The Novel J-Domain Protein Mrj1 Is Required for Mitochondrial Respiration and Virulence in Cryptococcus neoformans

Inhibition of Classical and Alternative Modes of Respiration in Candida albicans Leads to Cell Wall Remodeling and Increased Macrophage Recognition

(2019) Lucian Duvenage et al.   mBio

Structural and functional analysis of the Hsp70/Hsp40 chaperone system

(2019) Qinglian Liu et al.   PROTEIN SCIENCE

Exploring and exploiting the connection between mitochondria and the virulence of human pathogenic fungi

(2018) Surbhi Verma et al.   Virulence

The Sec1/Munc18 (SM) protein Vps45 is involved in iron uptake, mitochondrial function and virulence in the pathogenic fungus Cryptococcus neoformans

(2018) Mélissa Caza et al.   PLoS Pathogens

Function, evolution, and structure of J-domain proteins

(2018) Harm H. Kampinga et al.   CELL STRESS & CHAPERONES

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Maintenance of Mitochondrial Morphology in Cryptococcus neoformans Is Critical for Stress Resistance and Virulence

(2018) Andrew L. Chang et al.   mBio

Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling

(2018) Arnab Pradhan et al.   mBio

Molecular chaperones involved in mitochondrial iron–sulfur protein biogenesis

(2017) Rafal Dutkiewicz et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

The mitochondrial ABC transporter Atm1 plays a role in iron metabolism and virulence in the human fungal pathogen Cryptococcus neoformans

(2017) Eunsoo Do et al.   MEDICAL MYCOLOGY

How Do J-Proteins Get Hsp70 to Do So Many Different Things?

(2017) Elizabeth A. Craig et al.   TRENDS IN BIOCHEMICAL SCIENCES

Heat shock protein 90 localizes to the surface and augments virulence factors of Cryptococcus neoformans

(2017) Sharanya Chatterjee et al.   PLoS Neglected Tropical Diseases

Capsule Enlargement in Cryptococcus neoformans Is Dependent on Mitochondrial Activity

(2017) Nuria Trevijano-Contador et al.   Frontiers in Microbiology

The Mitochondrial GTPase Gem1 Contributes to the Cell Wall Stress Response and Invasive Growth of Candida albicans

(2017) Barbara Koch et al.   Frontiers in Microbiology

Vital role for the J-domain protein Mdj1 in asexual development, multiple stress tolerance, and virulence of Beauveria bassiana

(2016) Jie Wang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The lysine biosynthetic enzyme Lys4 influences iron metabolism, mitochondrial function and virulence in Cryptococcus neoformans

(2016) Eunsoo Do et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mas5, a homologue of bacterial DnaJ, is indispensable for the host infection and environmental adaptation of a filamentous fungal insect pathogen

(2016) Jie Wang et al.   ENVIRONMENTAL MICROBIOLOGY

Rewiring of Signaling Networks Modulating Thermotolerance in the Human Pathogen Cryptococcus neoformans

(2016) Dong-Hoon Yang et al.   GENETICS

Inhibition of heat-shock protein 90 enhances the susceptibility to antifungals and reduces the virulence of Cryptococcus neoformans/Cryptococcus gattii species complex

(2016) Rossana de Aguiar Cordeiro et al.   MICROBIOLOGY-SGM

Exploiting mitochondria as targets for the development of new antifungals

(2016) Dongmei Li et al.   Virulence

Rewiring of Signaling Networks Modulating Thermotolerance in the Human Pathogen Cryptococcus neoformans

(2016) Dong-Hoon Yang et al.   GENETICS

The Zinc Finger Protein Mig1 Regulates Mitochondrial Function and Azole Drug Susceptibility in the Pathogenic Fungus Cryptococcus neoformans

(2016) Mélissa Caza et al.   mSphere

Fungal-specific subunits of theCandida albicansmitochondrial complex I drive diverse cell functions including cell wall synthesis

(2015) Xiaodong She et al.   CELLULAR MICROBIOLOGY

System-level impact of mitochondria on fungal virulence: to metabolism and beyond

(2015) Richard Calderone et al.   FEMS YEAST RESEARCH

Leu1 plays a role in iron metabolism and is required for virulence in Cryptococcus neoformans

(2015) Eunsoo Do et al.   FUNGAL GENETICS AND BIOLOGY

Cryptococcal Heat Shock Protein 70 Homolog Ssa1 Contributes to Pulmonary Expansion ofCryptococcus neoformansduring the Afferent Phase of the Immune Response by Promoting Macrophage M2 Polarization

