Cardioprotective effects of miR-34a silencing in a rat model of doxorubicin toxicity

Pterostilbene prevents hepatocyte EMT in fructose-induced liver fibrosis through suppressing miR-34a/Sirt1/p53 and TGF-β1/Smads signaling

(2019) Lin Song et al.   BRITISH JOURNAL OF PHARMACOLOGY

Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation

(2019) Yong Pan et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming

(2018) Agnes L.C. Ong et al.   AGEING RESEARCH REVIEWS

Variations of circulating cardiac biomarkers during and after anthracycline-containing chemotherapy in breast cancer patients

(2018) Pierre Frères et al.   BMC CANCER

MicroRNA-34a modulates the Notch signaling pathway in mice with congenital heart disease and its role in heart development

(2018) Kai-Hong Wu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Toxicity of Doxorubicin (Dox) to different experimental organ systems

(2018) Arivalagan Pugazhendhi et al.   LIFE SCIENCES

Doxorubicin targets multiple players: A new view of an old problem

(2018) Donato Cappetta et al.   PHARMACOLOGICAL RESEARCH

MicroRNAs in the diagnosis and prevention of drug-induced cardiotoxicity

(2018) Mikuláš Skála et al.   ARCHIVES OF TOXICOLOGY

Circulating Plasma Extracellular Vesicles from Septic Mice Induce Inflammation via MicroRNA- and TLR7-Dependent Mechanisms

(2018) Jinjin Xu et al.   JOURNAL OF IMMUNOLOGY

Plasmatic and chamber-specific modulation of cardiac microRNAs in an acute model of DOX-induced cardiotoxicity

(2018) Sonia Gioffré et al.   BIOMEDICINE & PHARMACOTHERAPY

Role of microRNAs in doxorubicin-induced cardiotoxicity: an overview of preclinical models and cancer patients

(2017) Clarissa Ruggeri et al.   HEART FAILURE REVIEWS

Inhibition of microRNA-34a ameliorates murine collagen-induced arthritis

(2017) Qiujie Dang et al.   Experimental and Therapeutic Medicine

MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis

(2017) Mariola Kurowska-Stolarska et al.   Nature Communications

Activation of miR-34a-5p/Sirt1/p66shc pathway contributes to doxorubicin-induced cardiotoxicity

(2017) Jie-Ning Zhu et al.   Scientific Reports

Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine

(2017) Chiranjib Chakraborty et al.   Molecular Therapy-Nucleic Acids

Nociceptin/orphanin FQ (N/OFQ) modulates immunopathology and airway hyperresponsiveness representing a novel target for the treatment of asthma

(2016) Shailendra R Singh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Doxorubicin-Induced Systemic Inflammation Is Driven by Upregulation of Toll-Like Receptor TLR4 and Endotoxin Leakage

(2016) Lintao Wang et al.   CANCER RESEARCH

Cardiac Fibrosis

(2016) Joshua G. Travers et al.   CIRCULATION RESEARCH

Long-term administration of ranolazine attenuates diastolic dysfunction and adverse myocardial remodeling in a model of heart failure with preserved ejection fraction

(2016) Antonella De Angelis et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

SIRT1 activation attenuates diastolic dysfunction by reducing cardiac fibrosis in a model of anthracycline cardiomyopathy

(2016) Donato Cappetta et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

MicroRNAs in Cardiovascular Disease

(2016) Temo Barwari et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

HDL and microRNA therapeutics in cardiovascular disease

(2016) Danielle L. Michell et al.   PHARMACOLOGY & THERAPEUTICS

MicroRNA-34a regulates doxorubicin-induced cardiotoxicity in rat

(2016) Elena Piegari et al.   Oncotarget

Inhibition of miR-154 Protects Against Cardiac Dysfunction and Fibrosis in a Mouse Model of Pressure Overload

(2016) Bianca C. Bernardo et al.   Scientific Reports

The role of sirtuins in cardiac disease

(2015) Shouji Matsushima et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The concomitant management of cancer therapy and cardiac therapy

(2015) Emanuela Salvatorelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

MiR-125b is Critical for Fibroblast-to-Myofibroblast Transition and Cardiac Fibrosis

(2015) Varun Nagpal et al.   CIRCULATION

MicroRNA-34a Plays a Key Role in Cardiac Repair and Regeneration Following Myocardial InfarctionNovelty and Significance

(2015) Yanfei Yang et al.   CIRCULATION RESEARCH

SIRT1 activation rescues doxorubicin-induced loss of functional competence of human cardiac progenitor cells

(2015) Antonella De Angelis et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Cardiotoxicity of anticancer treatments

(2015) Michael S. Ewer et al.   Nature Reviews Cardiology

Diastolic Dysfunction Following Anthracycline-Based Chemotherapy in Breast Cancer Patients: Incidence and Predictors

(2015) J. M. Serrano et al.   ONCOLOGIST

Myocardial MiR-30 downregulation triggered by doxorubicin drives alterations in β-adrenergic signaling and enhances apoptosis

(2015) L Roca-Alonso et al.   Cell Death & Disease

Neoadjuvant Chemotherapy in Breast Cancer Patients Induces miR-34a and miR-122 Expression

(2014) Pierre Frères et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Silencing of miR-34a Attenuates Cardiac Dysfunction in a Setting of Moderate, but Not Severe, Hypertrophic Cardiomyopathy

(2014) Bianca C. Bernardo et al.   PLoS One

Early biomarkers of doxorubicin-induced heart injury in a mouse model

(2014) Varsha G. Desai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The p53/miR-34 axis in development and disease

(2014) M. Rokavec et al.   Journal of Molecular Cell Biology

Doxorubicin induces senescence and impairs function of human cardiac progenitor cells

(2013) Elena Piegari et al.   BASIC RESEARCH IN CARDIOLOGY

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

(2013) Anu Kauppinen et al.   CELLULAR SIGNALLING

MicroRNA-34a regulates cardiac ageing and function

(2013) Reinier A. Boon et al.   NATURE

Transcriptional activation of microRNA-34a by NF-kappa B in human esophageal cancer cells

(2012) Juan Li et al.   BMC MOLECULAR BIOLOGY

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles

(2012) Eva van Rooij et al.   NATURE REVIEWS DRUG DISCOVERY

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

(2012) B. C. Bernardo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic Inhibition of miR-208a Improves Cardiac Function and Survival During Heart Failure

(2011) Rusty L. Montgomery et al.   CIRCULATION

Inhibition of miR-15 Protects Against Cardiac Ischemic Injury

(2011) Thomas G. Hullinger et al.   CIRCULATION RESEARCH

p53 deacetylation by SIRT1 decreases during protein kinase CKII downregulation-mediated cellular senescence

(2011) Seok Young Jang et al.   FEBS LETTERS

Effect of microRNA-34a in cell cycle, differentiation, and apoptosis: A review

(2011) Fei Chen et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Resveratrol Inhibits Renal Fibrosis in the Obstructed Kidney

(2010) Jinhua Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Anthracycline-Induced Cardiomyopathy

(2010) Daniela Cardinale et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Anthracycline Cardiomyopathy Is Mediated by Depletion of the Cardiac Stem Cell Pool and Is Rescued by Restoration of Progenitor Cell Function

(2009) Antonella De Angelis et al.   CIRCULATION