Mapping of Craniofacial Traits in Outbred Mice Identifies Major Developmental Genes Involved in Shape Determination

Permutation Testing in the Presence of Polygenic Variation

(2015) Mark Abney   GENETIC EPIDEMIOLOGY

Evolution of Darwin’s finches and their beaks revealed by genome sequencing

(2015) Sangeet Lamichhaney et al.   NATURE

DLX3 regulates bone mass by targeting genes supporting osteoblast differentiation and mineral homeostasis in vivo

(2014) J Isaac et al.   CELL DEATH AND DIFFERENTIATION

Heterozygous mutations in cyclic AMP phosphodiesterase-4D (PDE4D) and protein kinase A (PKA) provide new insights into the molecular pathology of acrodysostosis

(2014) Tadashi Kaname et al.   CELLULAR SIGNALLING

Emerging Multifunctional Roles of Claudin Tight Junction Proteins in Bone

(2014) Fatima. Z. Alshbool et al.   ENDOCRINOLOGY

Semi-automatic landmark point annotation for geometric morphometrics

(2014) Paul A Bromiley et al.   Frontiers in Zoology

High-Resolution Genetic Mapping of Complex Traits from a Combined Analysis of F 2 and Advanced Intercross Mice

(2014) Clarissa C. Parker et al.   GENETICS

A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice

(2014) Fubiao Shi et al.   HUMAN MOLECULAR GENETICS

Etiology of craniofacial malformations in mouse models of blepharophimosis, ptosis and epicanthus inversus syndrome

(2014) E. Heude et al.   HUMAN MOLECULAR GENETICS

First Mouse Model for Combined Osteogenesis Imperfecta and Ehlers-Danlos Syndrome

(2014) Frieda Chen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Use of a natural hybrid zone for genomewide association mapping of craniofacial traits in the house mouse

(2014) Luisa F. Pallares et al.   MOLECULAR ECOLOGY

Advantages and pitfalls in the application of mixed-model association methods

(2014) Jian Yang et al.   NATURE GENETICS

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Role of C-type natriuretic peptide signalling in maintaining cartilage and bone function

(2014) N.J. Peake et al.   OSTEOARTHRITIS AND CARTILAGE

Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells

(2014) Irène Aksoy et al.   Nature Communications

Let's Face It—Complex Traits Are Just Not That Simple

(2014) Benedikt Hallgrimsson et al.   PLoS Genetics

Modeling 3D Facial Shape from DNA

(2014) Peter Claes et al.   PLoS Genetics

Inpp4b is a novel negative modulator of osteoclast differentiation and a prognostic locus for human osteoporosis

(2013) Jean Vacher   Annals of the New York Academy of Sciences

Foxc1 controls the growth of the murine frontal bone rudiment by direct regulation of a Bmp response threshold of Msx2

(2013) J. Sun et al.   DEVELOPMENT

Exploring the effects of gene dosage on mandible shape in mice as a model for studying the genetic basis of natural variation

(2013) Louis Boell et al.   DEVELOPMENT GENES AND EVOLUTION

Mutations in SH3PXD2B cause Borrone dermato-cardio-skeletal syndrome

(2013) Gabrielle R Wilson et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Lines of least resistance and genetic architecture of house mouse (Mus musculus) mandible shape

(2013) Louis Boell   EVOLUTION & DEVELOPMENT

A Perspective on Micro-Evo-Devo: Progress and Potential

(2013) Maria D. S. Nunes et al.   GENETICS

The Genetics of Canine Skull Shape Variation

(2013) J. J. Schoenebeck et al.   GENETICS

KLF5 Activates MicroRNA 200 Transcription To Maintain Epithelial Characteristics and Prevent Induced Epithelial-Mesenchymal Transition in Epithelial Cells

(2013) B. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Pitfalls of predicting complex traits from SNPs

(2013) Naomi R. Wray et al.   NATURE REVIEWS GENETICS

Fine Tuning of Craniofacial Morphology by Distant-Acting Enhancers

(2013) C. Attanasio et al.   SCIENCE

Practical Considerations Regarding the Use of Genotype and Pedigree Data to Model Relatedness in the Context of Genome-Wide Association Studies

(2013) Riyan Cheng et al.   G3-Genes Genomes Genetics

Interaction between Foxc1 and Fgf8 during Mammalian Jaw Patterning and in the Pathogenesis of Syngnathia

(2013) Kimberly E. Inman et al.   PLoS Genetics

Genome-wide Association Study of Three-Dimensional Facial Morphology Identifies a Variant in PAX3 Associated with Nasion Position

(2012) Lavinia Paternoster et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Microdeletion del(22)(q12.2) encompassing the facial development-associated gene, MN1 (meningioma 1) in a child with Pierre-Robin sequence (including cleft palate) and neurofibromatosis 2 (NF2): a case report and review of the literature

(2012) Tom B Davidson et al.   BMC Medical Genetics

TINA manual landmarking tool: software for the precise digitization of 3D landmarks

(2012) Anja C Schunke et al.   Frontiers in Zoology

Frank-ter Haar Syndrome Protein Tks4 Regulates Epidermal Growth Factor-dependent Cell Migration

(2012) Gábor Bögel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation

(2012) Gabriel R Linares et al.   JOURNAL OF BONE AND MINERAL RESEARCH

In vivoimpact of Dlx3 conditional inactivation in neural crest-derived craniofacial bones

