Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume -, Issue -, Pages 202008671
Publisher
Proceedings of the National Academy of Sciences
Online
2020-08-13
DOI
10.1073/pnas.2008671117
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome.
- (2020) Evgeny B Pichkur et al. RNA
- Sarecycline: First Global Approval
- (2019) Emma D. Deeks DRUGS
- High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition.
- (2019) Maxim S. Svetlov et al. RNA
- Retapamulin-Assisted Ribosome Profiling Reveals the Alternative Bacterial Proteome
- (2019) Sezen Meydan et al. MOLECULAR CELL
- Structure of Dirithromycin Bound to the Bacterial Ribosome Suggests New Ways for Rational Improvement of Macrolides
- (2019) Nelli F. Khabibullina et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design
- (2018) Jinzhong Lin et al. Annual Review of Biochemistry
- Context-Specific Action of Ribosomal Antibiotics
- (2018) Nora Vázquez-Laslop et al. Annual Review of Microbiology
- Odilorhabdins, Antibacterial Agents that Cause Miscoding by Binding at a New Ribosomal Site
- (2018) Lucile Pantel et al. MOLECULAR CELL
- Microbiological Profile of Sarecycline, a Novel Targeted Spectrum Tetracycline for the Treatment of Acne Vulgaris
- (2018) George Zhanel et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Comprehensive identification of translation start sites by tetracycline-inhibited ribosome profiling
- (2016) Kenji Nakahigashi et al. DNA RESEARCH
- Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center
- (2016) James Marks et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly
- (2015) Yury S Polikanov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9-Å resolution
- (2015) Stefan Arenz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly
- (2015) Yury S Polikanov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Tetracycline antibiotics and resistance mechanisms
- (2014) Fabian Nguyen et al. BIOLOGICAL CHEMISTRY
- Negamycin Interferes with Decoding and Translocation by Simultaneous Interaction with rRNA and tRNA
- (2014) Yury S. Polikanov et al. MOLECULAR CELL
- Tools for Characterizing Bacterial Protein Synthesis Inhibitors
- (2013) Cédric Orelle et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Ribosome-targeting antibiotics and mechanisms of bacterial resistance
- (2013) Daniel N. Wilson NATURE REVIEWS MICROBIOLOGY
- Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis
- (2013) L. Jenner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanism of tetracycline resistance by ribosomal protection protein Tet(O)
- (2013) Wen Li et al. Nature Communications
- Structural basis for TetM-mediated tetracycline resistance
- (2012) A. Donhofer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature
- (2010) Michael O. Griffin et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Probing Translation with Small-Molecule Inhibitors
- (2010) Scott C. Blanchard et al. CHEMISTRY & BIOLOGY
- Molecular Mechanism of Drug-Dependent Ribosome Stalling
- (2008) Nora Vazquez-Laslop et al. MOLECULAR CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More