Facial shape and allometry quantitative trait locus intervals in the Diversity Outbred mouse are enriched for known skeletal and facial development genes

Mouse Skull Mean Shape and Shape Robustness Rely on Different Genetic Architectures and Different Loci

(2019) Ceferino Varón-González et al.   Frontiers in Genetics

Cleaning Genotype Data from Diversity Outbred Mice

(2019) Karl W. Broman et al.   G3-Genes Genomes Genetics

Hunting for genes that shape human faces: Initial successes and challenges for the future

(2019) Seth M. Weinberg et al.   Orthodontics & Craniofacial Research

Identification of five novel genetic loci related to facial morphology by genome-wide association studies

(2018) Seongwon Cha et al.   BMC GENOMICS

Genome-wide mapping of global-to-local genetic effects on human facial shape

(2018) Peter Claes et al.   NATURE GENETICS

Genetics of the human face: Identification of large-effect single gene variants

(2018) Daniel J. M. Crouch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Resolution Epigenomic Atlas of Human Embryonic Craniofacial Development

(2018) Andrea Wilderman et al.   Cell Reports

Developmental constraint through negative pleiotropy in the zygomatic arch

(2018) Christopher J. Percival et al.   EvoDevo

Epistasis regulates the developmental stability of the mouse craniofacial shape

(2018) Ceferino Varón-González et al.   HEREDITY

Complex-Trait Prediction in the Era of Big Data

(2018) Gustavo de los Campos et al.   TRENDS IN GENETICS

R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multi-parent Populations

(2018) Karl W. Broman et al.   GENETICS

Facial Genetics: A Brief Overview

(2018) Stephen Richmond et al.   Frontiers in Genetics

Zinc-finger transcription factor Odd-skipped related 1 regulates cranial bone formation

(2017) Shinji Kawai et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Quantitative trait mapping in Diversity Outbred mice identifies two genomic regions associated with heart size

(2017) John R. Shorter et al.   MAMMALIAN GENOME

Changes in human skull morphology across the agricultural transition are consistent with softer diets in preindustrial farming groups

(2017) David C. Katz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental nonlinearity drives phenotypic robustness

(2017) Rebecca M. Green et al.   Nature Communications

Role and mechanism of action of leucine-rich repeat kinase 1 in bone

(2017) Weirong R Xing et al.   Bone Research

Genome-wide association study of facial morphology reveals novel associations with FREM1 and PARK2

(2017) Myoung Keun Lee et al.   PLoS One

Heritability maps of human face morphology through large-scale automated three-dimensional phenotyping

(2017) Dimosthenis Tsagkrasoulis et al.   Scientific Reports

Human Facial Shape and Size Heritability and Genetic Correlations

(2016) Joanne B. Cole et al.   GENETICS

A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation

(2016) Kaustubh Adhikari et al.   Nature Communications

Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection

(2016) Elissa J. Chesler et al.   G3-Genes Genomes Genetics

The Genetic Architecture of Quantitative Traits Cannot Be Inferred from Variance Component Analysis

(2016) Wen Huang et al.   PLoS Genetics

Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology

(2016) John R. Shaffer et al.   PLoS Genetics

Genomewide Association Study of African Children Identifies Association of SCHIP1 and PDE8A with Facial Size and Shape

(2016) Joanne B. Cole et al.   PLoS Genetics

Human Facial Shape and Size Heritability and Genetic Correlations

(2016) Joanne B. Cole et al.   GENETICS

A mixed model for the relationship between climate and human cranial form

(2015) David C. Katz et al.   AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY

Foxp1/2/4 regulate endochondral ossification as a suppresser complex

(2015) Haixia Zhao et al.   DEVELOPMENTAL BIOLOGY

Runx2: Structure, function, and phosphorylation in osteoblast differentiation

(2015) S. Vimalraj et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The Mouse Universal Genotyping Array: From Substrains to Subspecies

(2015) Andrew P. Morgan et al.   G3-Genes Genomes Genetics

A Multi-Megabase Copy Number Gain Causes Maternal Transmission Ratio Distortion on Mouse Chromosome 2

(2015) John P. Didion et al.   PLoS Genetics

Mapping of Craniofacial Traits in Outbred Mice Identifies Major Developmental Genes Involved in Shape Determination

(2015) Luisa F. Pallares et al.   PLoS Genetics

Use of a natural hybrid zone for genomewide association mapping of craniofacial traits in the house mouse

(2014) Luisa F. Pallares et al.   MOLECULAR ECOLOGY

Advantages and pitfalls in the application of mixed-model association methods

(2014) Jian Yang et al.   NATURE GENETICS

High-Resolution Genetic Mapping in the Diversity Outbred Mouse Population Identifies Apobec1 as a Candidate Gene for Atherosclerosis

(2014) Tangi L. Smallwood et al.   G3-Genes Genomes Genetics

Quantitative Trait Locus Mapping Methods for Diversity Outbred Mice

(2014) D. M. Gatti et al.   G3-Genes Genomes Genetics

Let's Face It—Complex Traits Are Just Not That Simple

(2014) Benedikt Hallgrimsson et al.   PLoS Genetics

FOXP1mutations cause intellectual disability and a recognizable phenotype

(2013) Anna K. Le Fevre et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Epigenetic influence of KAT6B and HDAC4 in the development of skeletal malocclusion

