TXNIP induces growth arrest and enhances ABT263‐induced apoptosis in mixed‐lineage leukemia‐rearranged acute myeloid leukemia cells

Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

(2018) William J. Sullivan et al.   CELL

Transcriptional activation by MLL fusion proteins in leukemogenesis

(2017) Akihiko Yokoyama   EXPERIMENTAL HEMATOLOGY

A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity

(2015) Shuxi Qiao et al.   Nature Communications

About-face on the metabolic side effects of rapamycin

(2015) Adam B. Salmon   Oncotarget

Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia

(2015) Pierre Sujobert et al.   Cell Reports

Thioredoxin interacting protein (TXNIP) is a novel tumor suppressor in thyroid cancer

(2014) Jennifer A Morrison et al.   Molecular Cancer

A dual role for autophagy in a murine model of lung cancer

(2014) Shuan Rao et al.   Nature Communications

Thioredoxin and thioredoxin-interacting protein as prognostic markers for gastric cancer recurrence

(2012) Jae Yun Lim   WORLD JOURNAL OF GASTROENTEROLOGY

The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML

(2011) J. Zhou et al.   BLOOD

Thioredoxin-interacting protein suppresses bladder carcinogenesis

(2011) Koji Nishizawa et al.   CARCINOGENESIS

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

Autophagy-deficient mice develop multiple liver tumors

(2011) A. Takamura et al.   GENES & DEVELOPMENT

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

(2011) Yoshihiro Inami et al.   JOURNAL OF CELL BIOLOGY

Physiological Relevance of Antioxid/Redox Genes; Learning from Genetically Modified Animals Guest Editor: Junichi FujiiThioredoxin binding protein (TBP)-2/Txnip and α-arrestin proteins in cancer and diabetes mellitus

(2011) Hiroshi Masutani et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

TXNIP potentiates Redd1-induced mTOR suppression through stabilization of Redd1

(2011) H-O Jin et al.   ONCOGENE

Randomized study of induction therapy comparing standard-dose idarubicin with high-dose daunorubicin in adult patients with previously untreated acute myeloid leukemia: the JALSG AML201 Study

(2010) S. Ohtake et al.   BLOOD

Vitamin D3 Upregulated Protein 1 Suppresses TNF- -Induced NF- B Activation in Hepatocarcinogenesis

(2010) H.-J. Kwon et al.   JOURNAL OF IMMUNOLOGY

Disruption of TBP-2 ameliorates insulin sensitivity and secretion without affecting obesity

(2010) Eiji Yoshihara et al.   Nature Communications

Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study

(2009) B. V. Balgobind et al.   BLOOD

PrognoScan: a new database for meta-analysis of the prognostic value of genes

(2009) Hideaki Mizuno et al.   BMC Medical Genomics

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor

(2008) C. Tse et al.   CANCER RESEARCH

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Dendritic cells derived from TBP-2-deficient mice are defective in inducing T cell responses

(2008) Aoi Son et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Vitamin D3 Induces Autophagy of Human Myeloid Leukemia Cells

(2008) Jianrong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY