p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs
Authors
Keywords
-
Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-06-17
DOI
10.1038/s41467-020-16616-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- DAPT, a γ-Secretase Inhibitor, Suppresses Tumorigenesis, and Progression of Growth Hormone-Producing Adenomas by Targeting Notch Signaling
- (2019) Jie Feng et al. Frontiers in Oncology
- Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis
- (2018) Yvette C. Wong et al. NATURE
- NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism
- (2016) Chia-Lin Chen et al. Cell Metabolism
- NuMA Phosphorylation by Aurora-A Orchestrates Spindle Orientation
- (2016) Sara Gallini et al. CURRENT BIOLOGY
- TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice
- (2016) Dinesh Babu Uthaya Kumar et al. GASTROENTEROLOGY
- Uncovering Aberrant Mutant PKA Function with Flow Cytometric FRET
- (2016) Shin-Rong Lee et al. Cell Reports
- NUMB phosphorylation destabilizes p53 and promotes self-renewal of tumor-initiating cells by a NANOG-dependent mechanism in liver cancer
- (2015) Hifzur R. Siddique et al. HEPATOLOGY
- Silencing of TBC1D15 promotes RhoA activation and membrane blebbing
- (2013) Yuko Takahara et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- The TBC1D15 Oncoprotein Controls Stem Cell Self-Renewal through Destabilization of the Numb-p53 Complex
- (2013) Douglas E. Feldman et al. PLoS One
- Ran GTPase-Activating Protein 1 Is a Therapeutic Target in Diffuse Large B-Cell Lymphoma
- (2013) Kung-Chao Chang et al. PLoS One
- Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4
- (2012) Dianne H. Dapito et al. CANCER CELL
- Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology
- (2012) Kenta Onoue et al. JOURNAL OF CELL SCIENCE
- Asymmetric cell divisions promote Notch-dependent epidermal differentiation
- (2011) Scott E. Williams et al. NATURE
- The cancer stem cell: premises, promises and challenges
- (2011) Hans Clevers NATURE MEDICINE
- Differential Effects of TBC1D15 and Mammalian Vps39 on Rab7 Activation State, Lysosomal Morphology, and Growth Factor Dependence
- (2010) Eigen R. Peralta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Flow Cytometry-Based FRET Assay to Identify and Analyse Protein-Protein Interactions in Living Cells
- (2010) Carina Banning et al. PLoS One
- Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog
- (2009) K. Machida et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PDZ Protein Canoe Regulates the Asymmetric Division of Drosophila Neuroblasts and Muscle Progenitors
- (2008) Stephan Speicher et al. CURRENT BIOLOGY
- A myristoylated pseudosubstrate peptide of PKC-ζ induces degranulation in HMC-1 cells independently of PKC-ζ activity
- (2008) Seyoung Lim et al. LIFE SCIENCES
- NUMB controls p53 tumour suppressor activity
- (2008) Ivan N. Colaluca et al. NATURE
- Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain
- (2003) H. F. Dovey et al. JOURNAL OF NEUROCHEMISTRY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started