(2013) Ahrin Huh et al.   AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS

High-precision genetic mapping of behavioral traits in the diversity outbred mouse population

(2013) R. W. Logan et al.   GENES BRAIN AND BEHAVIOR

Dissecting High-Dimensional Phenotypes with Bayesian Sparse Factor Analysis of Genetic Covariance Matrices

(2013) D. E. Runcie et al.   GENETICS

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats

(2013) Amelie Baud et al.   NATURE GENETICS

Practical Considerations Regarding the Use of Genotype and Pedigree Data to Model Relatedness in the Context of Genome-Wide Association Studies

(2013) Riyan Cheng et al.   G3-Genes Genomes Genetics

Genome-wide Association Study of Three-Dimensional Facial Morphology Identifies a Variant in PAX3 Associated with Nasion Position

(2012) Lavinia Paternoster et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning

(2012) Deanna G. Wilson et al.   DEVELOPMENTAL BIOLOGY

Cleft palate defect ofDlx1/2−/− mutant mice is caused by lack of vertical outgrowth in the posterior palate

(2012) Juhee Jeong et al.   DEVELOPMENTAL DYNAMICS

High-Resolution Genetic Mapping Using the Mouse Diversity Outbred Population

(2012) Karen L. Svenson et al.   GENETICS

The Genome Architecture of the Collaborative Cross Mouse Genetic Reference Population

(2012)   GENETICS

The diversity outbred mouse population

(2012) Gary A. Churchill et al.   MAMMALIAN GENOME

Improved linear mixed models for genome-wide association studies

(2012) Jennifer Listgarten et al.   NATURE METHODS

Genome-wide association studies in mice

(2012) Jonathan Flint et al.   NATURE REVIEWS GENETICS

A general and simple method for obtainingR2from generalized linear mixed-effects models

(2012) Shinichi Nakagawa et al.   Methods in Ecology and Evolution

A Genome-Wide Association Study Identifies Five Loci Influencing Facial Morphology in Europeans

(2012) Fan Liu et al.   PLoS Genetics

Whole-Exome-Sequencing Identifies Mutations in Histone Acetyltransferase Gene KAT6B in Individuals with the Say-Barber-Biesecker Variant of Ohdo Syndrome

(2011) Jill Clayton-Smith et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

MODULARITY, NOISE, AND NATURAL SELECTION

(2011) Gabriel Marroig et al.   EVOLUTION

Subspecific origin and haplotype diversity in the laboratory mouse

(2011) Hyuna Yang et al.   NATURE GENETICS

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

(2011) Graciana Diez-Roux et al.   PLOS BIOLOGY

Loss of CHSY1, a Secreted FRINGE Enzyme, Causes Syndromic Brachydactyly in Humans via Increased NOTCH Signaling

(2010) Jing Tian et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape

(2010) N. M. Young et al.   DEVELOPMENT

Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth

(2010) Toshiyuki Yoshida et al.   DEVELOPMENTAL DYNAMICS

Entrez Gene: gene-centered information at NCBI

(2010) D. Maglott et al.   NUCLEIC ACIDS RESEARCH

Evidence for the prepattern/cooption model of vertebrate jaw evolution

(2010) R. Cerny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-Related Changes in Craniofacial Morphology in GDF-8 (Myostatin)-Deficient Mice

(2009) Lisa Vecchione et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

New directions in craniofacial morphogenesis

(2009) Heather L. Szabo-Rogers et al.   DEVELOPMENTAL BIOLOGY

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

(2009) Shigetoshi Yokoyama et al.   DEVELOPMENTAL CELL

Deciphering the Palimpsest: Studying the Relationship Between Morphological Integration and Phenotypic Covariation

(2009) Benedikt Hallgrímsson et al.   Evolutionary Biology

Advances in Geometric Morphometrics

(2009) Philipp Mitteroecker et al.   Evolutionary Biology

The genetics of quantitative traits: challenges and prospects

(2009) Trudy F. C. Mackay et al.   NATURE REVIEWS GENETICS

Down-regulation of the forkhead transcription factor Foxp1 is required for monocyte differentiation and macrophage function

(2008) C. Shi et al.   BLOOD

A SHH-responsive signaling center in the forebrain regulates craniofacial morphogenesis via the facial ectoderm

(2008) D. Hu et al.   DEVELOPMENT

Pleiotropic Patterns of Quantitative Trait Loci for 70 Murine Skeletal Traits

(2008) J. P. Kenney-Hunt et al.   GENETICS

A search for quantitative trait loci exhibiting imprinting effects on mouse mandible size and shape

(2008) L J Leamy et al.   HEREDITY

Many sequence variants affecting diversity of adult human height

(2008) Daniel F Gudbjartsson et al.   NATURE GENETICS

Use and misuse of the gene ontology annotations

(2008) Seung Yon Rhee et al.   NATURE REVIEWS GENETICS

Genomic imprinting effects on adult body composition in mice

(2008) J. M. Cheverud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA