A Review of Laboratory and Clinical Data Supporting the Safety and Efficacy of Cyclosporin A in Traumatic Brain Injury

Neuroprotective Effect of Bax-Inhibiting Peptide on Neonatal Brain Injury

(2010) Xiaoyang Wang et al.   STROKE

Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation

(2009) Sylvanie Malouitre et al.   BIOCHEMICAL JOURNAL

Quantitative analyses of matrix metalloproteinase activity after traumatic brain injury in adult rats

(2009) Takuro Hayashi et al.   BRAIN RESEARCH

Severity of controlled cortical impact traumatic brain injury in rats and mice dictates degree of behavioral deficits

(2009) Seongjin Yu et al.   BRAIN RESEARCH

Effect of FK506 and cyclosporine A on the expression of BDNF, tyrosine kinase B and p75 neurotrophin receptors in astrocytes exposed to simulated ischemia in vitro

(2009) Bozena Gabryel et al.   CELL BIOLOGY INTERNATIONAL

Developmental Shift of Cyclophilin D Contribution to Hypoxic-Ischemic Brain Injury

(2009) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Safety and Tolerability of Cyclosporin A in Severe Traumatic Brain Injury Patients: Results from a Prospective Randomized Trial

(2009) Anna Teresa Mazzeo et al.   JOURNAL OF NEUROTRAUMA

Remodeling of the Corticospinal Innervation and Spontaneous Behavioral Recovery After Ischemic Stroke in Adult Mice

(2009) Zhongwu Liu et al.   STROKE

Preemptive Craniectomy With Craniotomy: What Role in the Management of Severe Traumatic Brain Injury?

(2009) Gabrielle M. Paci et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Repairing the human brain after stroke: I. Mechanisms of spontaneous recovery

(2008) Steven C. Cramer   ANNALS OF NEUROLOGY

Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury*

(2008) Judith Marcoux et al.   CRITICAL CARE MEDICINE

Traumatic brain injury causes a long-lasting calcium (Ca2+)-plateau of elevated intracellular Ca levels and altered Ca2+homeostatic mechanisms in hippocampal neurons surviving brain injury

(2008) David A. Sun et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Moderate and severe traumatic brain injury induce early overexpression of systemic and brain gelatinases

(2008) Anna Vilalta et al.   INTENSIVE CARE MEDICINE

Comparative Neuroprotective Effects of Cyclosporin a and NIM811, a Nonimmunosuppressive Cyclosporin a Analog, following Traumatic Brain Injury

(2008) Lamin Han Mbye et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Trauma-Induced Cell Swelling in Cultured Astrocytes

(2008) Arumugam R. Jayakumar et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Dosing and safety of cyclosporine in patients with severe brain injury

(2008) Jimmi Hatton et al.   JOURNAL OF NEUROSURGERY

Moderate and severe traumatic brain injury in adults

(2008) Andrew IR Maas et al.   LANCET NEUROLOGY

Multifunctional drugs for head injury

(2008) Robert Vink et al.   Neurotherapeutics

Attenuation of acute mitochondrial dysfunction after traumatic brain injury in mice by NIM811, a non-immunosuppressive cyclosporin A analog

(2007) L.H. Mbye et al.   EXPERIMENTAL NEUROLOGY

Immunosuppression after traumatic or ischemic CNS damage: It is neuroprotective and illuminates the role of microglial cells

(2007) Nils P. Hailer   PROGRESS IN NEUROBIOLOGY