System-level impact of mitochondria on fungal virulence: to metabolism and beyond

Hybrid histidine kinases in pathogenic fungi

(2015) Tatiana A. Defosse et al.   MOLECULAR MICROBIOLOGY

Determinants and Functions of Mitochondrial Behavior

(2014) Katherine Labbé et al.   Annual Review of Cell and Developmental Biology

Changes in glutathione-dependent redox status and mitochondrial energetic strategies are part of the adaptive response during the filamentation process in Candida albicans

(2014) H. Guedouari et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Rbf1, Hfl1 and Dbp4 of Candida albicans regulate common as well as transcription factor-specific mitochondrial and other cell activities

(2014) Kasra Khamooshi et al.   BMC GENOMICS

Anaerobic Bacteria Grow within Candida albicans Biofilms and Induce Biofilm Formation in Suspension Cultures

(2014) Emily P. Fox et al.   CURRENT BIOLOGY

A Dynamic Interface between Vacuoles and Mitochondria in Yeast

(2014) Yael Elbaz-Alon et al.   DEVELOPMENTAL CELL

Cellular Metabolism Regulates Contact Sites between Vacuoles and Mitochondria

(2014) Carina Hönscher et al.   DEVELOPMENTAL CELL

Mitochondrial ER Contacts Are Crucial for Mitophagy in Yeast

(2014) Stefan Böckler et al.   DEVELOPMENTAL CELL

Antifungal drug discovery: the process and outcomes

(2014) Richard Calderone et al.   Future Microbiology

Proteasomes Associated with the Blm10 Activator Protein Antagonize Mitochondrial Fission through Degradation of the Fission Protein Dnm1

(2014) Krisztina Tar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic control of cell death

(2014) D. R. Green et al.   SCIENCE

‘Division of labour’ in response to host oxidative burst drives a fatal Cryptococcus gattii outbreak

(2014) Kerstin Voelz et al.   Nature Communications

Antifungal Drug Development: Challenges, Unmet Clinical Needs, and New Approaches

(2014) T. Roemer et al.   Cold Spring Harbor Perspectives in Medicine

Analysis of Candida albicans Mutants Defective in the Cdk8 Module of Mediator Reveal Links between Metabolism and Biofilm Formation

(2014) Allia K. Lindsay et al.   PLoS Genetics

Microbial Egress: A Hitchhiker's Guide to Freedom

(2014) Ana Traven et al.   PLoS Pathogens

Comparative Phenotypic Analysis of the Major Fungal Pathogens Candida parapsilosis and Candida albicans

(2014) Linda M. Holland et al.   PLoS Pathogens

Mitochondria InfluenceCDR1Efflux Pump Activity, Hog1-Mediated Oxidative Stress Pathway, Iron Homeostasis, and Ergosterol Levels in Candida albicans

(2013) Edwina Thomas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The ins and outs of the intermembrane space: Diverse mechanisms and evolutionary rewiring of mitochondrial protein import routes

(2013) Victoria L. Hewitt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond

(2013) Jean E. Vance   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Epigenetic Silencing Mediates Mitochondria Stress-Induced Longevity

(2013) Elizabeth A. Schroeder et al.   Cell Metabolism

Cell surface changes in theCandida albicansmitochondrial mutantgoa1Δ are associated with reduced recognition by innate immune cells

(2013) Xiaodong She et al.   CELLULAR MICROBIOLOGY

Novel Insights into the Role of Neurospora crassa NDUFAF2, an Evolutionarily Conserved Mitochondrial Complex I Assembly Factor

(2013) B. Pereira et al.   MOLECULAR AND CELLULAR BIOLOGY

The Ancient and Widespread Nature of the ER–Mitochondria Encounter Structure

(2013) Jeremy G. Wideman et al.   MOLECULAR BIOLOGY AND EVOLUTION

Deficient Beta-Mannosylation of Candida albicans Phospholipomannan Affects the Proinflammatory Response in Macrophages

(2013) Audrey Devillers et al.   PLoS One

Azole Susceptibility and Transcriptome Profiling in Candida albicans Mitochondrial Electron Transport Chain Complex I Mutants

(2012) Nuo Sun et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The retrograde response: When mitochondrial quality control is not enough

(2012) S. Michal Jazwinski   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Recently Evolved Transcriptional Network Controls Biofilm Development in Candida albicans

(2012) Clarissa J. Nobile et al.   CELL

Mitochondrial Sorting and Assembly Machinery Subunit Sam37 in Candida albicans: Insight into the Roles of Mitochondria in Fitness, Cell Wall Integrity, and Virulence

(2012) Yue Qu et al.   EUKARYOTIC CELL

Caloric restriction restores the chronological life span of the goa1 null mutant of Candida albicans in spite of high cell levels of ROS

