FGF10 Enhances Peripheral Nerve Regeneration via the Preactivation of the PI3K/Akt Signaling-Mediated Antioxidant Response

Heparin-Poloxamer Thermosensitive Hydrogel Loaded with bFGF and NGF Enhances Peripheral Nerve Regeneration in Diabetic Rats

(2018) Rui Li et al.   BIOMATERIALS

NGF and PI3K/Akt signaling participate in the ventral motor neuronal protection of curcumin in sciatic nerve injury rat models

(2018) Qiuling Sang et al.   BIOMEDICINE & PHARMACOTHERAPY

Carboxymethylated chitosan protects Schwann cells against hydrogen peroxide-induced apoptosis by inhibiting oxidative stress and mitochondria dependent pathway

(2018) Bin He et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways

(2018) Hailong Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Selenizing astragalus polysaccharide attenuates PCV2 replication promotion caused by oxidative stress through autophagy inhibition via PI3K/AKT activation

(2018) Dandan Liu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Ganglioside GM1 protects against high altitude cerebral edema in rats by suppressing the oxidative stress and inflammatory response via the PI3K/AKT-Nrf2 pathway

(2018) Gu Gong et al.   MOLECULAR IMMUNOLOGY

Local low dose curcumin treatment improves functional recovery and remyelination in a rat model of sciatic nerve crush through inhibition of oxidative stress

(2018) Martial Caillaud et al.   NEUROPHARMACOLOGY

Dental pulp-derived stem cells can counterbalance peripheral nerve injury-induced oxidative stress and supraspinal neuro-inflammation in rat brain

(2018) Imran Ullah et al.   Scientific Reports

Fibroblast growth factor 21 facilitates peripheral nerve regeneration through suppressing oxidative damage and autophagic cell death

(2018) Yingfeng Lu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Carnosine improves functional recovery and structural regeneration after sciatic nerve crush injury in rats

(2018) Navideh Mirzakhani et al.   LIFE SCIENCES

FGF10 Protects Against Renal Ischemia/Reperfusion Injury by Regulating Autophagy and Inflammatory Signaling

(2018) Xiaohua Tan et al.   Frontiers in Genetics

Single injection of a novel nerve growth factor coacervate improves structural and functional regeneration after sciatic nerve injury in adult rats

(2017) Rui Li et al.   EXPERIMENTAL NEUROLOGY

Regulation mechanism of oxidative stress induced by high glucose through PI3K/Akt/Nrf2 pathway in juvenile blunt snout bream ( Megalobrama amblycephala )

(2017) Wenjing Pan et al.   FISH & SHELLFISH IMMUNOLOGY

Dual Delivery of NGF and bFGF Coacervater Ameliorates Diabetic Peripheral Neuropathy via Inhibiting Schwann Cells Apoptosis

(2017) Rui Li et al.   International Journal of Biological Sciences

Oil Body-Bound Oleosin-rhFGF-10: A Novel Drug Delivery System that Improves Skin Penetration to Accelerate Wound Healing and Hair Growth in Mice

(2017) Wenqing Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

FGF-dependent metabolic control of vascular development

(2017) Pengchun Yu et al.   NATURE

Neuron and microglia/macrophage-derived FGF10 activate neuronal FGFR2/PI3K/Akt signaling and inhibit microglia/macrophages TLR4/NF-κB-dependent neuroinflammation to improve functional recovery after spinal cord injury

(2017) Jian Chen et al.   Cell Death & Disease

Sam68 promotes Schwann cell proliferation by enhancing the PI3K/Akt pathway and acts on regeneration after sciatic nerve crush

(2016) Weijie Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Schwann cell mitochondria as key regulators in the development and maintenance of peripheral nerve axons

(2016) Daisuke Ino et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

FGF10: A multifunctional mesenchymal–epithelial signaling growth factor in development, health, and disease

(2016) Nobuyuki Itoh   CYTOKINE & GROWTH FACTOR REVIEWS

Nerve Regeneration

(2016) Tessa Gordon   HAND CLINICS

Paeoniflorin protects Schwann cells against high glucose induced oxidative injury by activating Nrf2/ARE pathway and inhibiting apoptosis

(2016) Xinwei Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS

(2016) E. Domenech-Estevez et al.   JOURNAL OF NEUROSCIENCE

The repair Schwann cell and its function in regenerating nerves

(2016) K. R. Jessen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Intranasal Insulin Prevents Anesthesia-Induced Spatial Learning and Memory Deficit in Mice

