Beyond tug-of-war: Iron metabolism in cooperative host–microbe interactions

The Biology of Physiological Health

(2020) Janelle S. Ayres   CELL

Dendritic cell–derived hepcidin sequesters iron from the microbiota to promote mucosal healing

(2020) Nicholas J. Bessman et al.   SCIENCE

Bacterial siderophores in community and host interactions

(2019) Jos Kramer et al.   NATURE REVIEWS MICROBIOLOGY

Critical Role for the Microbiota in CX 3 CR1 + Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses

(2018) Myunghoo Kim et al.   IMMUNITY

Hepcidin Protects against Lethal Escherichia coli Sepsis in Mice Inoculated with Isolates from Septic Patients

(2018) Deborah Stefanova et al.   INFECTION AND IMMUNITY

Burkholderia pseudomallei modulates host iron homeostasis to facilitate iron availability and intracellular survival

(2018) Imke H. E. Schmidt et al.   PLoS Neglected Tropical Diseases

Microbial Siderophore Enterobactin Promotes Mitochondrial Iron Uptake and Development of the Host via Interaction with ATP Synthase

(2018) Bin Qi et al.   CELL

Cooperative Metabolic Adaptations in the Host Can Favor Asymptomatic Infection and Select for Attenuated Virulence in an Enteric Pathogen

(2018) Karina K. Sanchez et al.   CELL

Bacterial Siderophores Hijack Neutrophil Functions

(2017) Piu Saha et al.   JOURNAL OF IMMUNOLOGY

Cooperative Microbial Tolerance Behaviors in Host-Microbiota Mutualism

(2016) Janelle S. Ayres   CELL

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions

(2016) Rui Martins et al.   NATURE IMMUNOLOGY

Hepcidin-Induced Hypoferremia Is a Critical Host Defense Mechanism against the Siderophilic Bacterium Vibrio vulnificus

(2015) João Arezes et al.   Cell Host & Microbe

No Vacancy: How Beneficial Microbes Cooperate with Immunity To Provide Colonization Resistance to Pathogens

(2015) Martina Sassone-Corsi et al.   JOURNAL OF IMMUNOLOGY

Diverging roles of bacterial siderophores during infection

(2015) Victoria I. Holden et al.   Metallomics

Interplay between enterobactin, myeloperoxidase and lipocalin 2 regulates E. coli survival in the inflamed gut

(2015) Vishal Singh et al.   Nature Communications

Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man

(2014) Alexander Jais et al.   CELL

Rapid fucosylation of intestinal epithelium sustains host–commensal symbiosis in sickness

(2014) Joseph M. Pickard et al.   NATURE

Dietary Iron Overload Induces Visceral Adipose Tissue Insulin Resistance

(2013) Paola Dongiovanni et al.   AMERICAN JOURNAL OF PATHOLOGY

Iron in Infection and Immunity

(2013) James E. Cassat et al.   Cell Host & Microbe

Probiotic Bacteria Reduce Salmonella Typhimurium Intestinal Colonization by Competing for Iron

(2013) Elisa Deriu et al.   Cell Host & Microbe

Activation of Mitochondrial Biogenesis by Heme Oxygenase-1–mediated NF-E2–related Factor-2 Induction Rescues Mice from LethalStaphylococcusaureusSepsis

(2012) Nancy Chou MacGarvey et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Tolerance of Infections

(2012) Janelle S. Ayres et al.   Annual Review of Immunology

Nutritional immunity: transition metals at the pathogen–host interface

(2012) M. Indriati Hood et al.   NATURE REVIEWS MICROBIOLOGY

Hepcidin and the Iron-Infection Axis

(2012) H. Drakesmith et al.   SCIENCE

Malaria impairs resistance to Salmonella through heme- and heme oxygenase–dependent dysfunctional granulocyte mobilization

(2011) Aubrey J Cunnington et al.   NATURE MEDICINE

A Central Role for Free Heme in the Pathogenesis of Severe Sepsis

(2010) R. Larsen et al.   Science Translational Medicine

Heme oxygenase-1 affords protection against noncerebral forms of severe malaria

(2009) E. Seixas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Photolysis of iron-siderophore chelates promotes bacterial-algal mutualism

(2009) S. A. Amin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Iron depletion limits intracellular bacterial growth in macrophages

(2008) P. N. Paradkar et al.   BLOOD

Carbon Monoxide-releasing Antibacterial Molecules Target Respiration and Global Transcriptional Regulators

(2008) Kelly S. Davidge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decomposing health: tolerance and resistance to parasites in animals

(2008) L. Raberg et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES