Internally Responsive Nanomaterials for Activatable Multimodal Imaging of Cancer

Protein@Inorganic Nanodumpling System for High-Loading Protein Delivery with Activatable Fluorescence and Magnetic Resonance Bimodal Imaging Capabilities

(2020) Xiaohua Zhu et al.   ACS Nano

A sensitive and specific nanosensor for monitoring extracellular potassium levels in the brain

(2020) Jianan Liu et al.   Nature Nanotechnology

Magnetic Semiconductor Gd-Doping CuS Nanoparticles as Activatable Nanoprobes for Bimodal Imaging and Targeted Photothermal Therapy of Gastric Tumors

(2019) Hua Shi et al.   NANO LETTERS

A Bimodal Fluorescence-Magnetic Resonance Contrast Agent for Apoptosis Imaging

(2019) Hao Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

pH-Activatable Tumor-Targeting Gold Nanoprobe for Near-Infrared Fluorescence/CT dual-Modal Imaging In Vivo

(2019) Yao Tang et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

A Photoacoustic Probe for the Imaging of Tumor Apoptosis by Caspase-Mediated Macrocyclization and Self-Assembly

(2019) Yuqi Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hyaluronic Acid-Based Activatable Nanomaterials for Stimuli-Responsive Imaging and Therapeutics: Beyond CD44-Mediated Drug Delivery

(2019) Ki Young Choi et al.   ADVANCED MATERIALS

An Extendable Star-Like Nanoplatform for Functional and Anatomical Imaging-Guided Photothermal Oncotherapy

(2019) Xuexiang Han et al.   ACS Nano

Coordinatively Unsaturated Fe3+ Based Activable Probes for Enhanced MRI and Therapy of Tumors

(2019) Peisen Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Activatable NIR Fluorescence/MRI Bimodal Probes for in Vivo Imaging by Enzyme-Mediated Fluorogenic Reaction and Self-Assembly

(2019) Runqi Yan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Versatile Octapod-Shaped Hollow Porous Manganese(II) Oxide Nanoplatform for Real-Time Visualization of Cargo Delivery

(2019) Ruixue Wei et al.   NANO LETTERS

Activatable Hybrid Polyphosphazene-AuNP Nanoprobe for ROS Detection by Bimodal PA/CT Imaging

(2019) Mathilde Bouché et al.   ACS Applied Materials & Interfaces

Tumor Microenvironment Responsive Shape-Reversal Self-Targeting Virus-Inspired Nanodrug for Imaging-Guided Near-Infrared-II Photothermal Chemotherapy

(2019) Yang Li et al.   ACS Nano

Oxygen-supplementing mesoporous polydopamine nanosponges with WS2 QDs-embedded for CT/MSOT/MR imaging and thermoradiotherapy of hypoxic cancer

(2019) Yidan Wang et al.   BIOMATERIALS

Biodegradation-Mediated Enzymatic Activity-Tunable Molybdenum Oxide Nanourchins for Tumor-Specific Cascade Catalytic Therapy

(2019) Xi Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tandem Molecular Self-Assembly in Liver Cancer Cells

(2018) Jie Zhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multimodality Imaging Agents with PET as the Fundamental Pillar

(2018) Dalong Ni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multifunctional Nanoflowers for Simultaneous Multimodal Imaging and High-Sensitivity Chemo-Photothermal Treatment

(2018) Xunan Jing et al.   BIOCONJUGATE CHEMISTRY

Oxygen-boosted immunogenic photodynamic therapy with gold nanocages@manganese dioxide to inhibit tumor growth and metastases

(2018) Ruijing Liang et al.   BIOMATERIALS

Advances in transformable drug delivery systems

(2018) Quanyin Hu et al.   BIOMATERIALS

Thrombin-activatable fluorescent peptide incorporated gold nanoparticles for dual optical/computed tomography thrombus imaging

(2018) Sung-Pil Kwon et al.   BIOMATERIALS

Synthesis of Hollow Biomineralized CaCO3–Polydopamine Nanoparticles for Multimodal Imaging-Guided Cancer Photodynamic Therapy with Reduced Skin Photosensitivity

(2018) Ziliang Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Scavenging of reactive oxygen and nitrogen species with nanomaterials

(2018) Carolina A. Ferreira et al.   Nano Research

Stimuli-responsive nanotherapeutics for precision drug delivery and cancer therapy

(2018) Yiting Qiao et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Versatile in situ synthesis of MnO2 nanolayers on upconversion nanoparticles and their application in activatable fluorescence and MRI imaging

(2018) Yuan Wu et al.   Chemical Science

MRI/Fluorescence bimodal amplification system for cellular GSH detection and tumor cell imaging based on manganese dioxide nanosheet

(2018) Dandan Yuan et al.   Scientific Reports

Stimuli-Responsive Nanomedicines for Overcoming Cancer Multidrug Resistance

(2018) Lei Zhou et al.   Theranostics

Gadolinium Metallofullerene-Polypyrrole Nanoparticles for Activatable Dual-Modal Imaging-Guided Photothermal Therapy

(2018) Sheng Wang et al.   ACS Applied Materials & Interfaces

Honeycomb-Satellite Structured pH/H2O2-Responsive Degradable Nanoplatform for Efficient Photodynamic Therapy and Multimodal Imaging

(2018) Qianqian Sun et al.   ACS Applied Materials & Interfaces

Porous gold nanocluster-decorated manganese monoxide nanocomposites for microenvironment-activatable MR/photoacoustic/CT tumor imaging

(2018) Yu Liu et al.   Nanoscale

Advances in redox-responsive drug delivery systems of tumor microenvironment

(2018) Xiaoshuang Guo et al.   JOURNAL OF NANOBIOTECHNOLOGY

Core–Satellite Nanomedicines for in Vivo Real-Time Monitoring of Enzyme-Activatable Drug Release by Fluorescence and Photoacoustic Dual-Modal Imaging

(2018) Xianlei Li et al.   ACS Nano

External stimulus responsive inorganic nanomaterials for cancer theranostics

(2018) Sheikh Mohamed M. et al.   ADVANCED DRUG DELIVERY REVIEWS

Alkaline Phosphatase-Triggered Self-Assembly of Near-Infrared Nanoparticles for the Enhanced Photoacoustic Imaging of Tumors

(2018) Chengfan Wu et al.   NANO LETTERS

Matrix-metalloproteinases as targets for controlled delivery in cancer: An analysis of upregulation and expression

(2017) Kyle J. Isaacson et al.   JOURNAL OF CONTROLLED RELEASE

Redox-Mediated Disassembly to Build Activatable Trimodal Probe for Molecular Imaging of Biothiols

(2016) Mengmeng Zheng et al.   ACS Nano

Intracellularly Acid-Switchable Multifunctional Micelles for Combinational Photo/Chemotherapy of the Drug-Resistant Tumor

(2016) Tingting Wang et al.   ACS Nano

A Smart Photosensitizer-Manganese Dioxide Nanosystem for Enhanced Photodynamic Therapy by Reducing Glutathione Levels in Cancer Cells

(2016) Huanhuan Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CaCO3 nanoparticles as an ultra-sensitive tumor-pH-responsive nanoplatform enabling real-time drug release monitoring and cancer combination therapy

(2016) Ziliang Dong et al.   BIOMATERIALS

Activatable albumin-photosensitizer nanoassemblies for triple-modal imaging and thermal-modulated photodynamic therapy of cancer

(2016) Dehong Hu et al.   BIOMATERIALS

Mechanisms and biomaterials in pH-responsive tumour targeted drug delivery: A review

(2016) Manju Kanamala et al.   BIOMATERIALS

Hybrid graphene/Au activatable theranostic agent for multimodalities imaging guided enhanced photothermal therapy

(2016) Shi Gao et al.   BIOMATERIALS

Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke

(2016) Shanyan Chen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

pH-Activatable MnO-Based Fluorescence and Magnetic Resonance Bimodal Nanoprobe for Cancer Imaging

(2016) Benedict You Wei Hsu et al.   Advanced Healthcare Materials

Bioresponsive materials

(2016) Yue Lu et al.   Nature Reviews Materials

A Smart DNAzyme-MnO2Nanosystem for Efficient Gene Silencing

(2015) Huanhuan Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanomedicines Targeting the Tumor Microenvironment

(2015) Rong Tong et al.   CANCER JOURNAL

Tumor microenvironment: Sanctuary of the devil

(2015) Lanlan Hui et al.   CANCER LETTERS

Activatable Hyaluronic Acid Nanoparticle as a Theranostic Agent for Optical/Photoacoustic Image-Guided Photothermal Therapy

(2014) Liwen Zhang et al.   ACS Nano

Stimuli-Responsive Materials for Controlled Release of Theranostic Agents

(2014) Yucai Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Break-up of Two-Dimensional MnO2Nanosheets Promotes Ultrasensitive pH-Triggered Theranostics of Cancer

(2014) Yu Chen et al.   ADVANCED MATERIALS

Stimuli-responsive cancer therapy based on nanoparticles

(2014) Jing Yu et al.   CHEMICAL COMMUNICATIONS

Activatable Fluorescence/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet–Aptamer Nanoprobe

(2014) Zilong Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multifunctional Tumor pH-Sensitive Self-Assembled Nanoparticles for Bimodal Imaging and Treatment of Resistant Heterogeneous Tumors

(2014) Daishun Ling et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multifunctional Envelope-Type Mesoporous Silica Nanoparticles for Tumor-Triggered Targeting Drug Delivery

(2013) Jing Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

Role of Glutathione in Cancer Progression and Chemoresistance

(2013) Nicola Traverso et al.   Oxidative Medicine and Cellular Longevity

Enzyme-responsive nanoparticles for drug release and diagnostics

(2012) Roberto de la Rica et al.   ADVANCED DRUG DELIVERY REVIEWS

Oxidative stress and cancer: An overview

(2012) Venus Sosa et al.   AGEING RESEARCH REVIEWS

Glutathione levels in human tumors

(2012) Michael P. Gamcsik et al.   BIOMARKERS

Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis

(2012) L. Ouyang et al.   CELL PROLIFERATION

Rationale Behind Targeting Fibroblast Activation Protein-Expressing Carcinoma-Associated Fibroblasts as a Novel Chemotherapeutic Strategy

(2012) W. N. Brennen et al.   MOLECULAR CANCER THERAPEUTICS

Therapeutic targets in cancer cell metabolism and autophagy

(2012) Heesun Cheong et al.   NATURE BIOTECHNOLOGY

Review of functional/anatomical imaging in oncology

(2012) Stephanie N. Histed et al.   NUCLEAR MEDICINE COMMUNICATIONS

A Molecular Imaging Primer: Modalities, Imaging Agents, and Applications

(2012) Michelle L. James et al.   PHYSIOLOGICAL REVIEWS

An activatable multimodal/multifunctional nanoprobe for direct imaging of intracellular drug delivery

(2011) Rajendra N. Mitra et al.   BIOMATERIALS

Multifunctional nanoparticles for multimodal imaging and theragnosis

(2011) Dong-Eun Lee et al.   CHEMICAL SOCIETY REVIEWS

Development of MRI/NIRF ‘activatable’ multimodal imaging probe based on iron oxide nanoparticles

(2011) Eui-Joon Cha et al.   JOURNAL OF CONTROLLED RELEASE

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases

(2010) E. S. Olson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduction-sensitive polymers and bioconjugates for biomedical applications

(2009) Fenghua Meng et al.   BIOMATERIALS

Theory, Practice, and Applications of Paramagnetic Relaxation Enhancement for the Characterization of Transient Low-Population States of Biological Macromolecules and Their Complexes

(2009) G. Marius Clore et al.   CHEMICAL REVIEWS

The cell cycle is a redox cycle: Linking phase-specific targets to cell fate

(2009) William C. Burhans et al.   FREE RADICAL BIOLOGY AND MEDICINE

Serine proteases

(2009) Enrico Di Cera   IUBMB LIFE

New Technologies for Human Cancer Imaging

(2008) John V. Frangioni   JOURNAL OF CLINICAL ONCOLOGY

Multimodality Molecular Imaging of Tumor Angiogenesis

(2008) W. Cai et al.   JOURNAL OF NUCLEAR MEDICINE

Imaging and cancer: A review

(2008) Leonard Fass   Molecular Oncology

Imaging in the era of molecular oncology

(2008) Ralph Weissleder et al.   NATURE

Caspases in apoptosis and beyond

(2008) J Li et al.   ONCOGENE