Advantages and pitfalls in the application of mixed-model association methods

An Analytical Comparison of the Principal Component Method and the Mixed Effects Model for Association Studies in the Presence of Cryptic Relatedness and Population Stratification

(2013) Kai Wang et al.   HUMAN HEREDITY

FaST-LMM-Select for addressing confounding from spatial structure and rare variants

(2013) Jennifer Listgarten et al.   NATURE GENETICS

Mixed models can correct for population structure for genomic regions under selection

(2013) Jae Hoon Sul et al.   NATURE REVIEWS GENETICS

Response to Sul and Eskin

(2013) Alkes L. Price et al.   NATURE REVIEWS GENETICS

Polygenic Modeling with Bayesian Sparse Linear Mixed Models

(2013) Xiang Zhou et al.   PLoS Genetics

Analysis of case–control association studies with known risk variants

(2012) Noah Zaitlen et al.   BIOINFORMATICS

Link Functions in Multi-Locus Genetic Models: Implications for Testing, Prediction, and Interpretation

(2012) David Clayton   GENETIC EPIDEMIOLOGY

Heritability in the genome-wide association era

(2012) Noah Zaitlen et al.   HUMAN GENETICS

Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis

(2012) S. H. Lee et al.   HUMAN MOLECULAR GENETICS

Improving accuracy of genomic predictions within and between dairy cattle breeds with imputed high-density single nucleotide polymorphism panels

(2012) M. Erbe et al.   JOURNAL OF DAIRY SCIENCE

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Including known covariates can reduce power to detect genetic effects in case-control studies

(2012) Matti Pirinen et al.   NATURE GENETICS

Differential confounding of rare and common variants in spatially structured populations

(2012) Iain Mathieson et al.   NATURE GENETICS

Rapid variance components–based method for whole-genome association analysis

(2012) Gulnara R Svishcheva et al.   NATURE GENETICS

An efficient multi-locus mixed-model approach for genome-wide association studies in structured populations

(2012) Vincent Segura et al.   NATURE GENETICS

A mixed-model approach for genome-wide association studies of correlated traits in structured populations

(2012) Arthur Korte et al.   NATURE GENETICS

Genome-wide efficient mixed-model analysis for association studies

(2012) Xiang Zhou et al.   NATURE GENETICS

Improved linear mixed models for genome-wide association studies

(2012) Jennifer Listgarten et al.   NATURE METHODS

Informed Conditioning on Clinical Covariates Increases Power in Case-Control Association Studies

(2012) Noah Zaitlen et al.   PLoS Genetics

The Covariate's Dilemma

(2012) Joel Mefford et al.   PLoS Genetics

Estimating Missing Heritability for Disease from Genome-wide Association Studies

(2011) Sang Hong Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic inflation factors under polygenic inheritance

(2011) Jian Yang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Genome partitioning of genetic variation for complex traits using common SNPs

(2011) Jian Yang et al.   NATURE GENETICS

FaST linear mixed models for genome-wide association studies

(2011) Christoph Lippert et al.   NATURE METHODS

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Mixed linear model approach adapted for genome-wide association studies

(2010) Zhiwu Zhang et al.   NATURE GENETICS

Variance component model to account for sample structure in genome-wide association studies

(2010) Hyun Min Kang et al.   NATURE GENETICS

Predicting genetic predisposition in humans: the promise of whole-genome markers

(2010) Gustavo de los Campos et al.   NATURE REVIEWS GENETICS

New approaches to population stratification in genome-wide association studies

(2010) Alkes L. Price et al.   NATURE REVIEWS GENETICS

Efficient Control of Population Structure in Model Organism Association Mapping

(2008) H. M. Kang et al.   GENETICS