Inhibition of Classical and Alternative Modes of Respiration in Candida albicans Leads to Cell Wall Remodeling and Increased Macrophage Recognition

A mitochondrial proteomics view of complex I deficiency in Candida albicans

(2018) Xiaodong She et al.   MITOCHONDRION

Hypoxia Promotes Immune Evasion by Triggering β-Glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling

(2018) Arnab Pradhan et al.   mBio

Evasion of Immune Surveillance in Low Oxygen Environments Enhances Candida albicans Virulence

(2018) José Pedro Lopes et al.   mBio

Microbe Profile: Candida albicans: a shape-changing, opportunistic pathogenic fungus of humans

(2017) Neil A. R. Gow et al.   MICROBIOLOGY-SGM

Adaptation of Candida albicans to environmental pH induces cell wall remodelling and enhances innate immune recognition

(2017) Sarah L. Sherrington et al.   PLoS Pathogens

The Mitochondrial GTPase Gem1 Contributes to the Cell Wall Stress Response and Invasive Growth of Candida albicans

(2017) Barbara Koch et al.   Frontiers in Microbiology

Nitric oxide charged catheters as a potential strategy for prevention of hospital acquired infections

(2017) David Margel et al.   PLoS One

Candida albicans orf19.3727 encodes phytase activity and is essential for human tissue damage

(2017) Paul Wai-Kei Tsang et al.   PLoS One

Chromosome 5 of human pathogenCandida albicanscarries multiple genes for negative control of caspofungin and anidulafungin susceptibility

(2016) Sumanun Suwunnakorn et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Sustained Nitric Oxide-Releasing Nanoparticles Induce Cell Death in Candida albicans Yeast and Hyphal Cells, Preventing Biofilm FormationIn Vitroand in a Rodent Central Venous Catheter Model

(2016) Mohammed S. Ahmadi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cell wall integrity signalling in human pathogenic fungi

(2016) Karl Dichtl et al.   CELLULAR MICROBIOLOGY

Gaseous nitric oxide to treat antibiotic resistant bacterial and fungal lung infections in patients with cystic fibrosis: a phase I clinical study

(2016) Caroline Deppisch et al.   INFECTION

β-(1,3)-Glucan Unmasking in Some Candida albicans Mutants Correlates with Increases in Cell Wall Surface Roughness and Decreases in Cell Wall Elasticity

(2016) Sahar Hasim et al.   INFECTION AND IMMUNITY

The PathoYeastract database: an information system for the analysis of gene and genomic transcription regulation in pathogenic yeasts

(2016) Pedro Tiago Monteiro et al.   NUCLEIC ACIDS RESEARCH

Lactate signalling regulates fungal β-glucan masking and immune evasion

(2016) Elizabeth R. Ballou et al.   Nature Microbiology

Cell Wall N-Linked Mannoprotein Biosynthesis Requires Goa1p, a Putative Regulator of Mitochondrial Complex I in Candida albicans

(2016) Xiaodong She et al.   PLoS One

Fungal-specific subunits of theCandida albicansmitochondrial complex I drive diverse cell functions including cell wall synthesis

(2015) Xiaodong She et al.   CELLULAR MICROBIOLOGY

System-level impact of mitochondria on fungal virulence: to metabolism and beyond

(2015) Richard Calderone et al.   FEMS YEAST RESEARCH

Mitochondrial Activity and Cyr1 Are Key Regulators of Ras1 Activation of C. albicans Virulence Pathways

(2015) Nora Grahl et al.   PLoS Pathogens

Changes in glutathione-dependent redox status and mitochondrial energetic strategies are part of the adaptive response during the filamentation process in Candida albicans

(2014) H. Guedouari et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Rbf1, Hfl1 and Dbp4 of Candida albicans regulate common as well as transcription factor-specific mitochondrial and other cell activities

(2014) Kasra Khamooshi et al.   BMC GENOMICS

Are mitochondria the Achilles’ heel of the Kingdom Fungi?

