NHD2-15, a novel antagonist of Growth Factor Receptor-Bound Protein-2 (GRB2), inhibits leukemic proliferation

Using zebrafish models of leukemia to streamline drug screening and discovery

(2017) Adam P. Deveau et al.   EXPERIMENTAL HEMATOLOGY

Tyrosine kinase inhibitors in chronic myeloid leukaemia: which, when, for whom?

(2016) Gianantonio Rosti et al.   Nature Reviews Clinical Oncology

Hematopoietic stem cells: concepts, definitions, and the new reality

(2015) C. J. Eaves   BLOOD

The Capable ABL: What Is Its Biological Function?

(2014) J. Y. J. Wang   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms of Activation of Receptor Tyrosine Kinases: Monomers or Dimers

(2014) Ichiro Maruyama   Cells

The Multifaceted Functions of Neutrophils

(2013) Tanya N. Mayadas et al.   Annual Review of Pathology-Mechanisms of Disease

Transition metal free hydrolysis/cyclization strategy in a single pot: synthesis of fused furo N-heterocycles of pharmacological interest

(2013) Ali Nakhi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

AlCl3 induced (hetero)arylation of 2,3-dichloroquinoxaline: A one-pot synthesis of mono/disubstituted quinoxalines as potential antitubercular agents

(2012) K. Shiva Kumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Zebrafish screen identifies novel compound with selective toxicity against leukemia

(2012) S. Ridges et al.   BLOOD

Cu-Catalyzed Reaction of 1,2-Dihalobenzenes with 1,3-Cyclohexanediones for the Synthesis of 3,4-Dihydrodibenzo[b,d]furan-1(2H)-ones

(2012) Nayyef Aljaar et al.   JOURNAL OF ORGANIC CHEMISTRY

Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036

(2011) Wayne W. Chan et al.   CANCER CELL

Benzopyrazine derivatives: A novel class of growth factor receptor bound protein 7 antagonists

(2010) Nigus D. Ambaye et al.   BIOORGANIC & MEDICINAL CHEMISTRY

In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days

(2010) J. Pillay et al.   BLOOD

Targeting the BCR-ABL Signaling Pathway in Therapy-Resistant Philadelphia Chromosome-Positive Leukemia

(2010) T. O'Hare et al.   CLINICAL CANCER RESEARCH

Docking proteins

(2010) Tilman Brummer et al.   FEBS Journal

A Chemical Genetic Screen in Zebrafish for Pathways Interacting with cdx4 in Primitive Hematopoiesis

(2010) Elizabeth J. Paik et al.   Zebrafish

Zebrafish kidney stromal cell lines support multilineage hematopoiesis

(2009) D. L. Stachura et al.   BLOOD

Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation

(2009) Jing-Ruey J Yeh et al.   Nature Chemical Biology

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL

Phospho-CRKL monitoring for the assessment of BCR-ABL activity in imatinib-resistant chronic myeloid leukemia or Ph+ acute lymphoblastic leukemia patients treated with nilotinib

(2008) P. La Rosee et al.   HAEMATOLOGICA