Region and Cell Type Distribution of TCF4 in the Postnatal Mouse Brain

A myelin-related transcriptomic profile is shared by Pitt–Hopkins syndrome models and human autism spectrum disorder

(2020) BaDoi N. Phan et al.   NATURE NEUROSCIENCE

Disruption of TCF4 regulatory networks leads to abnormal cortical development and mental disabilities

(2019) Hong Li et al.   MOLECULAR PSYCHIATRY

Diagnosis and management in Pitt-Hopkins syndrome: First international consensus statement

(2019) Marcella Zollino et al.   CLINICAL GENETICS

Therapeutic AAV Gene Transfer to the Nervous System: A Clinical Reality

(2019) Eloise Hudry et al.   NEURON

Transcription Factor 4 Safeguards Hippocampal Dentate Gyrus Development by Regulating Neural Progenitor Migration

(2019) Yafei Wang et al.   CEREBRAL CORTEX

Disease-causing variants in TCF4 are a frequent cause of intellectual disability: lessons from large-scale sequencing approaches in diagnosis

(2018) Laura Mary et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Building a schizophrenia genetic network: Transcription Factor 4 regulates genes involved in neuronal development and schizophrenia risk

(2018) Hanzhang Xia et al.   HUMAN MOLECULAR GENETICS

Pitt-Hopkins Syndrome: A Review of Current Literature, Clinical Approach, and 23-Patient Case Series

(2018) Kimberly Goodspeed et al.   JOURNAL OF CHILD NEUROLOGY

Genetic identification of brain cell types underlying schizophrenia

(2018) Nathan G. Skene et al.   NATURE GENETICS

Analysis of the expression pattern of the schizophrenia-risk and intellectual disability gene TCF4 in the developing and adult brain suggests a role in development and plasticity of cortical and hippocampal neurons

(2018) Matthias Jung et al.   Molecular Autism

The integrated landscape of causal genes and pathways in schizophrenia

(2018) Changguo Ma et al.   Translational Psychiatry

Gene therapy for neurological disorders: progress and prospects

(2018) Benjamin E. Deverman et al.   NATURE REVIEWS DRUG DISCOVERY

Diversity of Interneurons in the Dorsal Striatum Revealed by Single-Cell RNA Sequencing and PatchSeq

(2018) Ana B. Muñoz-Manchado et al.   Cell Reports

Impairment of different protein domains causes variable clinical presentation within Pitt-Hopkins syndrome and suggests intragenic molecular syndromology of TCF4

(2017) Maria Francesca Bedeschi et al.   European Journal of Medical Genetics

Common pathophysiology in multiple mouse models of Pitt-Hopkins syndrome

(2017) Courtney Thaxton et al.   JOURNAL OF NEUROSCIENCE

Knockdown of the schizophrenia susceptibility gene TCF4 alters gene expression and proliferation of progenitor cells from the developing human neocortex

(2017) Matthew J. Hill et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Hippocampal GABAergic Inhibitory Interneurons

(2017) Kenneth A. Pelkey et al.   PHYSIOLOGICAL REVIEWS

The Psychiatric Risk Gene Transcription Factor 4 (TCF4) Regulates Neurodevelopmental Pathways Associated With Schizophrenia, Autism, and Intellectual Disability

(2017) Marc P Forrest et al.   SCHIZOPHRENIA BULLETIN

The Role of Interneurons in Autism and Tourette Syndrome

(2017) Maximiliano Rapanelli et al.   TRENDS IN NEUROSCIENCES

Improved MECP2 Gene Therapy Extends the Survival of MeCP2-Null Mice without Apparent Toxicity after Intracisternal Delivery

(2017) Sarah E. Sinnett et al.   Molecular Therapy-Methods & Clinical Development

Partial deletion of TCF4 in three generation family with non-syndromic intellectual disability, without features of Pitt-Hopkins syndrome

(2016) Mira Kharbanda et al.   European Journal of Medical Genetics

Principles of Synaptic Organization of GABAergic Interneurons in the Striatum

(2016) Christoph Straub et al.   NEURON

Psychiatric Risk Gene Transcription Factor 4 Regulates Intrinsic Excitability of Prefrontal Neurons via Repression of SCN10a and KCNQ1

(2016) Matthew D. Rannals et al.   NEURON

Complex translocation disrupting TCF4 and altering TCF4 isoform expression segregates as mild autosomal dominant intellectual disability

