targeted delivery of curcumin for treating type 2 diabetes
- (2013) Muralidhara Rao Maradana et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Perspectives on natural product epigenetic modulators in chemical biology and medicine
- (2013) Fanny L. Cherblanc et al. NATURAL PRODUCT REPORTS
- Acetyltransferases (HATs) as Targets for Neurological Therapeutics
- (2013) Anne Schneider et al. Neurotherapeutics
- Isogarcinol Is a New Immunosuppressant
- (2013) Juren Cen et al. PLoS One
- Mutations in KAT6B, Encoding a Histone Acetyltransferase, Cause Genitopatellar Syndrome
- (2012) Philippe M. Campeau et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3
- (2012) Ian M. Love et al. CELL CYCLE
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- (2012) Antonio Castro-Castro et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Crystal Structures of Tubulin Acetyltransferase Reveal a Conserved Catalytic Core and the Plasticity of the Essential N Terminus
- (2012) Vasilisa Kormendi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Woong Park et al. MOLECULES
- Structure of the -tubulin acetyltransferase, TAT1, and implications for tubulin-specific acetylation
- (2012) D. R. Friedmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Atomic resolution structure of human -tubulin acetyltransferase bound to acetyl-CoA
- (2012) M. Taschner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Emerging Roles of Anacardic Acid and Its Derivatives: A Pharmacological Overview
- (2011) Mahadevappa Hemshekhar et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Delphinidin, a specific inhibitor of histone acetyltransferase, suppresses inflammatory signaling via prevention of NF-κB acetylation in fibroblast-like synoviocyte MH7A cells
- (2011) Ah-Reum Seong et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Activation of a Tip60/E2F1/ERCC1 network in human lung adenocarcinoma cells exposed to cisplatin
- (2011) Arnaud Van Den Broeck et al. CARCINOGENESIS
- Targeting of Histone Acetyltransferase p300 by Cyclopentenone Prostaglandin Δ12-PGJ2 through Covalent Binding to Cys1438
- (2011) Kodihalli C. Ravindra et al. CHEMICAL RESEARCH IN TOXICOLOGY
- 6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site
- (2011) Massimo Ghizzoni et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Natural Product Libraries to Accelerate the High-Throughput Discovery of Therapeutic Leads
- (2011) Tyler A. Johnson et al. JOURNAL OF NATURAL PRODUCTS
- Procyanidin B3, an inhibitor of histone acetyltransferase, enhances the action of antagonist for prostate cancer cells via inhibition of p300-dependent acetylation of androgen receptor
- (2010) Kyung-Chul Choi et al. BIOCHEMICAL JOURNAL
- Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative
- (2010) Massimo Ghizzoni et al. BIOORGANIC & MEDICINAL CHEMISTRY
- The p300/CBP - associated factor is frequently down-regulated in intestinal-type gastric carcinoma and constitutes a biomarker for clinical outcome
- (2010) Ming-Zhen Ying et al. CANCER BIOLOGY & THERAPY
- P300/CBP-associated factor regulates Y-box binding protein-1 expression and promotes cancer cell growth, cancer invasion and drug resistance
- (2010) Masaki Shiota et al. CANCER SCIENCE
- MYST-family histone acetyltransferases: beyond chromatin
- (2010) Vasileia Sapountzi et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Nitric Oxide-Mediated Histone Hyperacetylation in Oral Cancer: Target for a Water-Soluble HAT Inhibitor, CTK7A
- (2010) Mohammed Arif et al. CHEMISTRY & BIOLOGY
- Epigenetic modifications and human disease
- (2010) Anna Portela et al. NATURE BIOTECHNOLOGY
- The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors
- (2009) F. M. Perez-Campo et al. BLOOD
- Histone acetyl transferases as emerging drug targets
- (2009) Frank J. Dekker et al. DRUG DISCOVERY TODAY
- Inhibition of Lysine Acetyltransferase KAT3B/p300 Activity by a Naturally Occurring Hydroxynaphthoquinone, Plumbagin
- (2009) Kodihalli C. Ravindra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Currying the Heart: Curcumin and Cardioprotection
- (2009) Geetika Srivastava et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS
- Acetylation by GCN5 regulates CDC6 phosphorylation in the S phase of the cell cycle
- (2009) Roberta Paolinelli et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma
- (2009) C Zhu et al. ONCOGENE
- Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature
- (2008) Preetha Anand et al. BIOCHEMICAL PHARMACOLOGY
- Chemical mechanisms of histone lysine and arginine modifications
- (2008) Brian C. Smith et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases
- (2008) Gianluca Sbardella et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases
- (2008) Antonello Mai et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis of Benzamides Related to Anacardic Acid and Their Histone Acetyltransferase (HAT) Inhibitory Activities
- (2008) José A. Souto et al. ChemMedChem
- Epigenetic Multiple Ligands: Mixed Histone/Protein Methyltransferase, Acetyltransferase, and Class III Deacetylase (Sirtuin) Inhibitors
- (2008) Antonello Mai et al. JOURNAL OF MEDICINAL CHEMISTRY
- The structural basis of protein acetylation by the p300/CBP transcriptional coactivator
- (2008) Xin Liu et al. NATURE
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