Doxorubicin induces senescence and impairs function of human cardiac progenitor cells

Pressure overload leads to an increase of cardiac resident stem cells

(2012) Stefan Rupp et al.   BASIC RESEARCH IN CARDIOLOGY

Cardiac progenitors derived from reprogrammed mesenchymal stem cells contribute to angiomyogenic repair of the infarcted heart

(2012) Stephanie Buccini et al.   BASIC RESEARCH IN CARDIOLOGY

Role of HMGB1 in doxorubicin-induced myocardial apoptosis and its regulation pathway

(2012) Yongwei Yao et al.   BASIC RESEARCH IN CARDIOLOGY

Inhibition of AMP-activated Protein Kinase α (AMPKα) by Doxorubicin Accentuates Genotoxic Stress and Cell Death in Mouse Embryonic Fibroblasts and Cardiomyocytes

(2012) Shaobin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of Age and Heart Failure on Human Cardiac Stem Cell Function

(2011) Daniela Cesselli et al.   AMERICAN JOURNAL OF PATHOLOGY

Intracoronary administration of cardiac stem cells in mice: a new, improved technique for cell therapy in murine models

(2011) Qianhong Li et al.   BASIC RESEARCH IN CARDIOLOGY

Stem cell-based therapies in ischemic heart diseases: a focus on aspects of microcirculation and inflammation

(2011) Junxi Wu et al.   BASIC RESEARCH IN CARDIOLOGY

Cardiac cell therapy: where we've been, where we are, and where we should be headed

(2011) K. Malliaras et al.   BRITISH MEDICAL BULLETIN

Cardiovascular Disease

(2011) Ming Hui Chen et al.   CIRCULATION RESEARCH

Insulin-Like Growth Factor-1 Receptor Identifies a Pool of Human Cardiac Stem Cells With Superior Therapeutic Potential for Myocardial Regeneration

(2011) Domenico D'Amario et al.   CIRCULATION RESEARCH

SCIPIO brings new momentum to cardiac cell therapy

(2011) Gerd Heusch   LANCET

Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial

(2011) Roberto Bolli et al.   LANCET

Juvenile Exposure to Anthracyclines Impairs Cardiac Progenitor Cell Function and Vascularization Resulting in Greater Susceptibility to Stress-Induced Myocardial Injury in Adult Mice

(2010) Chengqun Huang et al.   CIRCULATION

Myocyte Turnover in the Aging Human Heart

(2010) Jan Kajstura et al.   CIRCULATION RESEARCH

p38 MAPK and JNK Antagonistically Control Senescence and Cytoplasmic p16INK4A Expression in Doxorubicin-Treated Endothelial Progenitor Cells

(2010) Paolo Spallarossa et al.   PLoS One

Long-Term Survivors of Childhood Cancers in the United States

(2009) A. B. Mariotto et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Anthracycline Cardiomyopathy Is Mediated by Depletion of the Cardiac Stem Cell Pool and Is Rescued by Restoration of Progenitor Cell Function

(2009) Antonella De Angelis et al.   CIRCULATION

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

HSP27 regulates p53 transcriptional activity in doxorubicin-treated fibroblasts and cardiac H9c2 cells: p21 upregulation and G2/M phase cell cycle arrest

(2008) C. D. Venkatakrishnan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Activation of Cardiac Progenitor Cells Reverses the Failing Heart Senescent Phenotype and Prolongs Lifespan

(2008) Arantxa Gonzalez et al.   CIRCULATION RESEARCH

Anthracycline Cardiotoxicity: From Bench to Bedside

(2008) Luca Gianni et al.   JOURNAL OF CLINICAL ONCOLOGY