Kinetically distinct processing pathways diversify the CD8+T cell response to a single viral epitope

Recognition and Degradation of Mislocalized Proteins in Health and Disease

(2019) Ramanujan S. Hegde et al.   Cold Spring Harbor Perspectives in Biology

Engineering an Artificial T‐Cell Stimulating Matrix for Immunotherapy

(2019) John W. Hickey et al.   ADVANCED MATERIALS

Peptide Channeling: The Key to MHC Class I Immunosurveillance?

(2019) Jonathan W. Yewdell et al.   TRENDS IN CELL BIOLOGY

Kinetic Modeling of Virus Growth in Cells

(2018) John Yin et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

TCR Signaling: Mechanisms of Initiation and Propagation

(2018) Adam H. Courtney et al.   TRENDS IN BIOCHEMICAL SCIENCES

Quality Control of Orphaned Proteins

(2018) Szymon Juszkiewicz et al.   MOLECULAR CELL

The Guanylate Cyclase C—cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia

(2018) Jeffrey A. Rappaport et al.   Frontiers in Oncology

The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma

(2017) Ronan Le Moigne et al.   MOLECULAR CANCER THERAPEUTICS

New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation

(2017) Ling Qi et al.   TRENDS IN CELL BIOLOGY

Role of Different Subpopulations of CD8+ T Cells during HIV Exposure and Infection

(2017) Sandra Milena Gonzalez et al.   Frontiers in Immunology

Defining Viral Defective Ribosomal Products: Standard and Alternative Translation Initiation Events Generate a Common Peptide from Influenza A Virus M2 and M1 mRNAs

(2016) Ning Yang et al.   JOURNAL OF IMMUNOLOGY

Balancing Immune Protection and Immune Pathology by CD8+ T-Cell Responses to Influenza Infection

(2016) Susu Duan et al.   Frontiers in Immunology

Discovery of a First-in-Class, Potent, Selective, and Orally Bioavailable Inhibitor of the p97 AAA ATPase (CB-5083)

(2015) Han-Jie Zhou et al.   JOURNAL OF MEDICINAL CHEMISTRY

ER Stress-Induced Clearance of Misfolded GPI-Anchored Proteins via the Secretory Pathway

(2014) Prasanna Satpute-Krishnan et al.   CELL

Re-examining class-I presentation and the DRiP hypothesis

(2014) Kenneth L. Rock et al.   TRENDS IN IMMUNOLOGY

Substrate-Induced Protein Stabilization Reveals a Predominant Contribution from Mature Proteins to Peptides Presented on MHC Class I

(2013) J. D. Colbert et al.   JOURNAL OF IMMUNOLOGY

A Cotranslational Ubiquitination Pathway for Quality Control of Misfolded Proteins

(2013) Feng Wang et al.   MOLECULAR CELL

Principles of Cotranslational Ubiquitination and Quality Control at the Ribosome

(2013) Stefanie Duttler et al.   MOLECULAR CELL

Proteome Dynamics: Revisiting Turnover with a Global Perspective

(2012) Amy J. Claydon et al.   MOLECULAR & CELLULAR PROTEOMICS

Hydrophobicity as a driver of MHC class I antigen processing

(2011) Lan Huang et al.   EMBO JOURNAL

A Quantitative Spatial Proteomics Analysis of Proteome Turnover in Human Cells

(2011) François-Michel Boisvert et al.   MOLECULAR & CELLULAR PROTEOMICS

Major source of antigenic peptides for the MHC class I pathway is produced during the pioneer round of mRNA translation

(2011) S. Apcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The dynamic state of protein turnover: It's about time

(2011) Izumi V. Hinkson et al.   TRENDS IN CELL BIOLOGY

Expression Regulation of Major Histocompatibility Complex Class I and Class II Encoding Genes

(2011) Peter J. van den Elsen   Frontiers in Immunology

BAG-6 is essential for selective elimination of defective proteasomal substrates

(2010) Ryosuke Minami et al.   JOURNAL OF CELL BIOLOGY

Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein

(2010) Neena S. Rane et al.   JOURNAL OF CELL BIOLOGY

The ERAD Inhibitor Eeyarestatin I Is a Bifunctional Compound with a Membrane-Binding Domain and a p97/VCP Inhibitory Group

(2010) Qiuyan Wang et al.   PLoS One

Direct Presentation Is Sufficient for an Efficient Anti-Viral CD8+ T Cell Response

(2010) Ren-Huan Xu et al.   PLoS Pathogens

T cell sensitivity and the outcome of viral infection

(2009) L. J. Walker et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum

(2009) B. C. S. Cross et al.   JOURNAL OF CELL SCIENCE

The Exception that Reinforces the Rule: Crosspriming by Cytosolic Peptides that Escape Degradation

(2008) Avital Lev et al.   IMMUNITY

Guanylyl Cyclase C–Induced Immunotherapeutic Responses Opposing Tumor Metastases Without Autoimmunity

(2008) Adam E. Snook et al.   JNCI-Journal of the National Cancer Institute