(2016) Valerie Maduro et al.   Orphanet Journal of Rare Diseases

Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function

(2016) Andrew J. Kennedy et al.   Cell Reports

Tcf4 Controls Neuronal Migration of the Cerebral Cortex through Regulation of Bmp7

(2016) Tianda Chen et al.   Frontiers in Molecular Neuroscience

Investigation of the role ofTCF4rare sequence variants in schizophrenia

(2015) F. Buket Basmanav et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model

(2015) Sara Silva-Santos et al.   JOURNAL OF CLINICAL INVESTIGATION

Physical biology of human brain development

(2015) Silvia Budday et al.   Frontiers in Cellular Neuroscience

The role of the hippocampus in flexible cognition and social behavior

(2014) Rachael D. Rubin et al.   Frontiers in Human Neuroscience

Patches of Disorganization in the Neocortex of Children with Autism

(2014) Rich Stoner et al.   NEW ENGLAND JOURNAL OF MEDICINE

Overproduction of Upper-Layer Neurons in the Neocortex Leads to Autism-like Features in Mice

(2014) Wei-Qun Fang et al.   Cell Reports

Focal Adhesion Dynamics Are Altered in Schizophrenia

(2013) Yongjun Fan et al.   BIOLOGICAL PSYCHIATRY

Knockdown of Human TCF4 Affects Multiple Signaling Pathways Involved in Cell Survival, Epithelial to Mesenchymal Transition and Neuronal Differentiation

(2013) Marc P. Forrest et al.   PLoS One

Pitt–Hopkins syndrome-associated mutations in TCF4 lead to variable impairment of the transcription factor function ranging from hypomorphic to dominant-negative effects

(2012) Mari Sepp et al.   HUMAN MOLECULAR GENETICS

Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software

(2011) Lee Kamentsky et al.   BIOINFORMATICS

Regional Cerebellar Volumes Predict Functional Outcome in Children with Cerebellar Malformations

(2011) Marie-Eve Bolduc et al.   CEREBELLUM

Novel comprehensive diagnostic strategy in Pitt-Hopkins syndrome: Clinical score and further delineation of the TCF4 mutational spectrum

(2011) Sandra Whalen et al.   HUMAN MUTATION

RNAscope

(2011) Fay Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

From reinforcement learning models to psychiatric and neurological disorders

(2011) Tiago V Maia et al.   NATURE NEUROSCIENCE

A Resource of Cre Driver Lines for Genetic Targeting of GABAergic Neurons in Cerebral Cortex

(2011) Hiroki Taniguchi et al.   NEURON

Functional Diversity of Human Basic Helix-Loop-Helix Transcription Factor TCF4 Isoforms Generated by Alternative 5′ Exon Usage and Splicing

(2011) Mari Sepp et al.   PLoS One

Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons

(2010) Bernardo Rudy et al.   Developmental Neurobiology

The Largest Group of Superficial Neocortical GABAergic Interneurons Expresses Ionotropic Serotonin Receptors

(2010) S. Lee et al.   JOURNAL OF NEUROSCIENCE

Distinct Roles of GABAergic Interneurons in the Regulation of Striatal Output Pathways

(2010) A. H. Gittis et al.   JOURNAL OF NEUROSCIENCE

The reorganization and reactivation of hippocampal maps predict spatial memory performance

(2010) David Dupret et al.   NATURE NEUROSCIENCE

Mutational, functional, and expression studies of theTCF4gene in Pitt-Hopkins syndrome

(2009) Lo��c de Pontual et al.   HUMAN MUTATION

A Genome-Wide Screen for Spatially Restricted Expression Patterns Identifies Transcription Factors That Regulate Glial Development

(2009) H. Fu et al.   JOURNAL OF NEUROSCIENCE

Alternative Functions of Core Cell Cycle Regulators in Neuronal Migration, Neuronal Maturation, and Synaptic Plasticity

(2009) Christopher L. Frank et al.   NEURON

Decision by division: making cortical maps

(2009) Pasko Rakic et al.   TRENDS IN NEUROSCIENCES

Cerebellar Disorders in Childhood: Cognitive Problems

(2008) Maja Steinlin   CEREBELLUM

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Development of the human cerebral cortex: Boulder Committee revisited

(2008) Irina Bystron et al.   NATURE REVIEWS NEUROSCIENCE

Striatal Plasticity and Basal Ganglia Circuit Function

(2008) Anatol C. Kreitzer et al.   NEURON