(2015) Alison J. Eastman et al.   JOURNAL OF IMMUNOLOGY

MitoFates: Improved Prediction of Mitochondrial Targeting Sequences and Their Cleavage Sites

(2015) Yoshinori Fukasawa et al.   MOLECULAR & CELLULAR PROTEOMICS

The endosomal sorting complex required for transport machinery influences haem uptake and capsule elaboration inCryptococcus neoformans

(2015) Guanggan Hu et al.   MOLECULAR MICROBIOLOGY

A conserved co-chaperone is required for virulence in fungal plant pathogens

(2015) Libera Lo Presti et al.   NEW PHYTOLOGIST

A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans

(2015) Samantha D. M. Arras et al.   PLoS One

A Single Protein S-acyl Transferase Acts through Diverse Substrates to Determine Cryptococcal Morphology, Stress Tolerance, and Pathogenic Outcome

(2015) Felipe H. Santiago-Tirado et al.   PLoS Pathogens

Are mitochondria the Achilles’ heel of the Kingdom Fungi?

(2014) Laurent Chatre et al.   CURRENT OPINION IN MICROBIOLOGY

‘Division of labour’ in response to host oxidative burst drives a fatal Cryptococcus gattii outbreak

(2014) Kerstin Voelz et al.   Nature Communications

Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence Attenuation

(2014) Guilhem Janbon et al.   PLoS Genetics

Molecular Chaperone Functions in Protein Folding and Proteostasis

(2013) Yujin E. Kim et al.   Annual Review of Biochemistry

The fungal Achilles’ heel: targeting Hsp90 to cripple fungal pathogens

(2013) Leah E Cowen   CURRENT OPINION IN MICROBIOLOGY

The Cryptococcus neoformans Rim101 Transcription Factor Directly Regulates Genes Required for Adaptation to the Host

(2013) T. R. O'Meara et al.   MOLECULAR AND CELLULAR BIOLOGY

Mitochondrial Sorting and Assembly Machinery Subunit Sam37 in Candida albicans: Insight into the Roles of Mitochondria in Fitness, Cell Wall Integrity, and Virulence

(2012) Yue Qu et al.   EUKARYOTIC CELL

Cryptococcus neoformans Requires the ESCRT Protein Vps23 for Iron Acquisition from Heme, for Capsule Formation, and for Virulence

(2012) Guanggan Hu et al.   INFECTION AND IMMUNITY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Antifungal Spectrum, In Vivo Efficacy, and Structure–Activity Relationship of Ilicicolin H

(2012) Sheo B. Singh et al.   ACS Medicinal Chemistry Letters

FastCloning: a highly simplified, purification-free, sequence- and ligation-independent PCR cloning method

(2011) Chaokun Li et al.   BMC BIOTECHNOLOGY

Mitochondria and Fungal Pathogenesis: Drug Tolerance, Virulence, and Potential for Antifungal Therapy

(2011) Miguel Shingu-Vazquez et al.   EUKARYOTIC CELL

Proteomic Profiling of the Influence of Iron Availability on Cryptococcus gattii

(2011) Juliana Crestani et al.   JOURNAL OF PROTEOME RESEARCH

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

FungiDB: an integrated functional genomics database for fungi

(2011) J. E. Stajich et al.   NUCLEIC ACIDS RESEARCH

Identification of Genes Encoding Heat Shock Protein 40 Family and the Functional Characterization of Two Hsp40s, MHF16 and MHF21, in Magnaporthe oryzae

(2011) Mi-Hwa Yi et al.   Plant Pathology Journal

Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2

(2010) Michael J. Dagley et al.   MOLECULAR MICROBIOLOGY

Interaction of Cryptococcus neoformans Rim101 and Protein Kinase A Regulates Capsule

(2010) Teresa R. O'Meara et al.   PLoS Pathogens

Jid1 is a J-protein functioning in the mitochondrial matrix, unable to directly participate in endoplasmic reticulum associated protein degradation

(2009) Dejan Bursać et al.   FEBS LETTERS

The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulation

(2009) H. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease

(2009) Leah E. Cowen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Purification of Mitochondria from Yeast Cells

(2009) Christopher Gregg et al.   Jove-Journal of Visualized Experiments

Systematic Genetic Analysis of Virulence in the Human Fungal Pathogen Cryptococcus neoformans

(2008) Oliver W. Liu et al.   CELL