(2016) Yongli Zhang et al.   Scientific Reports

Neuron-derived FGF10 ameliorates cerebral ischemia injury via inhibiting NF-κB-dependent neuroinflammation and activating PI3K/Akt survival signaling pathway in mice

(2016) Yong-Hua Li et al.   Scientific Reports

Netrin-1 induces the migration of Schwann cells via p38 MAPK and PI3K-Akt signaling pathway mediated by the UNC5B receptor

(2015) Jianwei Lv et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fibroblast growth factor 10 protects neuron against oxygen–glucose deprivation injury through inducing heme oxygenase-1

(2015) Yong-Hua Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Schwann Cells: Development and Role in Nerve Repair

(2015) Kristján R. Jessen et al.   Cold Spring Harbor Perspectives in Biology

Peroxisome proliferator-activated receptorβ/δ activation is essential for modulating p-Foxo1/Foxo1 status in functional insulin-positive cell differentiation

(2015) L Li et al.   Cell Death & Disease

The Fibroblast Growth Factor signaling pathway

(2015) David M. Ornitz et al.   Wiley Interdisciplinary Reviews-Developmental Biology

FGF10 promotes regional foetal cardiomyocyte proliferation and adult cardiomyocyte cell-cycle re-entry

(2014) Francesca Rochais et al.   CARDIOVASCULAR RESEARCH

Inhibition of glycogen synthase kinase 3 ameliorates liver ischemia/reperfusion injury via an energy-dependent mitochondrial mechanism

(2014) Hailong Fu et al.   JOURNAL OF HEPATOLOGY

Nerve growth factor improves functional recovery by inhibiting endoplasmic reticulum stress-induced neuronal apoptosis in rats with spinal cord injury

(2014) Hongyu Zhang et al.   Journal of Translational Medicine

Naphthazarin protects against glutamate-induced neuronal death via activation of the Nrf2/ARE pathway

(2013) Tae Gen Son et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fibroblast growth factor receptors, developmental corruption and malignant disease

(2013) F. C. Kelleher et al.   CARCINOGENESIS

Oxidative stress response elicited by mitochondrial dysfunction: Implication in the pathophysiology of aging

(2013) Chih-Hao Wang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Regulation of Nrf2—an update

(2013) Suryakant K. Niture et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sustained bFGF-Release Tubes for Peripheral Nerve Regeneration

(2013) Takehiko Takagi et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Nrf2 Protein Up-regulates Antiapoptotic Protein Bcl-2 and Prevents Cellular Apoptosis

(2012) Suryakant K. Niture et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

bFGF inhibits ER stress induced by ischemic oxidative injury via activation of the PI3K/Akt and ERK1/2 pathways

(2012) Zhouguang Wang et al.   TOXICOLOGY LETTERS

Carboxymethylated chitosan stimulates proliferation of Schwann cells in vitro via the activation of the ERK and Akt signaling pathways

(2011) Bin He et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Synergistic effects of NGF, CNTF and GDNF on functional recovery following sciatic nerve injury in rats

(2010) J Chen et al.   Advances in Medical Sciences

INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis

(2010) S K Niture et al.   CELL DEATH AND DIFFERENTIATION

Nerve Growth Factor Induces Axonal Filopodia through Localized Microdomains of Phosphoinositide 3-Kinase Activity That Drive the Formation of Cytoskeletal Precursors to Filopodia

(2010) A. Ketschek et al.   JOURNAL OF NEUROSCIENCE

The effect of collagen-binding NGF-β on the promotion of sciatic nerve regeneration in a rat sciatic nerve crush injury model

(2009) Wenjie Sun et al.   BIOMATERIALS

Mitochondrial reticulum network dynamics in relation to oxidative stress, redox regulation, and hypoxia

(2009) Petr Ježek et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

ROLE OF CHRONIC SCHWANN CELL DENERVATION IN POOR FUNCTIONAL RECOVERY AFTER NERVE INJURIES AND EXPERIMENTAL STRATEGIES TO COMBAT IT

(2009) Olawale A.R. Sulaiman et al.   NEUROSURGERY

Molecular mechanisms of inherited demyelinating neuropathies

(2008) Steven S. Scherer et al.   GLIA