Memory and Learning Deficits Are Associated With Ca2+ Dyshomeostasis in Normal Aging

Evidence of a Role for the TRPC Subfamily in Mediating Oxidative Stress in Parkinson’s Disease

(2020) Daniele Maria-Ferreira et al.   Frontiers in Physiology

Genetic conversion of proliferative astroglia into neurons after cerebral ischemia: a new therapeutic tool for the aged brain?

(2019) Aurel Popa-Wagner et al.   GeroScience

Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging

(2019) Stefano Tarantini et al.   GeroScience

Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice

(2019) Gabor A. Fulop et al.   GeroScience

Redox Signaling in Neurotransmission and Cognition During Aging

(2018) Ashok Kumar et al.   ANTIOXIDANTS & REDOX SIGNALING

Updated guide for the management of malignant hyperthermia

(2018) Sheila Riazi et al.   Canadian Journal of Anesthesia-Journal canadien d anesthesie

Enhancing Endogenous Nitric Oxide by Whole Body Periodic Acceleration Elicits Neuroprotective Effects in Dystrophic Neurons

(2018) Jose R. Lopez et al.   MOLECULAR NEUROBIOLOGY

Regulatory role of calpain in neuronal death

(2018) Kun Xiong et al.   Neural Regeneration Research

Oxidative stress, aging, and diseases

(2018) Ilaria Liguori et al.   Clinical Interventions in Aging

Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice

(2018) Sreemathi Logan et al.   GeroScience

Calcium dysregulation and Cdk5-ATM pathway involved in a mouse model of fragile X-associated tremor/ataxia syndrome

(2017) Gaëlle Robin et al.   HUMAN MOLECULAR GENETICS

Men and mice: Relating their ages

(2016) Sulagna Dutta et al.   LIFE SCIENCES

Dysregulation of Intracellular Ca2+ in Dystrophic Cortical and Hippocampal Neurons

(2016) José R. Lopez et al.   MOLECULAR NEUROBIOLOGY

Episodic memory in normal aging and Alzheimer disease: Insights from imaging and behavioral studies

(2015) D. Tromp et al.   AGEING RESEARCH REVIEWS

Dantrolene, A Treatment for Alzheimer Disease?

(2015) Li Liang et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels

(2015) T Maier et al.   BRITISH JOURNAL OF PHARMACOLOGY

Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus

(2015) J. C. Gant et al.   JOURNAL OF NEUROSCIENCE

Contribution of Ca2+ Release Channels to Hippocampal Synaptic Plasticity and Spatial Memory: Potential Redox Modulation

(2014) Andrea C. Paula-Lima et al.   ANTIOXIDANTS & REDOX SIGNALING

Neuronal calcium signaling: function and dysfunction

(2014) Marisa Brini et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Differential rescue of spatial memory deficits in aged rats by L-type voltage-dependent calcium channel and ryanodine receptor antagonism

(2014) S.C. Hopp et al.   NEUROSCIENCE

Physiological Function and Characterization of TRPCs in Neurons

(2014) Yuyang Sun et al.   Cells

Targeting TRPs in Neurodegenerative Disorders

(2013) Yoshinori Takada et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

TRPC Channels and their Implications for Neurological Diseases

(2012) Senthil Selvaraj et al.   CNS & Neurological Disorders-Drug Targets

Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia

(2012) José M. Eltit et al.   FASEB JOURNAL

Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice

(2012) Jun Peng et al.   NEUROSCIENCE LETTERS

Expression levels of TRPC1 and TRPC6 ion channels are reciprocally altered in aging rat aorta: implications for age-related vasospastic disorders

(2010) Yasemin Erac et al.   AGE

RyR1-mediated Ca2+Leak and Ca2+Entry Determine Resting Intracellular Ca2+in Skeletal Myotubes

(2010) José M. Eltit et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Sensitive Calcium Stores Underlie Enhanced After Hyperpolarization of Aged Neurons: Role for Ryanodine Receptor Mediated Calcium Signaling

(2010) Karthik Bodhinathan et al.   JOURNAL OF NEUROPHYSIOLOGY

Ca2+spark-dependent and -independent sarcoplasmic reticulum Ca2+leak in normal and failing rabbit ventricular myocytes

(2010) Aleksey V. Zima et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oral apolipoprotein A-I mimetic peptide improves cognitive function and reduces amyloid burden in a mouse model of Alzheimer's disease

(2009) Shaila P. Handattu et al.   NEUROBIOLOGY OF DISEASE

Modeling spatial learning in rats based on Morris water maze experiments

(2009) Christel Faes et al.   PHARMACEUTICAL STATISTICS

Calcium signaling and neurodegenerative diseases

(2009) Ilya Bezprozvanny   TRENDS IN MOLECULAR MEDICINE

Crosstalk Between Calcium and Redox Signaling: From Molecular Mechanisms to Health Implications

(2008) Cecilia Hidalgo et al.   ANTIOXIDANTS & REDOX SIGNALING

Increased intraneuronal resting [Ca2+] in adult Alzheimer’s disease mice

(2008) José R. Lopez et al.   JOURNAL OF NEUROCHEMISTRY

Enhanced Excitation-Coupled Calcium Entry in Myotubes Expressing Malignant Hyperthermia Mutation R163C Is Attenuated by Dantrolene

(2008) G. Cherednichenko et al.   MOLECULAR PHARMACOLOGY

Impaired calcium homeostasis in aged hippocampal neurons

(2008) Parvana Hajieva et al.   NEUROSCIENCE LETTERS

The efficacy of dantrolene sodium in controlling exertional rhabdomyolysis in the Thoroughbred racehorse

(2007) J. G. T. Edwards et al.   EQUINE VETERINARY JOURNAL