(2012) Hui Chen et al.   FUNGAL GENETICS AND BIOLOGY

Dysfunctional Mitochondria Modulate cAMP-PKA Signaling and Filamentous and Invasive Growth of Saccharomyces cerevisiae

(2012) A. Aun et al.   GENETICS

Members 5 and 6 of the Candida albicans BMT family encode enzymes acting specifically on  -mannosylation of the phospholipomannan cell-wall glycosphingolipid

(2012) C. Mille et al.   GLYCOBIOLOGY

Time Course Analysis of Candida albicans Metabolites during Biofilm Development

(2012) ZhenYu Zhu et al.   JOURNAL OF PROTEOME RESEARCH

The mannan ofCandida albicanslacking β-1,2-linked oligomannosides increases the production of inflammatory cytokines by dendritic cells

(2012) Keigo Ueno et al.   MEDICAL MYCOLOGY

Cell Differentiation within a Yeast Colony: Metabolic and Regulatory Parallels with a Tumor-Affected Organism

(2012) Michal Čáp et al.   MOLECULAR CELL

Transcriptional Profiling of a Yeast Colony Provides New Insight into the Heterogeneity of Multicellular Fungal Communities

(2012) Ana Traven et al.   PLoS One

A model system for mitochondrial biogenesis reveals evolutionary rewiring of protein import and membrane assembly pathways

(2012) V. L. Hewitt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding mitochondrial complex I assembly in health and disease

(2011) Masakazu Mimaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondria regulate autophagy by conserved signalling pathways

(2011) Martin Graef et al.   EMBO JOURNAL

Mitochondria and Fungal Pathogenesis: Drug Tolerance, Virulence, and Potential for Antifungal Therapy

(2011) Miguel Shingu-Vazquez et al.   EUKARYOTIC CELL

Enzymatic Dysfunction of Mitochondrial Complex I of the Candida albicansgoa1Mutant Is Associated with Increased Reactive Oxidants and Cell Death

(2011) Dongmei Li et al.   EUKARYOTIC CELL

Contribution of the glycolytic flux and hypoxia adaptation to efficient biofilm formation by Candida albicans

(2011) Julie Bonhomme et al.   MOLECULAR MICROBIOLOGY

Growth of Candida albicans hyphae

(2011) Peter E. Sudbery   NATURE REVIEWS MICROBIOLOGY

Intestinal Resident Yeast Candida glabrata Requires Cyb2p-Mediated Lactate Assimilation to Adapt in Mouse Intestine

(2011) Keigo Ueno et al.   PLoS One

Mdm10 as a dynamic constituent of the TOB/SAM complex directs coordinated assembly of Tom40

(2010) Koji Yamano et al.   EMBO REPORTS

ERMES-mediated ER-mitochondria contacts: molecular hubs for the regulation of mitochondrial biology

(2010) B. Kornmann et al.   JOURNAL OF CELL SCIENCE

The Subunit Composition of Mitochondrial NADH:Ubiquinone Oxidoreductase (Complex I) FromPichia pastoris

(2010) Hannah R. Bridges et al.   MOLECULAR & CELLULAR PROTEOMICS

Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2

(2010) Michael J. Dagley et al.   MOLECULAR MICROBIOLOGY

The energetics of genome complexity

(2010) Nick Lane et al.   NATURE

Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity

(2010) Suzanne M Noble et al.   NATURE GENETICS

Genetic control of Candida albicans biofilm development

(2010) Jonathan S. Finkel et al.   NATURE REVIEWS MICROBIOLOGY

Pathway analysis of Candida albicans survival and virulence determinants in a murine infection model

(2010) J. M. Becker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Importing Mitochondrial Proteins: Machineries and Mechanisms

(2009) Agnieszka Chacinska et al.   CELL

Goa1p ofCandida albicansLocalizes to the Mitochondria during Stress and Is Required for Mitochondrial Function and Virulence

(2009) Adrienne Bambach et al.   EUKARYOTIC CELL

The Ras/cAMP/PKA signaling pathway and virulence inCandida albicans

(2009) Deborah A Hogan et al.   Future Microbiology

The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulation

(2009) H. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

A Phenotypic Profile of the Candida albicans Regulatory Network

(2009) Oliver R. Homann et al.   PLoS Genetics

Mitochondria—A Nexus for Aging, Calorie Restriction, and Sirtuins?

(2008) Leonard Guarente   CELL

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL

 -1,2 Oligomannose Adhesin Epitopes Are Widely Distributed over the Different Families of Candida albicans Cell Wall Mannoproteins and Are Associated through both N- and O-Glycosylation Processes

(2008) C. Fradin et al.   INFECTION AND IMMUNITY

Identification of a New Family of Genes Involved in β-1,2-Mannosylation of Glycans inPichia pastorisandCandida albicans

(2008) Céline Mille et al.   JOURNAL OF BIOLOGICAL CHEMISTRY