(2012) Olivier Duverger et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Genome-wide efficient mixed-model analysis for association studies

(2012) Xiang Zhou et al.   NATURE GENETICS

Improved linear mixed models for genome-wide association studies

(2012) Jennifer Listgarten et al.   NATURE METHODS

Initiation of Early Osteoblast Differentiation Events through the Direct Transcriptional Regulation of Msx2 by FOXC1

(2012) Farideh Mirzayans et al.   PLoS One

Variation of BMP3 Contributes to Dog Breed Skull Diversity

(2012) Jeffrey J. Schoenebeck et al.   PLoS Genetics

A Genome-Wide Association Study Identifies Five Loci Influencing Facial Morphology in Europeans

(2012) Fan Liu et al.   PLoS Genetics

A comparative assessment of mandible shape in a consomic strain panel of the house mouse (Mus musculus) - implications for epistasis and evolvability of quantitative traits

(2011) Louis Boell et al.   BMC EVOLUTIONARY BIOLOGY

Inositol Polyphosphate 4-Phosphatase B as a Regulator of Bone Mass in Mice and Humans

(2011) Mathieu Ferron et al.   Cell Metabolism

Genetic determination of human facial morphology: links between cleft-lips and normal variation

(2011) Stefan Boehringer et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

THE QTN PROGRAM AND THE ALLELES THAT MATTER FOR EVOLUTION: ALL THAT'S GOLD DOES NOT GLITTER

(2011) Matthew V. Rockman   EVOLUTION

Mouse genomic variation and its effect on phenotypes and gene regulation

(2011) Thomas M. Keane et al.   NATURE

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

The evolutionary origin of orphan genes

(2011) Diethard Tautz et al.   NATURE REVIEWS GENETICS

The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse

(2011) J. T. Eppig et al.   NUCLEIC ACIDS RESEARCH

A Robust, Simple Genotyping-by-Sequencing (GBS) Approach for High Diversity Species

(2011) Robert J. Elshire et al.   PLoS One

Sh3pxd2b Mice Are a Model for Craniofacial Dysmorphology and Otitis Media

(2011) Bin Yang et al.   PLoS One

Dark Matter: Are Mice the Solution to Missing Heritability?

(2011) Clarissa C. Parker et al.   Frontiers in Genetics

Disruption of the Podosome Adaptor Protein TKS4 (SH3PXD2B) Causes the Skeletal Dysplasia, Eye, and Cardiac Abnormalities of Frank-Ter Haar Syndrome

(2010) Zafar Iqbal et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Manifold functions of the Nail-Patella Syndrome gene Lmx1b in vertebrate development

(2010) Jin-Xia Dai et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Cranial base abnormalities in osteogenesis imperfecta: Phenotypic and genotypic determinants

(2010) Moira S Cheung et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoblastic molecular scaffold Gab1 is required for maintaining bone homeostasis

(2010) T. Weng et al.   JOURNAL OF CELL SCIENCE

MorphoJ: an integrated software package for geometric morphometrics

(2010) CHRISTIAN PETER KLINGENBERG   Molecular Ecology Resources

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

A Simple Genetic Architecture Underlies Morphological Variation in Dogs

(2010) Adam R. Boyko et al.   PLOS BIOLOGY

Commercially Available Outbred Mice for Genome-Wide Association Studies

(2010) Binnaz Yalcin et al.   PLoS Genetics

Spatial and temporal expression of KLF4 and KLF5 during murine tooth development

(2009) Zhuo Chen et al.   ARCHIVES OF ORAL BIOLOGY

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

GENETIC ANALYSIS OF SKULL SHAPE VARIATION AND MORPHOLOGICAL INTEGRATION IN THE MOUSE USING INTERSPECIFIC RECOMBINANT CONGENIC STRAINS BETWEEN C57BL/6 AND MICE OF THEMUS SPRETUSSPECIES

(2009) Gaëtan Burgio et al.   EVOLUTION

Osteogenesis imperfecta: Recent findings shed new light on this once well-understood condition

(2009) Donald Basel et al.   GENETICS IN MEDICINE

Meningioma 1 Is Required for Appropriate Osteoblast Proliferation, Motility, Differentiation, and Function

(2009) Xiaoxue Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The podosomal-adaptor protein SH3PXD2B is essential for normal postnatal development

(2009) Mao Mao et al.   MAMMALIAN GENOME

The Novel Adaptor Protein Tks4 (SH3PXD2B) Is Required for Functional Podosome Formation

(2009) Matthew D. Buschman et al.   MOLECULAR BIOLOGY OF THE CELL

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

TBX15 Mutations Cause Craniofacial Dysmorphism, Hypoplasia of Scapula and Pelvis, and Short Stature in Cousin Syndrome

(2008) Ekkehart Lausch et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A search for quantitative trait loci exhibiting imprinting effects on mouse mandible size and shape

(2008) L J Leamy et al.   HEREDITY

Osteoblasts express claudins and tight junction-associated proteins

(2008) Kannikar Wongdee et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Expression profiles of phosphodiesterase 4D splicing variants in osteoblastic cells

(2008) Chizumi Nomura-Furuwatari et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Progress and challenges in genome-wide association studies in humans

(2008) Peter Donnelly   NATURE

Sizing up human height variation

(2008) Peter M Visscher   NATURE GENETICS