Cyclosporine A Treatment Abrogates Ischemia-Induced Neuronal Cell Death by Preserving Mitochondrial Integrity through Upregulation of the Parkinson's Disease-Associated Protein DJ-1

DJ-1-dependent protective activity of DJ-1-binding compound no. 23 against neuronal cell death in MPTP-treated mouse model of Parkinson's disease

(2015) Kazuko Takahashi-Niki et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Kainic Acid-Induced Golgi Complex Fragmentation/Dispersal Shifts the Proteolysis of Reelin in Primary Rat Neuronal Cells: An In Vitro Model of Early Stage Epilepsy

(2015) Yuji Kaneko et al.   MOLECULAR NEUROBIOLOGY

The role of DJ-1 in the oxidative stress cell death cascade after stroke

(2014) Naoki Tajiri et al.   Neural Regeneration Research

DJ-1 protects against cell death following acute cardiac ischemia–reperfusion injury

(2014) R K Dongworth et al.   Cell Death & Disease

DJ-1 cooperates with PYCR1 in cell protection against oxidative stress

(2013) Tatsuki Yasuda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxygen-Glucose-Deprived Rat Primary Neural Cells Exhibit DJ-1 Translocation into Healthy Mitochondria: A Potent Stroke Therapeutic Target

(2013) Yuji Kaneko et al.   CNS Neuroscience & Therapeutics

DJ-1 ameliorates ischemic cell death in vitro possibly via mitochondrial pathway

(2013) Yuji Kaneko et al.   NEUROBIOLOGY OF DISEASE

Neuroprotective Function of DJ-1 in Parkinson’s Disease

(2013) Hiroyoshi Ariga et al.   Oxidative Medicine and Cellular Longevity

Axis of ageing: telomeres, p53 and mitochondria

(2012) Ergün Sahin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Loss of DJ-1 Does Not Affect Mitochondrial Respiration but Increases ROS Production and Mitochondrial Permeability Transition Pore Opening

(2012) Emilie Giaime et al.   PLoS One

Making heads or tails of phospholipids in mitochondria

(2011) Christof Osman et al.   JOURNAL OF CELL BIOLOGY

Identification of an artificial peptide motif that binds and stabilizes reduced human DJ-1

(2011) Lakshmanane Premkumar et al.   JOURNAL OF STRUCTURAL BIOLOGY

The Potent Antimalarial Peptide Cyclosporin A Induces the Aggregation and Permeabilization of Sphingomyelin-Rich Membranes

(2011) Slim Azouzi et al.   LANGMUIR

Cyclosporine-A as a neuroprotective agent against stroke: Its translation from laboratory research to clinical application

(2011) Mohamed M. Osman et al.   NEUROPEPTIDES

A Review of Laboratory and Clinical Data Supporting the Safety and Efficacy of Cyclosporin A in Traumatic Brain Injury

(2011) Dzenan Lulic et al.   NEUROSURGERY

Redox regulation of mitochondrial fission, protein misfolding, synaptic damage, and neuronal cell death: potential implications for Alzheimer’s and Parkinson’s diseases

(2010) Tomohiro Nakamura et al.   APOPTOSIS

Expression of the Parkinson's Disease-Related Protein DJ-1 during Neural Stem Cell Proliferation

(2010) Hui Yan et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network

(2010) Atsushi Tanaka   FEBS LETTERS

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

(2010) Jaime N. Guzman et al.   NATURE

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Reduced Basal Autophagy and Impaired Mitochondrial Dynamics Due to Loss of Parkinson's Disease-Associated Protein DJ-1

(2010) Guido Krebiehl et al.   PLoS One

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Lysosomal Iron Mobilization and Induction of the Mitochondrial Permeability Transition in Acetaminophen-Induced Toxicity to Mouse Hepatocytes

(2010) Kazuyoshi Kon et al.   TOXICOLOGICAL SCIENCES

Therapeutic targets and limits of minocycline neuroprotection in experimental ischemic stroke

(2009) Noriyuki Matsukawa et al.   BMC NEUROSCIENCE

What is the mitochondrial permeability transition pore?

(2009) Andrew P. Halestrap   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Increased intranuclear matrix metalloproteinase activity in neurons interferes with oxidative DNA repair in focal cerebral ischemia

(2009) Yi Yang et al.   JOURNAL OF NEUROCHEMISTRY

Role of Axonal Transport in Neurodegenerative Diseases

(2008) Kurt J. De Vos et al.   Annual Review of Neuroscience

Molecular Basis for the Structural Instability of Human DJ-1 Induced by the L166P Mutation Associated with Parkinson’s Disease†

(2008) Peter C. Anderson et al.   BIOCHEMISTRY

DJ-1, a causative gene product of a familial form of Parkinson's disease, is secreted through microdomains

(2008) Yumi Tsuboi et al.   FEBS LETTERS

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Mitochondria Modulate Ca2+-Dependent Glutamate Release from Rat Cortical Astrocytes

(2008) R. C. Reyes et al.   JOURNAL OF NEUROSCIENCE

Dosing and safety of cyclosporine in patients with severe brain injury

(2008) Jimmi Hatton et al.   JOURNAL OF NEUROSURGERY

Regulation of glutathione synthesis

(2008) Shelly C. Lu   MOLECULAR ASPECTS OF MEDICINE

A new penumbra: transitioning from injury into repair after stroke

(2008) Eng H Lo   NATURE MEDICINE

Glucose sensing by MondoA:Mlx complexes: A role for hexokinases and direct regulation of thioredoxin-interacting protein expression

(2008) C. A. Stoltzman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA