Intracellular antibody immunity and its applications

Enhancing Antigen Cross-Presentation in Human Monocyte-Derived Dendritic Cells by Recruiting the Intracellular Fc Receptor TRIM21

(2019) Patricia M. L. Ng et al.   JOURNAL OF IMMUNOLOGY

Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection

(2019) Larisa I Labzin et al.   EMBO JOURNAL

Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs

(2019) Agata P. Zielinska et al.   CURRENT BIOLOGY

Targeted protein degradation: expanding the toolbox

(2019) Matthieu Schapira et al.   NATURE REVIEWS DRUG DISCOVERY

TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination

(2018) Maria Bottermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation

(2017) William A. McEwan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Swine TRIM21 restricts FMDV infection via an intracellular neutralization mechanism

(2016) Wenchun Fan et al.   ANTIVIRAL RESEARCH

Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21

(2015) Adam J. Fletcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus

(2015) Ruth E. Watkinson et al.   PLoS Pathogens

Structural insights into the TRIM family of ubiquitin E3 ligases

(2014) Yang Li et al.   CELL RESEARCH

Translocalized IgA mediates neutralization and stimulates innate immunity inside infected cells

(2014) Susanna R. Bidgood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21

(2013) William A McEwan et al.   NATURE IMMUNOLOGY

Intracellular antibody receptor TRIM21 prevents fatal viral infection

(2013) M. Vaysburd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Virus Neutralization and the Persistent Fraction by TRIM21

(2012) W. A. McEwan et al.   JOURNAL OF VIROLOGY

Adenovirus Serotype 5 Neutralizing Antibodies Target both Hexon and Fiber following Vaccination and Natural Infection

(2011) R. R. Bradley et al.   JOURNAL OF VIROLOGY

Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)

(2010) D. L. Mallery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiviral Antibodies Target Adenovirus to Phagolysosomes and Amplify the Innate Immune Response

(2009) A. K. Zaiss et al.   JOURNAL OF IMMUNOLOGY

Direct activation of protein kinases by unanchored polyubiquitin chains

(2009) Zong-Ping Xia et al.   NATURE

TRIM21 is an IgG receptor that is structurally, thermodynamically, and kinetically conserved

(2008) A. H. Keeble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA