Current and Potential New Targets in Systemic Sclerosis Therapy: a New Hope
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Current and Potential New Targets in Systemic Sclerosis Therapy: a New Hope
Authors
Keywords
-
Journal
Current Rheumatology Reports
Volume 22, Issue 8, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-06-20
DOI
10.1007/s11926-020-00918-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Role of Epigenetic Modifications in Systemic Sclerosis: A Druggable Target
- (2019) John Henderson et al. TRENDS IN MOLECULAR MEDICINE
- Outcomes of patients with systemic sclerosis treated with rituximab in contemporary practice: a prospective cohort study
- (2019) Muriel Elhai et al. ANNALS OF THE RHEUMATIC DISEASES
- Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease
- (2019) Oliver Distler et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nemolizumab in moderate to severe atopic dermatitis: An exploratory analysis of work productivity and activity impairment in a randomized phase II study
- (2019) Ryosuke Mihara et al. JOURNAL OF DERMATOLOGY
- Perspectives on the role of Wnt biology in cancer
- (2019) Christopher K. Mirabelli et al. Science Signaling
- Abatacept in Early Diffuse Cutaneous Systemic Sclerosis – Results of a Phase 2 Investigator‐Initiated, Multicenter, Double‐Blind Randomized Placebo‐Controlled Trial
- (2019) Dinesh Khanna et al. Arthritis & Rheumatology
- In vitro pharmacological effects of peficitinib on lymphocyte activation: a potential treatment for systemic sclerosis with JAK inhibitors
- (2019) Yukihiro Kitanaga et al. RHEUMATOLOGY
- Therapeutic interleukin-6 blockade reverses transforming growth factor-beta pathway activation in dermal fibroblasts: insights from the faSScinate clinical trial in systemic sclerosis
- (2018) Christopher P Denton et al. ANNALS OF THE RHEUMATIC DISEASES
- Dysregulation of the Wnt signaling pathway in South African patients with diffuse systemic sclerosis
- (2018) Jacqueline Frost et al. CLINICAL RHEUMATOLOGY
- The Nrf2-Antioxidant Response Element Signaling Pathway Controls Fibrosis and Autoimmunity in Scleroderma
- (2018) Niloufar Kavian et al. Frontiers in Immunology
- SAR156597 in idiopathic pulmonary fibrosis: a phase 2 placebo-controlled study (DRI11772)
- (2018) Ganesh Raghu et al. EUROPEAN RESPIRATORY JOURNAL
- Inhibition of β-Catenin Signaling in the Skin Rescues Cutaneous Adipogenesis in Systemic Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Trial of C-82
- (2017) Robert Lafyatis et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Systemic sclerosis
- (2017) Christopher P Denton et al. LANCET
- Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis
- (2017) David Lagares et al. Science Translational Medicine
- Activation of cannabinoid receptor type 2 by JWH133 alleviates bleomycin-induced pulmonary fibrosis in mice
- (2017) Qiang Fu et al. Oncotarget
- Pan PPAR agonist IVA337 is effective in prevention and treatment of experimental skin fibrosis
- (2016) Nadira Ruzehaji et al. ANNALS OF THE RHEUMATIC DISEASES
- Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial
- (2016) Dinesh Khanna et al. LANCET
- Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog
- (2016) Maria Edeling et al. Nature Reviews Nephrology
- Antifibrotic Therapies: Where Are We Now?
- (2016) Young Yoon et al. SEMINARS IN LIVER DISEASE
- Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis
- (2015) Jingang Huang et al. ANNALS OF THE RHEUMATIC DISEASES
- Sustained β-catenin activity in dermal fibroblasts promotes fibrosis by up-regulating expression of extracellular matrix protein-coding genes
- (2015) Emily Hamburg-Shields et al. JOURNAL OF PATHOLOGY
- Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis
- (2015) Katrin Palumbo-Zerr et al. NATURE MEDICINE
- Endocannabinoid signaling at the periphery: 50 years after THC
- (2015) Mauro Maccarrone et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Effects and safety of rituximab in systemic sclerosis: an analysis from the European Scleroderma Trial and Research (EUSTAR) group
- (2014) Suzana Jordan et al. ANNALS OF THE RHEUMATIC DISEASES
- Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor-β (TGF-β) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein
- (2014) Steven O'Reilly et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dose-escalation of human anti-interferon-α receptor monoclonal antibody MEDI-546 in subjects with systemic sclerosis: a phase 1, multicenter, open label study
- (2014) Avram Goldberg et al. ARTHRITIS RESEARCH & THERAPY
- Role of interleukin-13 in fibrosis, particularly systemic sclerosis
- (2013) Steven O'Reilly BIOFACTORS
- Treating skin and lung fibrosis in systemic sclerosis: a future filled with promise?
- (2013) Milos Antic et al. CURRENT OPINION IN PHARMACOLOGY
- Abatacept: A Review of its Use in the Management of Rheumatoid Arthritis
- (2013) Gillian M. Keating DRUGS
- Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial
- (2013) Gerd R Burmester et al. LANCET
- Clinical and pathological significance of interleukin 6 overexpression in systemic sclerosis
- (2012) Korsa Khan et al. ANNALS OF THE RHEUMATIC DISEASES
- Interleukin-13-producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis
- (2012) Patrizia Fuschiotti et al. ARTHRITIS AND RHEUMATISM
- Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells
- (2012) Jun Wei et al. ARTHRITIS AND RHEUMATISM
- Tumor necrosis factor-costimulated T lymphocytes from patients with systemic sclerosis trigger collagen production in fibroblasts
- (2012) Thomas Hügle et al. ARTHRITIS AND RHEUMATISM
- Interleukin-6, its role in fibrosing conditions
- (2012) Steven O’Reilly et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis
- (2012) T. Kisseleva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- T cells in systemic sclerosis: a reappraisal
- (2012) S. O'Reilly et al. RHEUMATOLOGY
- Blockade of Interleukin-6 Receptor Alleviates Disease in Mouse Model of Scleroderma
- (2011) Shun Kitaba et al. AMERICAN JOURNAL OF PATHOLOGY
- Platelet-derived serotonin links vascular disease and tissue fibrosis
- (2011) Clara Dees et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease
- (2011) Mohammad R Ebrahimkhani et al. NATURE MEDICINE
- The cannabinoid WIN55, 212-2 abrogates dermal fibrosis in scleroderma bleomycin model
- (2010) E. Balistreri et al. ANNALS OF THE RHEUMATIC DISEASES
- PPARγ Downregulation by TGFß in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis
- (2010) Jun Wei et al. PLoS One
- The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab
- (2010) Y. Shima et al. RHEUMATOLOGY
- Rosiglitazone Abrogates Bleomycin-Induced Scleroderma and Blocks Profibrotic Responses Through Peroxisome Proliferator-Activated Receptor-γ
- (2009) Minghua Wu et al. AMERICAN JOURNAL OF PATHOLOGY
- Peroxisome proliferator-activated receptor-γ abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator
- (2009) Asish K. Ghosh et al. FASEB JOURNAL
- Cannabinoids inhibit fibrogenesis in diffuse systemic sclerosis fibroblasts
- (2009) E. Garcia-Gonzalez et al. RHEUMATOLOGY
- Experience with rituximab in scleroderma: results from a 1-year, proof-of-principle study
- (2009) Dimitrios Daoussis et al. RHEUMATOLOGY
- Cellular and molecular mechanisms of fibrosis
- (2007) TA Wynn JOURNAL OF PATHOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started