(2014) Laurent Chatre et al.   CURRENT OPINION IN MICROBIOLOGY

Modeling the Transcriptional Regulatory Network That Controls the Early Hypoxic Response in Candida albicans

(2014) Adnane Sellam et al.   EUKARYOTIC CELL

Mitochondria InfluenceCDR1Efflux Pump Activity, Hog1-Mediated Oxidative Stress Pathway, Iron Homeostasis, and Ergosterol Levels in Candida albicans

(2013) Edwina Thomas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cell surface changes in theCandida albicansmitochondrial mutantgoa1Δ are associated with reduced recognition by innate immune cells

(2013) Xiaodong She et al.   CELLULAR MICROBIOLOGY

Genome-wide transcriptional profiling and enrichment mapping reveal divergent and conserved roles of Sko1 in the Candida albicans osmotic stress response

(2013) Dawn H. Marotta et al.   GENOMICS

The Mnn2 Mannosyltransferase Family Modulates Mannoprotein Fibril Length, Immune Recognition and Virulence of Candida albicans

(2013) Rebecca A. Hall et al.   PLoS Pathogens

Nitric oxide release: Part II. Therapeutic applications

(2012) Alexis W. Carpenter et al.   CHEMICAL SOCIETY REVIEWS

Mitochondrial Sorting and Assembly Machinery Subunit Sam37 in Candida albicans: Insight into the Roles of Mitochondria in Fitness, Cell Wall Integrity, and Virulence

(2012) Yue Qu et al.   EUKARYOTIC CELL

Stage Specific Assessment of Candida albicans Phagocytosis by Macrophages Identifies Cell Wall Composition and Morphogenesis as Key Determinants

(2012) Leanne E. Lewis et al.   PLoS Pathogens

Nitric Oxide Releasing Nanoparticles for Treatment of Candida Albicans Burn Infections

(2012) Chitralekha Macherla et al.   Frontiers in Microbiology

Mitochondria and Fungal Pathogenesis: Drug Tolerance, Virulence, and Potential for Antifungal Therapy

(2011) Miguel Shingu-Vazquez et al.   EUKARYOTIC CELL

Conserved and Divergent Roles of Bcr1 and CFEM Proteins in Candida parapsilosis and Candida albicans

(2011) Chen Ding et al.   PLoS One

Synthetic arylquinuclidine derivatives exhibit antifungal activity against Candida albicans, Candida tropicalis and Candida parapsilopsis

(2011) Kelly Ishida et al.   Annals of Clinical Microbiology and Antimicrobials

Efficacy of surface-generated nitric oxide against Candida albicans adhesion and biofilm formation

(2010) Benjamin J. Privett et al.   BIOFOULING

Regulation of the Hypoxic Response in Candida albicans

(2010) John M. Synnott et al.   EUKARYOTIC CELL

Contribution of Candida albicans Cell Wall Components to Recognition by and Escape from Murine Macrophages

(2010) C. G. J. McKenzie et al.   INFECTION AND IMMUNITY

Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2

(2010) Michael J. Dagley et al.   MOLECULAR MICROBIOLOGY

Phosphatidylserine synthase and phosphatidylserine decarboxylase are essential for cell wall integrity and virulence inCandida albicans

(2010) Ying-Lien Chen et al.   MOLECULAR MICROBIOLOGY

Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity

(2010) Suzanne M Noble et al.   NATURE GENETICS

A Phenotypic Profile of the Candida albicans Regulatory Network

(2009) Oliver R. Homann et al.   PLoS Genetics

A Gain-of-Function Mutation in the Transcription Factor Upc2p Causes Upregulation of Ergosterol Biosynthesis Genes and Increased Fluconazole Resistance in a ClinicalCandida albicansIsolate

(2008) Nico Dunkel et al.   EUKARYOTIC CELL

An integrated model of the recognition of Candida albicans by the innate immune system

(2007) Mihai G. Netea et al.   NATURE REVIEWS MICROBIOLOGY