Evidence for the Effectiveness of Remdesivir (GS-5734), a Nucleoside-Analog Antiviral Drug in the Inhibition of IK(M) or IK(DR) and in the Stimulation of IMEP

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(2020) Miguel Angel Martinez   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

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Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019‐nCoV

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

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Characterization in Dual Activation by Oxaliplatin, a Platinum-Based Chemotherapeutic Agent of Hyperpolarization-Activated Cation and Electroporation-Induced Currents

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Characterization of Convergent Suppression by UCL-2077 (3-(Triphenylmethylaminomethyl)pyridine), Known to Inhibit Slow Afterhyperpolarization, of erg-Mediated Potassium Currents and Intermediate-Conductance Calcium-Activated Potassium Channels

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Differential Inhibitory Actions of Multitargeted Tyrosine Kinase Inhibitors on Different Ionic Current Types in Cardiomyocytes

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The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus

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Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

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Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection

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Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

(2020) Timothy P. Sheahan et al.   Nature Communications

Remdesivir as a possible therapeutic option for the COVID-19

(2020) Jaffar A. Al-Tawfiq et al.   Travel Medicine and Infectious Disease

Drug treatment options for the 2019-new coronavirus (2019-nCoV)

(2020) Hongzhou Lu   BioScience Trends

Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies

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Assessment of Hypokalemia and Clinical Characteristics in Patients With Coronavirus Disease 2019 in Wenzhou, China

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Evidence for Effective Multiple K+-Current Inhibitions by Tolvaptan, a Non-peptide Antagonist of Vasopressin V2 Receptor

(2019) Te-Ling Lu et al.   Frontiers in Pharmacology

Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

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Advances in respiratory virus therapeutics – A meeting report from the 6th isirv Antiviral Group conference

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Concerted suppression of Ih and activation of IK(M) by ivabradine, an HCN-channel inhibitor, in pituitary cells and hippocampal neurons

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Therapeutic strategies to target the Ebola virus life cycle

(2019) Thomas Hoenen et al.   NATURE REVIEWS MICROBIOLOGY

Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase

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New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections

(2019) Erik De Clercq   Chemistry-An Asian Journal

New treatments for Ebola virus disease

(2019) Daniel R Lucey   BMJ-British Medical Journal

Evidence for the Capability of Roxadustat (FG-4592), an Oral HIF Prolyl-Hydroxylase Inhibitor, to Perturb Membrane Ionic Currents: An Unidentified yet Important Action

(2019) Wei-Ting Chang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Measles Encephalitis: Towards New Therapeutics

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High Effectiveness in Actions of Carfilzomib on Delayed-Rectifier K+ Current and on Spontaneous Action Potentials

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Characterization of the Inhibitory Effect of Gastrodigenin and Gastrodin on M-type K+ Currents in Pituitary Cells and Hippocampal Neurons

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In vitro electroporation detection methods – An overview

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The comprehensive electrophysiological study of curcuminoids on delayed-rectifier K + currents in insulin-secreting cells

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Common and diverse elements of ion channels and receptors underlying electrical activity in endocrine pituitary cells

(2018) Patrick A. Fletcher et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

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Antiviral activity of aconite alkaloids from Aconitum carmichaelii Debx

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Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

(2017) Timothy P. Sheahan et al.   Science Translational Medicine

GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo- and Paramyxoviruses

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Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

(2016) Travis K. Warren et al.   NATURE

Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current If: Novel electrophysiological insights and therapeutic potential

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PIN3 duplication may be partially responsible for TP53haploinsufficiency

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Stimulation of electroporation-induced inward currents in glioblastoma cell lines by the heat shock protein inhibitor AUY922

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Identification of Minuscule Inward Currents as Precursors to Membrane Electroporation-Induced Currents: Real-Time Prediction of Pore Appearance

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The effects of magnetite (Fe3O4) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH3) cells and in RAW 264.7 macrophages

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Investigations into the Correlation Properties of Membrane Electroporation-Induced Inward Currents: Prediction of Pore Formation

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Electroporation-Induced Inward Current in Voltage-Clamped Guinea Pig Ventricular Myocytes

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Inhibitory action of methadone and its metabolites on erg-mediated K+ current in GH3 pituitary tumor cells

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Electroporating Fields Target Oxidatively Damaged Areas in the Cell Membrane

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Characterization of aconitine-induced block of delayed rectifier K+ current in differentiated NG108-15 neuronal cells

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