TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus

Hepatitis A Virus 3C Protease Cleaves NEMO To Impair Induction of Beta Interferon

(2014) D. Wang et al.   JOURNAL OF VIROLOGY

Activation of the Interferon Induction Cascade by Influenza A Viruses Requires Viral RNA Synthesis and Nuclear Export

(2014) M. J. Killip et al.   JOURNAL OF VIROLOGY

Cytosolic-DNA-Mediated, STING-Dependent Proinflammatory Gene Induction Necessitates Canonical NF- B Activation through TBK1

(2014) T. Abe et al.   JOURNAL OF VIROLOGY

Intracellular sensing of complement C3 activates cell autonomous immunity

(2014) J. C. H. Tam et al.   SCIENCE

Tracking Viral Genomes in Host Cells at Single-Molecule Resolution

(2013) I-Hsuan Wang et al.   Cell Host & Microbe

The Capsids of HIV-1 and HIV-2 Determine Immune Detection of the Viral cDNA by the Innate Sensor cGAS in Dendritic Cells

(2013) Xavier Lahaye et al.   IMMUNITY

Simultaneous Neutralization and Innate Immune Detection of a Replicating Virus by TRIM21

(2013) R. E. Watkinson et al.   JOURNAL OF VIROLOGY

Adenovirus Detection by the cGAS/STING/TBK1 DNA Sensing Cascade

(2013) E. Lam et al.   JOURNAL OF VIROLOGY

HIV-1 evades innate immune recognition through specific cofactor recruitment

(2013) Jane Rasaiyaah et al.   NATURE

Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21

(2013) William A McEwan et al.   NATURE IMMUNOLOGY

Intracellular antibody receptor TRIM21 prevents fatal viral infection

(2013) M. Vaysburd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fates of Retroviral Core Components during Unrestricted and TRIM5-Restricted Infection

(2013) Sebla B. Kutluay et al.   PLoS Pathogens

Regulation of Virus Neutralization and the Persistent Fraction by TRIM21

(2012) W. A. McEwan et al.   JOURNAL OF VIROLOGY

Sensing Adenovirus Infection: Activation of Interferon Regulatory Factor 3 in RAW 264.7 Cells

(2012) Saskia C. Stein et al.   JOURNAL OF VIROLOGY

A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71

(2012) Xiangxi Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

AAA ATPase p97/VCP is essential for TRIM21-mediated virus neutralization

(2012) F. Hauler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenovirus Core Protein VII Protects the Viral Genome from a DNA Damage Response at Early Times after Infection

(2011) K. A. Karen et al.   JOURNAL OF VIROLOGY

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

(2011) Thomas Pertel et al.   NATURE

Human rhinovirus recognition in non-immune cells is mediated byToll-like receptors and MDA-5, which trigger a synergetic pro-inflammatory immune response

(2011) Kathy Triantafilou et al.   Virulence

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

(2010) Jan Rehwinkel et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)

(2010) D. L. Mallery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIGorous Detection: Exposing Virus Through RNA Sensing

(2010) J. Rehwinkel et al.   SCIENCE

Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium

(2010) Louise Slater et al.   PLoS Pathogens

RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway

(2009) Yu-Hsin Chiu et al.   CELL

Use of the Pharmacological Inhibitor BX795 to Study the Regulation and Physiological Roles of TBK1 and IκB Kinase ϵ

(2009) Kristopher Clark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RIG-I is cleaved during picornavirus infection

(2009) Paola M. Barral et al.   VIROLOGY

Nonviral Vectors for Gene Delivery

(2008) Meredith A. Mintzer et al.   CHEMICAL REVIEWS

Neutralizing Antibody Blocks Adenovirus Infection by Arresting Microtubule-Dependent Cytoplasmic Transport

(2008) J. G. Smith et al.   JOURNAL OF VIROLOGY