Astaxanthin alleviates spinal cord ischemia-reperfusion injury via activation of PI3K/Akt/GSK-3β pathway in rats

Astaxanthin but not quercetin preserves mitochondrial integrity and function, ameliorates oxidative stress, and reduces heat-induced skeletal muscle injury

(2019) Tianzheng Yu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Potential Role of the NLRP3 Inflammasome Activation as a Link Between Mitochondria ROS Generation and Neuroinflammation in Postoperative Cognitive Dysfunction

(2019) Penghui Wei et al.   Frontiers in Cellular Neuroscience

Inhibition of NOX2 signaling limits pain-related behavior and improves motor function in male mice after spinal cord injury: Participation of IL-10/miR-155 pathways

(2019) Boris Sabirzhanov et al.   BRAIN BEHAVIOR AND IMMUNITY

Astaxanthin Complexes to Attenuate Muscle Damage after In Vivo Femoral Ischemia-Reperfusion

(2019) Marisol Zuluaga Tamayo et al.   Marine Drugs

The Neuroprotective Effects of Astaxanthin: Therapeutic Targets and Clinical Perspective

(2019) Fakhri et al.   MOLECULES

FGF10 Enhances Peripheral Nerve Regeneration via the Preactivation of the PI3K/Akt Signaling-Mediated Antioxidant Response

(2019) Lvpeng Dong et al.   Frontiers in Pharmacology

Astaxanthin-antioxidant impact on excessive Reactive Oxygen Species generation induced by ischemia and reperfusion injury

(2018) M. Zuluaga et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Neuroprotective Effects of Luteolin Against Spinal Cord Ischemia–Reperfusion Injury by Attenuation of Oxidative Stress, Inflammation, and Apoptosis

(2018) Jian Fu et al.   JOURNAL OF MEDICINAL FOOD

Astaxanthin ameliorates behavioral and biochemical alterations in in-vitro and in-vivo model of neuropathic pain

(2018) Kuhu Sharma et al.   NEUROSCIENCE LETTERS

Astaxanthin attenuates neuroinflammation contributed to the neuropathic pain and motor dysfunction following compression spinal cord injury

(2018) Sajad Fakhri et al.   BRAIN RESEARCH BULLETIN

On the Neuroprotective Role of Astaxanthin: New Perspectives?

(2018) Christian Galasso et al.   Marine Drugs

Astaxanthin: A mechanistic review on its biological activities and health benefits

(2018) Sajad Fakhri et al.   PHARMACOLOGICAL RESEARCH

Methane ameliorates spinal cord ischemia-reperfusion injury in rats: Antioxidant, anti-inflammatory and anti-apoptotic activity mediated by Nrf2 activation

(2017) Liping Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protective effect of nicotinamide adenine dinucleotide (NAD+) against spinal cord ischemia–reperfusion injury via reducing oxidative stress-induced neuronal apoptosis

(2017) Lei Xie et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Astaxanthin Ameliorates Doxorubicin-Induced Cognitive Impairment (Chemobrain) in Experimental Rat Model: Impact on Oxidative, Inflammatory, and Apoptotic Machineries

(2017) Sara Emad El-Agamy et al.   MOLECULAR NEUROBIOLOGY

Astaxanthin prevents ischemia-reperfusion injury of the steatotic liver in mice

(2017) Shaowei Li et al.   PLoS One

Neuron and microglia/macrophage-derived FGF10 activate neuronal FGFR2/PI3K/Akt signaling and inhibit microglia/macrophages TLR4/NF-κB-dependent neuroinflammation to improve functional recovery after spinal cord injury

(2017) Jian Chen et al.   Cell Death & Disease

Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration

(2017) Bethany Grimmig et al.   GeroScience

Inhibition of Mitochondrial Fission and NOX2 Expression Prevent NLRP3 Inflammasome Activation in the Endothelium: The Role of Corosolic Acid Action in the Amelioration of Endothelial Dysfunction

(2016) Yi Li et al.   ANTIOXIDANTS & REDOX SIGNALING

Rosuvastatin postconditioning protects isolated hearts against ischemia-reperfusion injury: The role of radical oxygen species, PI3K-Akt-GSK-3β pathway, and mitochondrial permeability transition pore

(2016) Chun-Wei Liu et al.   Cardiovascular Therapeutics

Neuroprotective effects of thymoquinone against spinal cord ischemia-reperfusion injury by attenuation of inflammation, oxidative stress, and apoptosis

(2016) Emre Cemal Gökce et al.   JOURNAL OF NEUROSURGERY-SPINE

Curcumin Attenuates Inflammation, Oxidative Stress, and Ultrastructural Damage Induced by Spinal Cord Ischemia–Reperfusion Injury in Rats

(2016) Emre Cemal Gokce et al.   Journal of Stroke & Cerebrovascular Diseases

Curcumin Attenuates Inflammation, Oxidative Stress, and Ultrastructural Damage Induced by Spinal Cord Ischemia–Reperfusion Injury in Rats

(2016) Emre Cemal Gokce et al.   Journal of Stroke & Cerebrovascular Diseases

Inhibition of NOX2 reduces locomotor impairment, inflammation, and oxidative stress after spinal cord injury

(2015) Guzal Khayrullina et al.   Journal of Neuroinflammation

Glucagon-like peptide-1 protects cardiomyocytes from advanced oxidation protein product-induced apoptosis via the PI3K/Akt/Bad signaling pathway

(2015) HUA ZHANG et al.   Molecular Medicine Reports

Effects of grape seed proanthocyanidin extract on pentylenetetrazole-induced kindling and associated cognitive impairment in rats

(2014) JUNLI ZHEN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Regulation of IL-10 by Chondroitinase ABC Promotes a Distinct Immune Response following Spinal Cord Injury

(2014) Athanasios Didangelos et al.   JOURNAL OF NEUROSCIENCE

Effects of Intravascular Laser Irradiation of Blood in Mitochondria Dysfunction and Oxidative Stress in Adults with Chronic Spinal Cord Injury

(2012) Shih-Fong Huang et al.   PHOTOMEDICINE AND LASER SURGERY

Metabolic and functional differences between brain and spinal cord mitochondria underlie different predisposition to pathology

(2011) Alexander V. Panov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Spinal cord complications after thoracic aortic surgery: Long-term survival and functional status varies with deficit severity

(2008) Mark F. Conrad et al.   JOURNAL OF VASCULAR SURGERY