Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance

NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis

(2016) Hui Wang et al.   Science Translational Medicine

Reactive oxygen species in redox cancer therapy

(2015) Lingying Tong et al.   CANCER LETTERS

NANOG signaling promotes metastatic capability of immunoedited tumor cells

(2015) Hyo-Jung Lee et al.   CLINICAL & EXPERIMENTAL METASTASIS

Gain of HIF-1  under Normoxia in Cancer Mediates Immune Adaptation through the AKT/ERK and VEGFA Axes

(2015) Y.-H. Lee et al.   CLINICAL CANCER RESEARCH

Oxidative stress inhibits distant metastasis by human melanoma cells

(2015) Elena Piskounova et al.   NATURE

Mitochondrial ROS and cancer drug resistance: Implications for therapy

(2015) Imoh S. Okon et al.   PHARMACOLOGICAL RESEARCH

Immune-mediated tumor evolution: Nanog links the emergence of a stem like cancer cell state and immune evasion

(2014) Chih-Ping Mao et al.   OncoImmunology

Nanog signaling in cancer promotes stem-like phenotype and immune evasion

(2012) Kyung Hee Noh et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression of tumour-specific antigens underlies cancer immunoediting

(2012) Michel DuPage et al.   NATURE

Natural Innate and Adaptive Immunity to Cancer

(2011) Matthew D. Vesely et al.   Annual Review of Immunology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

(2011) Gina M. DeNicola et al.   NATURE

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acquired Resistance to BRAF Inhibitors Mediated by a RAF Kinase Switch in Melanoma Can Be Overcome by Cotargeting MEK and IGF-1R/PI3K

(2010) Jessie Villanueva et al.   CANCER CELL

Cancer metabolism: The Warburg effect today

(2010) Leonardo M.R. Ferreira   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

Clues from cell metabolism

(2010) William G. Kaelin et al.   NATURE

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

(2010) Cory M. Johannessen et al.   NATURE

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

(2010) Ramin Nazarian et al.   NATURE

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Activation of Akt as a Mechanism for Tumor Immune Evasion

(2008) Kyung Hee Noh et al.   MOLECULAR THERAPY