Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway

Maltol Mitigates Thioacetamide-induced Liver Fibrosis through TGF-β1-mediated Activation of PI3K/Akt Signaling Pathway

(2019) Xiao-jie Mi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

SVIP alleviates CCl4-induced liver fibrosis via activating autophagy and protecting hepatocytes

(2019) Dan Jia et al.   Cell Death & Disease

Ginsenoside Rg3 improves cyclophosphamide-induced immunocompetence in Balb/c mice

(2019) Xiao Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

20(S)-Ginsenoside Rg3 Promotes HeLa Cell Apoptosis by Regulating Autophagy

(2019) Bian et al.   MOLECULES

20( R )-ginsenoside Rg3, a rare saponin from red ginseng, ameliorates acetaminophen-induced hepatotoxicity by suppressing PI3K/AKT pathway-mediated inflammation and apoptosis

(2018) Yan-dan Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

MicroRNA-146a-5p attenuates irradiation-induced and LPS-induced hepatic stellate cell activation and hepatocyte apoptosis through inhibition of TLR4 pathway

(2018) Yuhan Chen et al.   Cell Death & Disease

p62/ SQSTM 1: ‘Jack of all trades’ in health and cancer

(2018) Pablo Sánchez‐Martín et al.   FEBS Journal

NAADP-mediated Ca2+ signaling promotes autophagy and protects against LPS-induced liver injury

(2017) So-Young Rah et al.   FASEB JOURNAL

Liver inflammation and fibrosis

(2017) Yukinori Koyama et al.   JOURNAL OF CLINICAL INVESTIGATION

Ceanothane- and lupane-type triterpene esters from the roots of Hovenia dulcis and their antiproliferative activity on HSC-T6 cells

(2017) Kyo Bin Kang et al.   PHYTOCHEMISTRY

Interaction between autophagy and senescence is required for dihydroartemisinin to alleviate liver fibrosis

(2017) Zili Zhang et al.   Cell Death & Disease

Role of ginsenosides, the main active components of Panax ginseng , in inflammatory responses and diseases

(2017) Ji Hye Kim et al.   Journal of Ginseng Research

p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer

(2016) Koji Taniguchi et al.   FEBS LETTERS

Gut microbiome and liver diseases

(2016) Herbert Tilg et al.   GUT

Sinusoidal communication in liver fibrosis and regeneration

(2016) Giusi Marrone et al.   JOURNAL OF HEPATOLOGY

Pathobiology of liver fibrosis: a translational success story

(2015) Youngmin A Lee et al.   GUT

Hepatic inflammation and fibrosis: Functional links and key pathways

(2015) Ekihiro Seki et al.   HEPATOLOGY

20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin

(2015) Dong-Gun Kim et al.   Oncotarget

Semaphorin 3E Secreted by Damaged Hepatocytes Regulates the Sinusoidal Regeneration and Liver Fibrosis during Liver Regeneration

(2014) Tomoki Yagai et al.   AMERICAN JOURNAL OF PATHOLOGY

Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis

(2014) Ali A Mokdad et al.   BMC Medicine

Ampelopsin-induced autophagy protects breast cancer cells from apoptosis through Akt-mTOR pathway via endoplasmic reticulum stress

(2014) Yong Zhou et al.   CANCER SCIENCE

Functions of autophagy in normal and diseased liver

(2013) Mark J. Czaja et al.   Autophagy

Chronic vitamin C insufficiency aggravated thioacetamide-induced liver fibrosis in gulo-knockout mice

(2013) Jin-Hee Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

M2 Kupffer cells promote M1 Kupffer cell apoptosis: A protective mechanism against alcoholic and nonalcoholic fatty liver disease

(2013) Jinghong Wan et al.   HEPATOLOGY

Hepatic stellate cells in liver development, regeneration, and cancer

(2013) Chunyue Yin et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues

(2012) Virginia Hernández–Gea et al.   GASTROENTEROLOGY

Deactivation of Hepatic Stellate Cells During Liver Fibrosis Resolution in Mice

(2012) Juliane S. Troeger et al.   GASTROENTEROLOGY

Clinical evidence for the regression of liver fibrosis

(2012) Elizabeth L. Ellis et al.   JOURNAL OF HEPATOLOGY

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

(2012) T. Kisseleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Silybin and the liver: From basic research to clinical practice

(2011) Carmela Loguercio   WORLD JOURNAL OF GASTROENTEROLOGY

Macrophages: Master Regulators of Inflammation and Fibrosis

(2010) Thomas Wynn et al.   SEMINARS IN LIVER DISEASE

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

The regulation and function of Class III PI3Ks: novel roles for Vps34

(2008) Jonathan M. Backer   BIOCHEMICAL JOURNAL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Platelet-Derived Growth Factor Signaling Through Ephrin-B2 Regulates Hepatic Vascular Structure and Function

(2008) David Semela et al.   GASTROENTEROLOGY

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS