The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells
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Title
The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells
Authors
Keywords
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Journal
Science Signaling
Volume 13, Issue 642, Pages eaaz8240
Publisher
American Association for the Advancement of Science (AAAS)
Online
2020-07-29
DOI
10.1126/scisignal.aaz8240
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Note: Only part of the references are listed.- FUN14 domain-containing 1 promotes breast cancer proliferation and migration by activating calcium-NFATC1-BMI1 axis
- (2019) Lianpin Wu et al. EBioMedicine
- Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth
- (2019) Ekta Agarwal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cellular Plasticity in Cancer
- (2019) Salina Yuan et al. Cancer Discovery
- Autophagy and mitophagy in cancer metabolic remodelling
- (2019) Fabio Ferro et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Akt phosphorylation of mitochondrial Lonp1 protease enables oxidative metabolism and advanced tumor traits
- (2019) Jagadish C. Ghosh et al. ONCOGENE
- Mitochondrial plasticity in cell fate regulation
- (2019) Amir Bahat et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial dynamics in adaptive and maladaptive cellular stress responses
- (2018) Verónica Eisner et al. NATURE CELL BIOLOGY
- The Role of Mitochondrial H+-ATP Synthase in Cancer
- (2018) Pau B. Esparza-Moltó et al. Frontiers in Oncology
- Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance
- (2018) Kwon-Ho Song et al. JOURNAL OF CLINICAL INVESTIGATION
- FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models
- (2018) Jianwen Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer
- (2017) M. Cecilia Caino et al. JOURNAL OF CLINICAL INVESTIGATION
- Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration
- (2017) Max-Hinderk Schuler et al. MOLECULAR BIOLOGY OF THE CELL
- Expanding perspectives on the significance of mitophagy in cancer
- (2017) Lauren E. Drake et al. SEMINARS IN CANCER BIOLOGY
- Microenvironment-derived factors driving metastatic plasticity in melanoma
- (2017) Isabella S. Kim et al. Nature Communications
- ROS Control Mitochondrial Motility through p38 and the Motor Adaptor Miro/Trak
- (2017) Valentina Debattisti et al. Cell Reports
- Metabolic Plasticity as a Determinant of Tumor Growth and Metastasis
- (2016) Camille Lehuédé et al. CANCER RESEARCH
- Mitochondria and Cancer
- (2016) Sejal Vyas et al. CELL
- FUNDC1 regulates mitochondrial dynamics at the ER–mitochondrial contact site under hypoxic conditions
- (2016) Wenxian Wu et al. EMBO JOURNAL
- AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion
- (2016) Brian Cunniff et al. MOLECULAR BIOLOGY OF THE CELL
- Metabolism and the UPR mt
- (2016) Yi-Fan Lin et al. MOLECULAR CELL
- A neuronal network of mitochondrial dynamics regulates metastasis
- (2016) M. Cecilia Caino et al. Nature Communications
- A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria
- (2016) Kenneth Robert Pryde et al. Cell Reports
- The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis
- (2016) Jae Ho Seo et al. PLOS BIOLOGY
- Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia
- (2015) Alicia Cole et al. CANCER CELL
- Evolution of Mitochondria as Signaling Organelles
- (2015) Navdeep S. Chandel Cell Metabolism
- 2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling
- (2015) Xudong Fu et al. Cell Metabolism
- Molecular Pathways: Mitochondrial Reprogramming in Tumor Progression and Therapy
- (2015) M. C. Caino et al. CLINICAL CANCER RESEARCH
- Pyruvate carboxylase is critical for non–small-cell lung cancer proliferation
- (2015) Katherine Sellers et al. JOURNAL OF CLINICAL INVESTIGATION
- The Molecular Motor F-ATP Synthase Is Targeted by the Tumoricidal Protein HAMLET
- (2015) James Ho et al. JOURNAL OF MOLECULAR BIOLOGY
- Oxidative stress inhibits distant metastasis by human melanoma cells
- (2015) Elena Piskounova et al. NATURE
- MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins
- (2015) Sarah E. Calvo et al. NUCLEIC ACIDS RESEARCH
- PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
- (2015) M. Cecilia Caino et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial trafficking in neurons and the role of the Miro family of GTPase proteins
- (2015) Nicol Birsa et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins
- (2015) Ayenachew Bezawork-Geleta et al. Scientific Reports
- Directed migration of mesenchymal cells: where signaling and the cytoskeleton meet
- (2014) James E Bear et al. CURRENT OPINION IN CELL BIOLOGY
- ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy
- (2014) W. Wu et al. EMBO REPORTS
- Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
- (2014) Andrea Viale et al. NATURE
- PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
- (2014) Valerie S. LeBleu et al. NATURE CELL BIOLOGY
- ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity
- (2014) Pedro M. Quirós et al. Cell Reports
- A Mitochondrial Switch Promotes Tumor Metastasis
- (2014) Paolo E. Porporato et al. Cell Reports
- Mitochondrial Localization and the Persistent Migration of Epithelial Cancer cells
- (2013) Salil P. Desai et al. BIOPHYSICAL JOURNAL
- The Cancer Diaspora: Metastasis beyond the Seed and Soil Hypothesis
- (2013) K. J. Pienta et al. CLINICAL CANCER RESEARCH
- Landscape of the mitochondrial Hsp90 metabolome in tumours
- (2013) Young Chan Chae et al. Nature Communications
- Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
- (2012) Lei Liu et al. NATURE CELL BIOLOGY
- Mitochondrial dynamics regulates migration and invasion of breast cancer cells
- (2012) J Zhao et al. ONCOGENE
- Redox regulation of cell migration and adhesion
- (2012) Thomas Ryan Hurd et al. TRENDS IN CELL BIOLOGY
- Mitochondria and cell death: outer membrane permeabilization and beyond
- (2010) Stephen W. G. Tait et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
- (2010) F. Weinberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
- (2008) Ralph J. DeBerardinis et al. Cell Metabolism
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
- ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis
- (2008) K. Ishikawa et al. SCIENCE
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