Small molecules block the interaction between porcine reproductive and respiratory syndrome virus and CD163 receptor and the infection of pig cells

Miro1 Marks Parkinson’s Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson’s Models

(2019) Chung-Han Hsieh et al.   Cell Metabolism

Highly Efficient Generation of Pigs Harboring a Partial Deletion of the CD163 SRCR5 Domain, Which Are Fully Resistant to Porcine Reproductive and Respiratory Syndrome Virus 2 Infection

(2019) Chunhe Guo et al.   Frontiers in Immunology

MYH9 Aggregation Induced by Direct Interaction With PRRSV GP5 Ectodomain Facilitates Viral Internalization by Permissive Cells

(2019) Biyun Xue et al.   Frontiers in Microbiology

Pigs lacking the scavenger receptor cysteine-rich domain 5 of CD163 are resistant to PRRSV-1 infection.

(2018) Christine Burkard et al.   JOURNAL OF VIROLOGY

Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide

(2018) Manabu Kaneko et al.   Scientific Reports

Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function

(2017) Christine Burkard et al.   PLoS Pathogens

Improved Vaccine against PRRSV: Current Progress and Future Perspective

(2017) Yuchen Nan et al.   Frontiers in Microbiology

The Crystal Structure of the Fifth Scavenger Receptor Cysteine-Rich Domain of Porcine CD163 Reveals an Important Residue Involved in Porcine Reproductive and Respiratory Syndrome Virus Infection

(2016) Hongfang Ma et al.   JOURNAL OF VIROLOGY

Replacement of Porcine CD163 Scavenger Receptor Cysteine-Rich Domain 5 with a CD163-Like Homolog Confers Resistance of Pigs to Genotype 1 but Not Genotype 2 Porcine Reproductive and Respiratory Syndrome Virus

(2016) Kevin D. Wells et al.   JOURNAL OF VIROLOGY

Irbesartan, an FDA approved drug for hypertension and diabetic nephropathy, is a potent inhibitor for hepatitis B virus entry by disturbing Na+-dependent taurocholate cotransporting polypeptide activity

(2015) Xue-jun Wang et al.   ANTIVIRAL RESEARCH

A Novel Tricyclic Polyketide, Vanitaracin A, Specifically Inhibits the Entry of Hepatitis B and D Viruses by Targeting Sodium Taurocholate Cotransporting Polypeptide

(2015) Manabu Kaneko et al.   JOURNAL OF VIROLOGY

Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus

(2015) Kristin M Whitworth et al.   NATURE BIOTECHNOLOGY

Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP)

(2013) Koichi Watashi et al.   HEPATOLOGY

Cyclosporin A inhibits hepatitis B and hepatitis D virus entry by cyclophilin-independent interference with the NTCP receptor

(2013) Shirin Nkongolo et al.   JOURNAL OF HEPATOLOGY

An Intact Sialoadhesin (Sn/SIGLEC1/CD169) Is Not Required for Attachment/Internalization of the Porcine Reproductive and Respiratory Syndrome Virus

(2013) R. S. Prather et al.   JOURNAL OF VIROLOGY

Influence of N-linked glycosylation of minor proteins of porcine reproductive and respiratory syndrome virus on infectious virus recovery and receptor interaction

(2012) Zuzhang Wei et al.   VIROLOGY

An improved bimolecular fluorescence complementation assay with a high signal-to-noise ratio

(2010) Yutaka Kodama* et al.   BIOTECHNIQUES

Susceptible cell lines for the production of porcine reproductive and respiratory syndrome virus by stable transfection of sialoadhesin and CD163

(2010) Iris Delrue et al.   BMC BIOTECHNOLOGY

Porcine reproductive and respiratory syndrome virus entry into the porcine macrophage

(2010) W. Van Breedam et al.   JOURNAL OF GENERAL VIROLOGY

The ever-expanding diversity of porcine reproductive and respiratory syndrome virus

(2010) Michael P. Murtaugh et al.   VIRUS RESEARCH

The role of porcine reproductive and respiratory syndrome (PRRS) virus structural and non-structural proteins in virus pathogenesis

(2010) Nedzad Music et al.   ANIMAL HEALTH RESEARCH REVIEWS

The porcine reproductive and respiratory syndrome virus requires trafficking through CD163-positive early endosomes, but not late endosomes, for productive infection

(2009) Hanne Van Gorp et al.   ARCHIVES OF VIROLOGY

Generation of a porcine alveolar macrophage cell line for the growth of porcine reproductive and respiratory syndrome virus

(2009) Yoo Jin Lee et al.   JOURNAL OF VIROLOGICAL METHODS

Identification of the CD163 Protein Domains Involved in Infection of the Porcine Reproductive and Respiratory Syndrome Virus

(2009) H. Van Gorp et al.   JOURNAL OF VIROLOGY

The Minor Envelope Glycoproteins GP2a and GP4 of Porcine Reproductive and Respiratory Syndrome Virus Interact with the Receptor CD163

(2009) P. B. Das et al.   JOURNAL OF VIROLOGY

HIV-1 entry inhibitors: an overview

(2009) Daniel R Kuritzkes   Current Opinion in HIV and AIDS

Sialoadhesin and CD163 join forces during entry of the porcine reproductive and respiratory syndrome virus

(2008) H. Van Gorp et al.   JOURNAL OF GENERAL VIROLOGY

HIV entry inhibitors and their potential in HIV therapy

(2008) Keduo Qian et al.   MEDICINAL RESEARCH REVIEWS