Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli

Recruitment of MAIT Cells to the Intervillous Space of the Placenta by Placenta-Derived Chemokines

(2019) Martin Solders et al.   Frontiers in Immunology

The biology and functional importance of MAIT cells

(2019) Dale I. Godfrey et al.   NATURE IMMUNOLOGY

TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions

(2019) Tianqi Leng et al.   Cell Reports

Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality

(2019) Timothy S.C. Hinks et al.   Cell Reports

TCR- or Cytokine-Activated CD8+ Mucosal-Associated Invariant T Cells Are Rapid Polyfunctional Effectors That Can Coordinate Immune Responses

(2019) Rajesh Lamichhane et al.   Cell Reports

Epidemiology and Diagnostics of Carbapenem Resistance in Gram-negative Bacteria

(2019) Patrice Nordmann et al.   CLINICAL INFECTIOUS DISEASES

Granulysin: killer lymphocyte safeguard against microbes

(2019) Farokh Dotiwala et al.   CURRENT OPINION IN IMMUNOLOGY

MAIT cells are imprinted by the microbiota in early life and promote tissue repair

(2019) Michael G. Constantinides et al.   SCIENCE

IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection

(2019) Huimeng Wang et al.   Science Immunology

Tuning of human MAIT cell activation by commensal bacteria species and MR1-dependent T-cell presentation

(2018) Cihan Tastan et al.   Mucosal Immunology

MAIT cells protect against pulmonary Legionella longbeachae infection

(2018) Huimeng Wang et al.   Nature Communications

Integrated pharmacokinetic–pharmacodynamic modeling to evaluate empiric carbapenem therapy in bloodstream infections

(2018) Tze-Peng Lim et al.   Infection and Drug Resistance

Tissue-resident MAIT cell populations in human oral mucosa exhibit an activated profile and produce IL-17

(2018) Michał J. Sobkowiak et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The CD4−CD8− MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool

(2018) Joana Dias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mucosa-associated invariant T cells link intestinal immunity with antibacterial immune defects in alcoholic liver disease

(2017) Antonio Riva et al.   GUT

The Burden of Comorbidity Is Associated with Antibiotic Resistance Among Institutionalized Elderly with Urinary Infection: A Retrospective Cohort Study in a Single Italian Nursing Home Between 2009 and 2014

(2017) Alice Laudisio et al.   Microbial Drug Resistance

Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells

(2017) Jeffrey Y. W. Mak et al.   Nature Communications

MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype upon bacterial stimulation

(2017) Martin Solders et al.   Scientific Reports

MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression

(2017) Christopher R. Shaler et al.   PLOS BIOLOGY

Bacterial deception of MAIT cells in a cloud of superantigen and cytokines

(2017) Johan K. Sandberg et al.   PLOS BIOLOGY

Shared and Distinct Phenotypes and Functions of Human CD161++ Vα7.2+ T Cell Subsets

(2017) Ayako Kurioka et al.   Frontiers in Immunology

Demographic and infection characteristics of patients with carbapenem-resistant Enterobacteriaceae in a community hospital: Development of a bedside clinical score for risk assessment

(2016) Brooke M. Miller et al.   AMERICAN JOURNAL OF INFECTION CONTROL

MAIT, MR1, microbes and riboflavin: a paradigm for the co-evolution of invariant TCRs and restricting MHCI-like molecules?

(2016) Stanislas Mondot et al.   IMMUNOGENETICS

MAIT cells promote inflammatory monocyte differentiation into dendritic cells during pulmonary intracellular infection

(2016) Anda I. Meierovics et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human MAIT-cell responses to Escherichia coli : activation, cytokine production, proliferation, and cytotoxicity

(2016) Joana Dias et al.   JOURNAL OF LEUKOCYTE BIOLOGY

MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation

(2016) A Gibbs et al.   Mucosal Immunology

Antimicrobial Properties of an Immunomodulator - 15 kDa Human Granulysin

(2016) Hung-Mu Wei et al.   PLoS One

Carbapenem-resistant Enterobacteriaceae in special populations: Solid organ transplant recipients, stem cell transplant recipients, and patients with hematologic malignancies

(2016) Stephanie M. Pouch et al.   Virulence

Integrating Antimicrobial Therapy with Host Immunity to Fight Drug-Resistant Infections: Classical vs. Adaptive Treatment

(2016) Erida Gjini et al.   PLoS Computational Biology

Live cell evaluation of granzyme delivery and death receptor signaling in tumor cells targeted by human natural killer cells

(2015) A. C. Vrazo et al.   BLOOD

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

(2015) Isabelle Magalhaes et al.   JOURNAL OF CLINICAL INVESTIGATION

Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection

(2015) Edwin Leeansyah et al.   PLoS Pathogens

Extensive Identification of Bacterial Riboflavin Transporters and Their Distribution across Bacterial Species

(2015) Ana Gutiérrez-Preciado et al.   PLoS One

Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes

(2014) Michael Walch et al.   CELL

MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets

(2014) A Kurioka et al.   Mucosal Immunology

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

(2014) Alexandra J. Corbett et al.   NATURE

Comorbidities and Disease Severity as Risk Factors for Carbapenem-Resistant Klebsiella pneumoniae Colonization: Report of an Experience in an Internal Medicine Unit

(2014) Antonio Nouvenne et al.   PLoS One

Exploring the collaboration between antibiotics and the immune response in the treatment of acute, self-limiting infections

(2014) P. Ankomah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection

(2013) A. Meierovics et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MAIT Cells Detect and Efficiently Lyse Bacterially-Infected Epithelial Cells

(2013) Lionel Le Bourhis et al.   PLoS Pathogens

Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection

(2012) E. Leeansyah et al.   BLOOD

Polyclonal Mucosa-Associated Invariant T Cells Have Unique Innate Functions in Bacterial Infection

(2012) Wei-Jen Chua et al.   INFECTION AND IMMUNITY

MR1 presents microbial vitamin B metabolites to MAIT cells

(2012) Lars Kjer-Nielsen et al.   NATURE

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells

(2010) M. Dusseaux et al.   BLOOD

Biology and clinical relevance of granulysin

(2009) A. M. Krensky et al.   TISSUE ANTIGENS

Exploring the role of the immune response in preventing antibiotic resistance

(2008) Andreas Handel et al.   JOURNAL OF THEORETICAL BIOLOGY