Engineering an Artificial T‐Cell Stimulating Matrix for Immunotherapy

Separating T Cell Targeting Components onto Magnetically Clustered Nanoparticles Boosts Activation

(2018) Alyssa K. Kosmides et al.   NANO LETTERS

Scaffolds that mimic antigen-presenting cells enable ex vivo expansion of primary T cells

(2018) Alexander S Cheung et al.   NATURE BIOTECHNOLOGY

Efficient magnetic enrichment of antigen-specific T cells by engineering particle properties

(2018) John W. Hickey et al.   BIOMATERIALS

Biologically Inspired Design of Nanoparticle Artificial Antigen-Presenting Cells for Immunomodulation

(2017) John W. Hickey et al.   NANO LETTERS

Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy

(2015) Karlo Perica et al.   ACS Nano

mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation

(2015) Kristen N. Pollizzi et al.   JOURNAL OF CLINICAL INVESTIGATION

Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime

(2015) Dibyendu Kumar Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Substrate stress relaxation regulates cell spreading

(2015) Ovijit Chaudhuri et al.   Nature Communications

Accumulation of Dynamic Catch Bonds between TCR and Agonist Peptide-MHC Triggers T Cell Signaling

(2014) Baoyu Liu et al.   CELL

Biopolymer implants enhance the efficacy of adoptive T-cell therapy

(2014) Sirkka B Stephan et al.   NATURE BIOTECHNOLOGY

A carbon nanotube–polymer composite for T-cell therapy

(2014) Tarek R. Fadel et al.   Nature Nanotechnology

Mechanotransduction and extracellular matrix homeostasis

(2014) Jay D. Humphrey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Short Laminin Peptide for Improved Neural Stem Cell Growth

(2014) Xiaowei Li et al.   Stem Cells Translational Medicine

Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8+ T cells

(2014) Seth M Pollack et al.   Journal for ImmunoTherapy of Cancer

Sprouty-2 regulates HIV-specific T cell polyfunctionality

(2013) Yen-Ling Chiu et al.   JOURNAL OF CLINICAL INVESTIGATION

MR Elastography of the Liver and the Spleen Using a Piezoelectric Driver, Single-Shot Wave-Field Acquisition, and Multifrequency Dual Parameter Reconstruction

(2013) Sebastian Hirsch et al.   MAGNETIC RESONANCE IN MEDICINE

Fine Tuning and Efficient T Cell Activation with Stimulatory aCD3 Nanoarrays

(2013) Jovana Matic et al.   NANO LETTERS

T Cell Activation is Determined by the Number of Presented Antigens

(2013) Janosch Deeg et al.   NANO LETTERS

Mechanosensing in T Lymphocyte Activation

(2012) Edward Judokusumo et al.   BIOPHYSICAL JOURNAL

Engineering an in situ crosslinkable hydrogel for enhanced remyelination

(2012) Xiaowei Li et al.   FASEB JOURNAL

Substrate Rigidity Regulates Human T Cell Activation and Proliferation

(2012) R. S. O'Connor et al.   JOURNAL OF IMMUNOLOGY

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

How does the kinase Lck phosphorylate the T cell receptor? Spatial organization as a regulatory mechanism

(2012) Jérémie Rossy et al.   Frontiers in Immunology

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

(2011) Michelle C. Mendoza et al.   TRENDS IN BIOCHEMICAL SCIENCES

The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels

(2010) Yuguo Lei et al.   BIOMATERIALS

Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy

(2010) C. S. Hinrichs et al.   BLOOD

How chronic viral infections impact on antigen-specific T-cell responses

(2010) Helge Frebel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Alterations of dendritic cell subsets in the peripheral circulation of patients with cervical carcinoma

(2010) Feng Ye et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cutting Edge: Mechanical Forces Acting on T Cells Immobilized via the TCR Complex Can Trigger TCR Signaling

(2010) Y. C. Li et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cell Inhibition Is Connected to Exhaustion of CD8+ T Cell Polyfunctionality during Chronic Hepatitis C Virus Infection

(2010) I. G. Rodrigue-Gervais et al.   JOURNAL OF IMMUNOLOGY

CD44 interacts directly with Lck in a zinc-dependent manner

(2010) Dennis C. Lefebvre et al.   MOLECULAR IMMUNOLOGY

Mechanical regulation of cell function with geometrically modulated elastomeric substrates

(2010) Jianping Fu et al.   NATURE METHODS

Thermosensitive injectable hyaluronic acid hydrogel for adipose tissue engineering

(2009) Huaping Tan et al.   BIOMATERIALS

Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

(2009) M. Ahmadzadeh et al.   BLOOD

Immunological functions of hyaluronan and its receptors in the lymphatics

(2009) David G. Jackson   IMMUNOLOGICAL REVIEWS

The αβ T Cell Receptor Is an Anisotropic Mechanosensor

(2009) Sun Taek Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Intensity Lymphodepletion Enhances Tumor Treatment Efficacy of Adoptively Transferred Tumor-specific T Cells

(2009) Claudia Wrzesinski et al.   JOURNAL OF IMMUNOTHERAPY

T cell antigen receptor signaling and immunological synapse stability require myosin IIA

(2009) Tal Ilani et al.   NATURE IMMUNOLOGY

Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties

(2009) April M. Kloxin et al.   SCIENCE

Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration

(2008) Soo-Hong Lee et al.   BIOMATERIALS

Polyfunctional HCV-specific T-cell responses are associated with effective control of HCV replication

(2008) Donatella Ciuffreda et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates

(2008) Carolina Berger et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanotransduction gone awry

(2008) Diana E. Jaalouk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY